Wen-Liang Yu

ORCID: 0000-0002-3932-7516
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About
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Research Areas
  • Sepsis Diagnosis and Treatment
  • Respiratory Support and Mechanisms
  • Surface Treatment and Residual Stress
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Radiotherapy Techniques
  • Metal and Thin Film Mechanics
  • Intensive Care Unit Cognitive Disorders
  • Hemodynamic Monitoring and Therapy
  • Medical Imaging Techniques and Applications
  • Chronic Lymphocytic Leukemia Research
  • Cardiac Arrest and Resuscitation
  • Neonatal Respiratory Health Research
  • Titanium Alloys Microstructure and Properties
  • Renal function and acid-base balance
  • Advanced X-ray and CT Imaging
  • Cytomegalovirus and herpesvirus research
  • COVID-19 Clinical Research Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antifungal resistance and susceptibility
  • Poisoning and overdose treatments
  • High Entropy Alloys Studies
  • Infections and bacterial resistance
  • Acute Kidney Injury Research
  • Electrodeposition and Electroless Coatings
  • Microscopic Colitis

Shanghai Jiao Tong University
2023-2024

Wenzhou Medical University
2024

China Pharmaceutical University
2021-2023

Quzhou City People's Hospital
2014-2023

Nanjing University
2019-2022

Macau University of Science and Technology
2017-2019

Changzhou University
2019

Nanjing Children's Hospital
2008-2017

Chi Mei Medical Center
2015-2017

Taipei Medical University
2017

To predict the voxel-based dose distribution for postoperative cervical cancer patients underwent volumetric modulated arc therapy using deep learning models.A total of 254 with received in authors' hospital from January 2018 to September 2021 were enrolled this retrospective study. Two networks (3D residual neural network and 3DUnet) adapted train (203 cases) test (51 feasibility effectiveness prediction method. The performance models was evaluated by comparing results those treatment...

10.1177/15330338231167039 article EN cc-by-nc Technology in Cancer Research & Treatment 2023-01-01

KRAS mutations are frequently detected in non-small cell lung cancers (NSCLCs). Although covalent KRASG12C inhibitors have been developed to treat KRASG12C-mutant cancers, effective treatments still lacking for other KRAS-mutant NSCLCs. Thus, identifying a effector that confers poor prognosis would provide an alternative strategy the treatment of KRAS-driven cancers. Here, we show drives expression deubiquitinase USP13 through Ras-responsive element-binding protein 1 (RREB1). Elevated...

10.1016/j.celrep.2023.113511 article EN cc-by-nc-nd Cell Reports 2023-12-01

To integrate radiomics and dosiomics features from multiple regions in the radiation pneumonia (RP grade ≥ 2) prediction for esophageal cancer (EC) patients underwent radiotherapy (RT).

10.1186/s13014-024-02462-1 article EN cc-by Radiation Oncology 2024-06-08

The impact of granulocyte-macrophage colony stimulating factor (GM-CSF) on hematologic indexes and complications remains existing contradictory evidence in cancer patients after treatment chemotherapy. Eligible studies up to March 2017 were searched reviewed from PubMed Wanfang databases. Totally 1043 15 included our research. result indicated that GM-CSF could significantly improve white blood cells count (SMD = 1.16, 95% CI: 0.71 - 1.61, Z 5.03, P < 0.00001) reduce the time leukopenia...

10.18632/oncotarget.24890 article EN Oncotarget 2018-06-15

To investigate the feasibility of constant dose rate volumetric modulated arc therapy (CDR-VMAT) in treatment nasopharyngeal cancer (NPC) patients and to introduce rotational radiotherapy for linacs incapable variation.Twelve NPC with various stages treated previously using variable (VDR) VMAT were enrolled this study. CDR-VMAT, VDR-VMAT mutlicriteria optimization (MCO) plans generated each patient on RayStation planning system identical objective functions dosimetric differences among these...

