A5000317643- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Biomedical Text Mining and Ontologies
- Radiology practices and education
- Advanced MRI Techniques and Applications
- Medical Image Segmentation Techniques
- Sodium Intake and Health
- Breast Lesions and Carcinomas
- Digital Radiography and Breast Imaging
- Management of metastatic bone disease
- Cardiac Imaging and Diagnostics
- AI in cancer detection
- Congenital Heart Disease Studies
- Angiogenesis and VEGF in Cancer
- Bone health and treatments
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Semantic Web and Ontologies
- Lung Cancer Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Prostate Cancer Treatment and Research
- Thermoregulation and physiological responses
Universitätsklinikum Erlangen
2013-2022
Friedrich-Alexander-Universität Erlangen-Nürnberg
2012-2022
Research Institute of Radiology
2021
Steinbeis University Berlin
2017
Siemens (Germany)
2017
Siemens Healthcare (Germany)
2016
Vanderbilt University
2013
Zero to Three
2010
High dietary salt intake is associated with hypertension; the prevalence of salt-sensitive hypertension increases age. We hypothesized that tissue Na + might accumulate in hypertensive patients and aging be accompanied by deposition tissue. implemented 23 magnetic resonance imaging to measure content soft tissues vivo earlier, but had not studied essential hypertension. report on a cohort 56 healthy control men women, 57 women The ages ranged from 22 90 years. measurements were made at level...
Objective Na+ can be stored in muscle and skin without commensurate water accumulation. The aim of this study was to assess H2O with MRI acute heart failure patients before after diuretic treatment a healthy cohort. Methods Nine (mean age 78 years; range 58–87) nine gender-matched controls were studied. They underwent 23Na/1H-MRI at the calf custom-made knee coil. Patients studied therapy. 23Na-MRI gray-scale measurements Na+-phantoms served quantify Na+-concentrations. A fat-suppressed...
To evaluate a computer-aided detection (CADe) system for lytic and blastic spinal metastases on computed tomography (CT). We retrospectively evaluated the CADe 20 consecutive patients with 42 30 172 metastases. The was trained using CT images of 114 subjects 102 308 Lesions were annotated by experienced radiologists. Detected benign lesions considered false-positive findings. Detector sensitivity number findings calculated as criteria detector performance, free-response receiver operating...
Objective. Skin fibrosis is the predominant feature of SSc and arises from excessive extracellular matrix deposition. Glycosaminoglycans are macromolecules matrix, which facilitate Na+ accumulation in skin. We used 23Na-MRI to quantify hypothesized that skin might accumulate be a biomarker for fibrosis. Methods. In this observational case–control study, was determined by using volume coil 12 patients with diffuse cutaneous 21 control subjects. assessed modified Rodnan score prior on...
Dual-energy computed tomographic angiography (DE-CTA) has been demonstrated to improve the visualization of head and neck vessels. The aim this study was test potential split-filter single-source dual-energy CT automatically remove bone from final CTA data set.Dual-energy performed in 50 consecutive patients evaluate supra-aortic arteries, either grade carotid artery stenosis or rule out traumatic dissections. on a 128-slice system equipped with special filter array separate 120-kV spectrum...
Vascularization of bioartificial matrices is crucial for successful tissue engineering. Endothelial progenitor cells (EPC) have shown vascularization potential in ischemic conditions and may also support blood vessel formation tissue-engineered matrices. The aim our study was to investigate the impact a well-characterized murine embryonal EPC line (T17b-EPC) on fibrovascular granulation after suspension fibrine matrix followed by subcutaneous implantation separation chamber rats. were...
Background: The goal of this study was to assess the prevalence disordered eating and exercise dependence among elite amateur endurance athletes, both male female, find out whether there an association between addiction in these athletes. Methods: 1031 participants major German events (745 male, 286 528 athletes 503 hobby athletes) with a mean age 41.6 ± 10.7 years old completed set questionnaires, including SCOFF questionnaire Exercise Addiction Inventory (EAI). Results: A rate 18.9%...
Pancreas segmentation in 3-D computed tomography (CT) data is of high clinical relevance, but extremely difficult since the pancreas often not visibly distinguishable from small bowel. So far no automated approach using only single phase contrast enhancement exist. In this work, a novel fully algorithm to extract such CT images proposed. Discriminative learning used build tissue classifier that incorporates spatial relationships between and surrounding organs vessels. Furthermore, discrete...
Many publications describe the use of diffusion-weighted imaging (DWI) in breast MRI. This article addresses question when to apply DWI sequence course scan protocol. The effect T1-shortening contrast media (CM) on ADC values lesions is investigated.Data were acquired a 1.5 T scanner. 60 patients with 79 (20 benign, 59 malignant) included. (4 mm slice thickness, b-values: 50, 400, 800) was applied before and after CM administration. Before calculating map, b50, b400 b800 series analyzed...
Being able to segment the esophagus without user interaction from 3-D CT data is of high value radiologists during oncological examinations mediastinum. The segmentation can serve as a guideline and prevent confusion with pathological tissue. However, limited contrast surrounding structures versatile shape appearance make challenging problem. This paper presents multistep method. First, detector that trained learn discriminative model combined an explicit distribution respiratory esophageal...
Future radiology practices assume that the reports should be uniform, comprehensive, and easily managed. This means must readable to humans machines alike. In order improve reporting in breast imaging, we allow radiologist write structured with a special pen on paper an invisible dot pattern. this way, provide knowledge‐acquisition system for printed mammography patient forms combined work digital documents. domain, documents cannot replaced by computer systems because they contain free‐form...