A5008303958- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- HER2/EGFR in Cancer Research
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Eosinophilic Esophagitis
- Radiopharmaceutical Chemistry and Applications
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Melanoma and MAPK Pathways
- Cancer-related Molecular Pathways
- Cancer Mechanisms and Therapy
- Helicobacter pylori-related gastroenterology studies
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Diagnosis and Treatment
- Dysphagia Assessment and Management
- Advanced Breast Cancer Therapies
- Metastasis and carcinoma case studies
- Chronic Lymphocytic Leukemia Research
- Biosimilars and Bioanalytical Methods
- Synthesis and biological activity
- Colorectal and Anal Carcinomas
- Cytokine Signaling Pathways and Interactions
- Protein Degradation and Inhibitors
University of Padua
2019-2025
IRCCS Policlinico San Donato
2024
Erasmus MC
2024
Baylor College of Medicine
2021
Breast Cancer (BC) is the second most common type of cancer worldwide and displays highest cancer-related mortality among women worldwide. Targeted therapies have revolutionized way BC has been treated in last decades improving life expectancies millions women. Among different molecular pathways that interest for development targeted are Cyclin-Dependent Kinases (CDK). CDK inhibitors a class molecules already exist nature those belonging to INK4 protein family specifically inhibit CDK4/6...
There is no consensus on the definition of failure after treatment in patients with achalasia. The Eckardt score used to define clinical outcomes. However, objective metrics are lacking. This study aimed identify whether any high-resolution manometry (HRM) parameters may be useful predicting a positive outcome laparoscopic Heller-Dor (LHD).
Background Esophageal rhabdomyosarcoma is an exceedingly rare malignant tumor, with only three cases comprehensively documented in the literature since 1995. Due to its rarity, there limited information on epidemiology and diagnosis of this disease, no standardized treatment protocols have been established. As a result, both recognition management esophageal pose significant challenges. The present case report provides valuable insight into clinical approach highlighting need for further...
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The medical research field has been tremendously galvanized to improve the prediction of therapy efficacy by revolution in artificial intelligence (AI). An earnest desire find better ways predict effectiveness with use AI propelled evolution new models which it can become more applicable clinical settings such as breast cancer detection. However, some instances, U.S. Food and Drug Administration was obliged back previously approved inaccurate for AI-based prognostic because they eventually...
The medical research field has been tremendously galvanized to improve the prediction of therapy efficacy by revolution in artificial intelligence (AI). An earnest desire find better ways predict effectiveness with use AI propelled evolution new models which it can become more applicable clinical settings such as breast cancer detection. However, some instances, U.S. Food and Drug Administration was obliged back previously approved inaccurate for AI-based prognostic because they eventually...
Abstract Background Pathophysiology of GERD is complex and esophageal motility disorders are frequently contributing to the disease. Most existing literature demonstrates that Laparoscopic Fundoplication (LF) safe in setting ineffective or weak peristalsis, however effect wrap on still debated. This study aimed assess how a functioning effective fundoplication could impact patients with GERD. Methods We analyzed prospectively collected data who underwent laparoscopic Nissen (LN) Toupet (LT)...
Abstract Background Minimally invasive esophagectomy has demonstrated non-inferiority in terms of surgical and oncologic outcomes compared with open esophagectomy, better short-term outcomes. The learning curve this procedure is protracted before a plateau ideal results reached. purpose study to evaluate the safety efficacy implementing totally minimally program for cancer high-volume center impact on perioperative Methods This retrospective non-randomized control study. includes 199...
Abstract Background Esophagogastric junction (EGJ) Siewert type II tumors pose unique challenges in terms of adequate surgical treatment due to their anatomical location and potential for abdominal mediastinal lymph node metastasis. The optimal approach these remains a topic debate, with options including transhiatal extended gastrectomy or transthoracic esophagectomy. Understanding the different outcomes associated interventions is crucial informed decision-making patient-tailored...
Abstract Background There is no consensus on the definition of failure after treatment in patients with esophageal achalasia. The Eckardt score (ES) commonly used to define clinical outcome, but objective metrics based high-resolution manometry (HRM) or other tools are lacking. Aim this study was identify any HRM parameters useful predict a positive outcome surgical laparoscopic Heller-Dor (LHD). Methods Patients who had undergone LHD between 2012 and 2022, pre- postoperative at our Center,...