In a series of 701 infants born to diabetic women between 1950 and 1974 ,57(8-1 percent) had congential malformations which is rate three four timeshigher than in the normal populations Birmingham.. 26 cases(3-8 per cent) were fatal accounted for cent perinatal mortality series. Central nervous system, cardiovascular skeletal abnormalities equally common there was high incidence anencephalus, spina bifida, transposition great vessels sacral dysgenesis...

Hypogonadism, usually hypogonadotropic in origin, is the most common nondiabetic endocrinopathy hereditary hemochromatosis (HH). Early studies, evaluating small numbers of patients with advanced HH, report prevalence rates 10-100%. The clinical presentation HH has changed recent years as a result increased awareness and screening. We assessed hypogonadism large group diagnosed single center over past 20 yr, period follow-up spanning time before after widespread screening was introduced HFE...

Fourteen adults in whom diabetes mellitus and coeliac disease coexist, are described. In no patient was diagnosed (biopsy proven) before the age of 28 years. Diabetes recognized all except one. Diabetic control very unstable hypoglycaemia particularly troublesome treatment with a gluten free diet. Following restriction, insulin requirement increased six patients, diabetic became more stable. Diarrhoea due to coexisting diabetes, may be mistakenly as ‘diabetic diarrhoea’. However, certain...

Pituitary function was assessed in twelve male patients with idiopathic hemochromatosis. Though clinical features suggestive of hypogonadism were noted nine cases, impaired pituitary demonstrated only two instances. Our findings suggest that factors other than or testicular failure contribute significantly to the occurrence sexual hypofunction and seen many these patients.

The effect of moderate amounts alcohol on control diabetes has been studied in twenty patients. No deterioration occurred after alcohol. Two subjects became severely hypoglycemic following implications the use by diabetic patients are discussed.

The high prevalence of celiac disease in patients with autoimmune hypothyroidism, compared to the general population, has been well documented but screening for is not recommended as yet otherwise asymptomatic hypothyroid patients. In recent years undiagnosed largely a result many atypical manifestations disease, become apparent. We report case 58-year-old woman hypothyroidism who was initially suspected having on basis apparent resistance levothyroxine therapy, and had no other clinical or...

In a one-year follow-up study the insulin dose in diabetic patients using very pure porcine was compared with that conventional preparations. The of used to obtain control reduced by 7% 108 treated solely from start treatment when matched who had received insulins. 117 whose been changed bovine or bovine-porcine 9%. A further 511 receiving insulins were examined for local cutaneous subcutaneous abnormalities at injection sites. Lipoatrophy found 49 these (10%), but not insulin. results...

Diabetic ketoalkalosis: a readily misdiagnosed entityAn essential part of the treatment diabetic ketoacidosis.is replacement fluid and electrolytes.Though routine use alkali is questionable, it often used in early stages treatment.We describe two patients diagnosed as having ketoacidosis who were later found to have metabolic alkalosis.The these would been inappropriate potentially hazardous. Case reportsCase 1-A 24-year-old woman had treated with insulin for 11 years was admitted hospital...

Summary Eight patients suffering from primary hyperparathyroidism and diabetes mellitus are reported. All of the female. The clinical problems resulting co-existence these two endocrine disorders similarity their symptoms discussed. experience a large diabetic clinic population suggests that association with merits further investigation.

We report the case of a 56 year old male with hereditary haemochromatosis complicated by hepatic cirrhosis, insulin treated diabetes mellitus, hypogonadism and secondary hypothyroidism, latter which was corrected iron depletion. This is only second such to be reported.

S ummary . Three cases of eosinophilia, splenomegaly and cardiac disease are presented. Cases a similar nature have been reported in the literature question as to whether this syndrome is an eosinophil leukaemia or primary connective tissue disorder discussed.

Abstract Corporeality is an incipient theme in the scholarship of on-screen sound, and one with significant scope for additional investigation, coinciding argument that proclivity corporeal screen media has gathered momentum recent years. This article examines standout instances fleshly film sound titles like There Will Be Blood (2007) Under Skin (2013) via eros thanatos framework, evincing film’s enduring fixation provocative themes sex death. doublet instinctual drives borne classical...

Serial measurements of whole body potassium and nitrogen were carried out in 18 newly diagnosed diabetics. Initial made before treatment diabetes was commenced, further following the start treatment. Six patients required insulin remainder treated either with diet alone (four cases) or oral hypoglycaemic agents. Significant increases noted control diabetes. These changes most marked insulin. The techniques used for measurement offer considerable advantages over conventional metabolic balance...

Serial measurements of whole-body potassium were carried out in 28 diabetic patients, 23 whom diabetes had only recently been diagnosed. Eleven patients treated with insulin, 12 oral hypoglycaemic agents, and the rest already on agents developed poor control; four these required insulin. Whole-body was measured before treatment begun (or altered) again one six weeks later. (ratio observed to expected) initially reduced most requiring After control increased significantly three groups. The...

The effect of different periods fasting on oral glucose tolerance was investigated in 33 subjects. It found that deteriorated as the period became shorter. This seen almost exclusively subjects over 40 years age. Only blood sugar affected by duration pretest fast younger