10.1186/s13014-014-0235-1 article EN cc-by Radiation Oncology 2014-11-03

The Fas-associated death domain (FADD) has long been regarded as a crucial adaptor protein in the extrinsic apoptotic pathway.Despite non-apoptotic function of FADD is gradually being discovered and confirmed, its corresponding physiological pathological significance still unclear.Based on database GWAS catalog GTEx Portal, 17 SNPs associated with leukemia susceptibility were found to be linked expression.We then investigated regulatory role T-acute lymphoblastic (T-ALL) using Jurkat cells...

10.7150/ijbs.68016 article EN cc-by-nc International Journal of Biological Sciences 2022-01-01

The aim of this study was to investigate the feasibility and sensitivity using individual volume–based 3D gamma indices for composite dose–volume histogram (DVH)–based intensity-modulated radiation therapy (IMRT) quality assurance (QA). Composite IMRT QA 15 cervical cancer patients performed with ArcCHECK. percentage dosimetric errors (%DEs) DVH metrics when comparing treatment planning system QA-reconstructed dose distribution, passing rates (%GPs) different criteria volumes global were...

10.1093/jrr/rry061 article EN cc-by-nc Journal of Radiation Research 2018-07-14

To investigate the thermal stability of a shot-peened specimen and ensure reliability operation under high temperatures, CNT/Al-Cu-Mg composites were treated by shot peening (SP) isothermal aging treatment. The heating temperatures 100, 150, 200, 250 °C. Changes in surface residual stress distribution along depth investigated. microstructure changes analyzed XRD observed TEM. mechanical properties characterized microhardness. results show that compressive (CRS) release mainly occurred at...

10.3390/coatings14121571 article EN Coatings 2024-12-16

Sepsis and septic shock is one of the major death causes in Chinese pediatric critical care. This review has brought to this issue with very recent advances clinical investigation aspect published literature. In report, management sepsis, severe sepsis as well other complications were carried out both multicenter or single center studies, mostly according international definitions recommendations for shock. The resources these reports, though not complete, represent different regions leading...

10.3233/jpi-2009-0156 article EN Journal of Pediatric Infectious Diseases 2015-07-28

Acute pulmonary embolism (PE) often occurs in some patients with hereditary and acquired factors predisposing them at a risk for the development of thrombotic events.The hypercoagulable state due to genetic mutations involves loss endothelium non-thrombogenic protective factors, thus linking an increase blood clots.The are commonly seen infectious diseases, such as influenza, whereas dengue fever has been rarely described.Influenza diseases international public health importance their...

10.15761/gimci.1000148 article EN General Internal Medicine and Clinical Innovations 2017-01-01

10.1016/j.jmii.2015.02.651 article EN Journal of Microbiology Immunology and Infection 2015-03-28

10.1016/j.jmii.2015.02.477 article EN Journal of Microbiology Immunology and Infection 2015-03-28

Background and aims: Previous study have proved the important of angiopoietins in adult ARDS. Aims: To explore relationship between Angiopioetin-1(Ang1)?Ang2?Ang1/Ang2 levels severity ARDS pediatric intensive care unit (PICU). Methods: 64 cases a PICU general surgery department admitted from April 1, 2012 to March 31, 2013 were enrolled this study. 22 allocated into group; 23 non-ARDS that received mechanical ventilation group I; 20 non-pulmonary disease pre-surgery II. The serum level Ang1,...

10.1097/01.pcc.0000449224.82454.f8 article EN Pediatric Critical Care Medicine 2014-05-01

The definition of severe sepsis has been renewed in 2012 international guidelines for management and septic shock.This article summarizes briefly respiratory support strategy which incorporated with new guideline recent progress mechanical ventilation (MV). Oxygen therapy, indication ventilation, the roles MV on shock, drug selection, hemodynamic monitoring are included this article. Key words: Sepsis; Respiratory support; Mechanical ventilation; Child

10.3760/cma.j.issn.2095-428x.2015.06.003 article EN Zhonghua shiyong erke linchuang zazhi 2015-03-20
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