A5103245044- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Mycotoxins in Agriculture and Food
- Structural Behavior of Reinforced Concrete
- Biofuel production and bioconversion
- Advanced materials and composites
- Innovative concrete reinforcement materials
- RNA Research and Splicing
- Diet, Metabolism, and Disease
- Sesquiterpenes and Asteraceae Studies
- High-Temperature Coating Behaviors
- Enzyme-mediated dye degradation
- Microbial Metabolites in Food Biotechnology
- Advanced Photocatalysis Techniques
- Agricultural Engineering and Mechanization
- Cardiac Structural Anomalies and Repair
- Renal function and acid-base balance
- Gynecological conditions and treatments
- Cerebral Palsy and Movement Disorders
- Plant Pathogens and Resistance
- Advanced Nanomaterials in Catalysis
- Microstructure and mechanical properties
- Natural Fiber Reinforced Composites
- Metabolism and Genetic Disorders
- Structural Response to Dynamic Loads
First Affiliated Hospital of Bengbu Medical College
2022-2024
Zhengzhou Central Hospital
2022-2024
Henan University of Technology
2024
Guangzhou University of Chinese Medicine
2023-2024
Jiangnan University
2021-2023
State Key Laboratory of Food Science and Technology
2021-2023
Ministry of Transport
2022-2023
Bengbu Medical College
2022-2023
Wenzhou Central Hospital
2023
Bengbu University
2022
Although the strain-dependent effects of Bacteroides vulgatus on alleviating intestinal inflammatory diseases have been demonstrated, literature has rarely focused underlying causes this effect. In study, we selected four B. strains (FTJS5K1, FTJS7K1, FSDTA11B14, and FSDLZ51K1) with different genomic characteristics evaluated their protective roles against dextran sulfate sodium- (DSS-) induced colitis. Compared to other three tested strains, 7K1 more strongly ameliorated DSS-induced weight...
Aflatoxins are naturally occurring high-toxic secondary metabolites, which cause worldwide environmental contaminations and wastes of food feed resources severely threaten human health. Thus, the highly efficient methods technologies for detoxification aflatoxins urgently needed in a long term. In this work, we report construction recombinant Kluyveromyces lactis strains GG799(pKLAC1-Phs mnp ), GG799(pKLAC1-Plo GG799(pKLAC1-Phc then food-grade expression three manganese peroxidases these...
Abstract Aflatoxin B 1 (AFB ) and zearalenone (ZEN) are two predominant mycotoxins ubiquitously found in corn, peanuts, other grains, which pose a great threat to human health. Therefore, safe effective methods for detoxification of these urgently needed. To achieve simultaneous degradation multiple mycotoxins, fusion enzyme ZPF1 was constructed by linking hydrolase manganese peroxidase with linker peptide GGGGS. This secretory expressed successfully the newly food-grade recombinant strain...
As a novel therapeutic approach, photothermal therapy (PTT) combined with chemotherapy can synergistically produce antitumor effects. Herein, dithiodipropionic acid (DTDP) was used as donor of disulfide bonds sensitive to the tumor microenvironment for establishing chemical bonding between photosensitizer indocyanine green amino (ICG-NH
Abstract Objective Cancer is a predominant cause of death globally. PHD-finger domain protein 5 A (PHF5A) has been reported to participate in various cancers; however, there no pan-cancer analysis PHF5A. This study aims present novel prognostic biomarker and therapeutic target for cancer treatment. Methods explored PHF5A expression its impact on prognosis, tumor mutation burden (TMB), microsatellite instability (MSI), functional status immunity across cancers using public databases,...
Aflatoxin B
Background: Braking force is a gait marker associated with stability. This study aimed to determine the alteration of braking and its correlation stability in Alzheimer disease (AD). Methods: A total 32 AD patients healthy controls (HCs) were enrolled this study. Gait parameters (braking force, variability, fall risk) walking tests Free walk, Barrier, Count backward measured by JiBuEn® analysis system. variability was calculated coefficient variation (COV) stride time, stance swing time....
l-Phenyllactic acid (l-PLA) is a small molecular organic that exhibits powerful capacity for inhibition against foodborne pathogens. In this work, we developed new cost-effective and environmentally friendly process the biosynthesis of l-PLA. This strategy designed novel whole-cell biotransformation system employing two heterologous enzymes, namely, phenylalanine dehydrogenase (PheDH) l-hydroxyisocaproate (l-HicDH). The novelty lies in first-time utilization these which not only enables...
Ventricular septal rupture (VSR) is a mechanical complication of acute myocardial infarction (AMI), and its mortality has not decreased significantly in recent decades. However, no clinical model been developed to predict short-term patients with post-infarction VSR (PIVSR). This study aimed develop nomogram the 30-day by using characteristics hospitalized PIVSR. The least absolute shrinkage selection operator (LASSO) multivariate logistic regression analysis was used construct R. evaluated...
Background: Abnormal accumulation of copper could induce cell death and tumor growth, affect immune escape by regulating programmed ligand 1 (PD-L1) expression. This study aims to establish verify a risk signature based on cuproptosis- immune-related genes (CIRGs) for hepatocellular carcinoma (HCC) management.
Abstract Background: Shock index-based risk indices predicting in-hospital mortality for ST-elevation myocardial infarction (STEMI) patients have been recently described, debate continues about their accuracy, especially compared with classic scoring system. Thus, we aim to evaluate the predictive value of shock in STEMI and thrombolysis (TIMI) score. Method: Consecutive 5063 were divided into 2 groups: non-survivor (392, 7.7%) survivor (4671, 92.3%). Predictive performance TIMI score...
To study the mechanical damage of sesame seeds in planting, harvesting and threshing, static compression test finite element simulation were carried out on Zhengzhi HL05 seeds. Based experimental results, given same moisture content, have largest crushing load under flat compression, second lateral smallest vertical compression; when loading direction is same, elastic modulus, maximum deformation decrease with increase content; modulus within range 1.64MPa-7.06MPa, ranges from 0.23mm to...
Background Abnormal accumulation of copper could induce cell death and tumor growth, affect immune escape by regulating PD-L1 expression. Cuproptosis- immune-related genes (CIRGs) are yet to be fully understood in hepatocellular carcinoma (HCC).Methods HCC RNA-seq clinical data were obtained from open databases. Lasso Cox regression analyses utilized screen CIRGs develop a risk signature. The signature's value for applications, functional enrichment, mutation burden (TMB), profile...
Mikania micrantha is a perennial liana of the genus Asteraceae family. It commonly used medicine in South America for treating fever, malaria, dysentery, snake bites, etc. Because its strong adaptability and ability to inhibit growth associated plants, considered an invasive species China known as plant killer. Preliminary studies have shown that has antipruritic effect, but active substance not yet clear. In this study, 4-aminopyridine-induced itching model mice was determine effects...
Congenital chloride diarrhea (CCD) is a rare but significant genetic disorder characterized by severe electrolyte imbalances resulting from impaired intestinal absorption.Affected children experience persistent diarrhea, dehydration, and malnutrition, complicating medical developmental care.The enhancement of prenatal detection crucial for improved patient management, early interventions, informed counseling.However, despite advancements in medicine, the complex nature rarity CCD make...