Randy Ko

ORCID: 0000-0002-3947-1956
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About
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Research Areas
  • Epigenetics and DNA Methylation
  • Psoriasis: Treatment and Pathogenesis
  • Cutaneous Melanoma Detection and Management
  • melanin and skin pigmentation
  • Healthcare Systems and Reforms
  • Cell Adhesion Molecules Research
  • Social Media in Health Education
  • Healthcare Systems and Challenges
  • Academic Publishing and Open Access
  • Herpesvirus Infections and Treatments
  • Dermatologic Treatments and Research
  • Asthma and respiratory diseases
  • Genetic Syndromes and Imprinting
  • Vitamin D Research Studies
  • Orthopedic Surgery and Rehabilitation
  • scientometrics and bibliometrics research
  • Skin Protection and Aging
  • Pharmacological Effects of Natural Compounds
  • Burn Injury Management and Outcomes
  • Nonmelanoma Skin Cancer Studies
  • Immune responses and vaccinations
  • Vascular Tumors and Angiosarcomas
  • Angiogenesis and VEGF in Cancer
  • Ocular Oncology and Treatments
  • Cancer-related molecular mechanisms research

University of New Mexico
2016-2024

Abstract Superficial skin erosion wounds are very common in the clinic, and conventional treatments not always effective; thus, effective novel therapy is needed. Cold atmospheric plasma (CAP) has been recognised as a promising approach to wound healing. The purpose of this study show potential clinical application CAP for healing different kinds superficial wounds. Seven patients with (two pyoderma gangrenosum, two trauma would, one patient giant genital wart, diabetic foot, chronic eczema)...

10.1111/iwj.13161 article EN International Wound Journal 2019-06-17

Abstract Text Estrogens regulate numerous physiological and pathological processes, including wide-ranging effects in wound healing. The of estrogens are mediated through multiple estrogen receptors (ERs), the classical nuclear ERs (ERα ERβ), that typically gene expression, 7-transmembrane G protein-coupled receptor (GPER), predominantly mediates rapid “non-genomic” signaling. Estrogen modulates expression various genes involved epidermal function regeneration, inflammation, matrix...

10.1210/endocr/bqaf043.009 article EN Endocrinology 2025-04-01

Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and altered keratinocyte differentiation inflammation caused the interplay of genetic environmental factors. Previous studies have revealed that DNA methylation (DNAm) makers are closely associated with psoriasis, strong evidences shown DNAm can be controlled factors, which attracted us to evaluate relationship among DNAm, makers, status.We utilized genome-wide data psoriatic (PP, N = 114)...

10.1186/s13148-016-0297-z article EN cc-by Clinical Epigenetics 2016-12-01

Background: Artificial intelligence (AI) has become a powerful tool and is attracting more attention in the field of medicine. There are number AI studies focusing on skin diseases, there many products that have been applied dermatology. However, attitudes dermatologists, specifically those from China, towards AI, not clear as few, if any focused this issue. Methods: A web-based questionnaire was designed by experts Chinese Skin Image Database (CSID) published UMER Doctor platform (an online...

10.21037/atm.2019.12.102 article EN Annals of Translational Medicine 2020-06-01

Objective: Dermoscopic features of cutaneous vascular anomalies have been reported, but the described currently known are limited and not well-understood. The aim this study is to comprehensively summarize compare dermoscopic four different types [infantile hemangiomas (IH), cherry angioma (CA), angiokeratomas (AK), pyogenic granuloma (PG)] in Chinese Han population. Materials Methods: 31 IH, 172 CA, AK, 45 PG were collected based on contact non-polarized mode dermoscopy at 20-fold...

10.3389/fmed.2021.692060 article EN cc-by Frontiers in Medicine 2021-06-28

Psoriasis (Ps) is a common chronic inflammatory skin disease. The keratinocytes of psoriatic defy normal apoptosis and exhibit active cell proliferation. Aberrant DNA methylation (DNAm) has been suggested relevant through regulating the expression Ps susceptibility genes. However, it unclear whether biological age inferred from methylome affected. To address above issue, we applied recently developed clock model to our Chinese Han population dataset, which includes DNAm data 114 involved...

10.1186/s13148-018-0584-y article EN cc-by Clinical Epigenetics 2018-12-01

Subungual splinter hemorrhage (SSH) is a common nail disorder and difficult to differentiate from other diseases because of their similar characteristics. The epidemiological study SSH lacking it unclear whether needs treatment or not.The aims this were observe the clinical characteristics toenails in Chinese adults provide reference for diagnosis prognosis patients with SSH.We collected followed up 63 who diagnosed through dermoscopic examination. characteristics, disease course, recovery...

10.4103/ijd.ijd_193_18 article EN cc-by-nc-sa Indian Journal of Dermatology 2020-01-01

Estrogens regulate numerous physiological and pathological processes, including wide-ranging effects in wound healing. The of estrogens are mediated through multiple estrogen receptors (ERs), the classical nuclear ERs (ERα ER $${\upbeta }$$ ), that typically gene expression, 7-transmembrane G protein-coupled receptor (GPER), predominantly mediates rapid "non-genomic" signaling. Estrogen modulates expression various genes involved epidermal function regeneration, inflammation, matrix...

10.1038/s41598-024-68620-3 article EN cc-by-nc-nd Scientific Reports 2024-08-08

Abstract Background: The prevalence of skin diseases and diabetes mellitus (DM) are prominent around the world. current scope knowledge regarding comorbidities with type 2 DM (T2DM) is limited, leading to limited recognition correlations between T2DM. Methods: We collected 383 subjects from Da Qing Diabetes Study during period July 9th September 1st, 2016. were categorized into three groups: Normal glucose tolerance (NGT), impaired (IGT), clinical characteristics recorded investigated....

10.1097/cm9.0000000000001453 article EN cc-by-nc-nd Chinese Medical Journal 2021-04-14
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