Michael O’Callaghan

ORCID: 0000-0002-8450-186X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • Primary Care and Health Outcomes
  • COVID-19 Digital Contact Tracing
  • Privacy, Security, and Data Protection
  • Mobile Health and mHealth Applications
  • Bladder and Urothelial Cancer Treatments
  • Viral Infections and Vectors
  • Colorectal Cancer Screening and Detection
  • Global Cancer Incidence and Screening
  • Animal Disease Management and Epidemiology
  • Genetic factors in colorectal cancer
  • Renal cell carcinoma treatment
  • Multiple and Secondary Primary Cancers
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Healthcare Policy and Management
  • Colorectal Cancer Surgical Treatments
  • Child and Adolescent Health
  • Sexual function and dysfunction studies
  • Chronic Disease Management Strategies
  • Artificial Intelligence in Healthcare and Education
  • Colorectal Cancer Treatments and Studies
  • Virus-based gene therapy research
  • Medical Coding and Health Information
  • Evolution and Genetic Dynamics

The University of Adelaide
2018-2025

Flinders University
2018-2025

Flinders Medical Centre
2019-2025

University of Limerick
2013-2024

Cancer Australia
2024

Lyell McEwin Hospital
2023

Indiana University School of Medicine
2021

Centre for Cancer Biology
2019

Trinity College Dublin
2018-2019

Health Service Executive
2018

Although sexual dysfunction is a common treatment side-effect affecting men's quality of life, many prostate cancer patients do not receive or seek out treatments for erectile (ED). The aims this study are to investigate the extent and patterns use ED their perceived impact at different times following treatment. This retrospective cohort included all men on South Australian registry who completed one more Patient Reported Outcome Measures (PROMs) survey from 2016 2023 (n = 5561). Outcomes...

10.1186/s12894-025-01702-0 article EN cc-by BMC Urology 2025-01-31

In the last two decades, sex-related differences regarding cardiovascular diagnosis, treatment, and risk factors management have been reported. The current study aims to explore in outcomes among male female patients attending Irish secondary prevention programme - Heartwatch. This is a retrospective observational study. Anonymous data was extracted from Heartwatch database 2003 2017. Cardiovascular were analysed at sign-up four years follow-ups. An 8-point aggregate score (CCare Score)...

10.1016/j.ijcrp.2025.200376 article EN cc-by International Journal of Cardiology Cardiovascular Risk and Prevention 2025-02-14

Background Demand for GP services in the Republic of Ireland (RoI) is increasing, and resultant escalation workload demands an issue growing concern. Accordingly, accurate measurement description essential to inform future healthcare planning. Aim To provide a real-time with respect hours worked proportional time expenditure on typical activities. Design setting A prospective study among GPs RoI that took place from January 2019 March 2019. Method Participants were invited enrol by direct...

10.3399/bjgp20x710429 article EN cc-by British Journal of General Practice 2020-06-01

Objective To determine the utility of mild cognitive impairment (MCI) subtypes and number impaired domains on initial assessment at predicting progression to dementia in a sample memory clinic patients over 20‐year period. Methods A retrospective analysis was conducted those presenting with MCI from 1 January 1999 31 December 2018 inclusive. Those were broken down into one four using recommended cut‐off scores Cambridge Cognitive Assessment (CAMCOG). Binomial logistic regression used as...

10.1002/gps.5385 article EN International Journal of Geriatric Psychiatry 2020-08-04

Obese men have lower serum prostate-specific antigen (PSA) than comparably aged lean men, but the underlying mechanism remains unclear. The aim of this study was to determine effect obesity on PSA and potential contributing mechanisms. A cohort 1195 35 years over at recruitment, with demographic, anthropometric (BMI, waist circumference (WC)) hormone (serum testosterone, estradiol (E2)) hematology assessments obtained two waves assessed. Men a history prostate cancer or missing were...

10.1530/erc-17-0438 article EN Endocrine Related Cancer 2018-06-25

The biodistribution of AAVHSC7, AAVHSC15, and AAVHSC17 following systemic delivery was assessed in cynomolgus macaques (Macaca fascicularis). Animals received a single intravenous (IV) injection self-complementary AAVHSC-enhanced green fluorescent protein (eGFP) vector tissues were harvested at two weeks post-dose for anti-eGFP immunohistochemistry genome analyses. IV AAVHSC vectors produced widespread distribution eGFP staining glial cells throughout the central nervous system, with highest...

10.1371/journal.pone.0225582 article EN cc-by PLoS ONE 2019-11-26

Abstract Background: Contact tracing remains a critical part of controlling the spread COVID-19. Many countries have developed novel software applications (Apps) in an effort to augment traditional contact methods. Aim: To conduct national survey Irish population examine barriers and levers use App. Methods: Adult participants were invited respond via online weblink sent email messaging Apps posted on our university website popular social media platforms. Results: A total 8,088 responses...

10.21203/rs.3.rs-40778/v1 preprint EN cc-by Research Square (Research Square) 2020-07-10

Objective This study aims to gather public opinion on the Irish “COVID Tracker” digital contact tracing (DCT) App, with particular focus App usage, usability, usefulness, technological issues encountered, and potential changes App. Methods A 35-item online questionnaire was deployed for 10 days in October 2020, 3 months after launch of DCT Results total 2889 completed responses were recorded, 2553 (88%) respondents currently using Although four five users felt is easy download, use looks...

10.1177/20552076221085065 article EN cc-by-nc-nd Digital Health 2022-01-01

In July 2015, all children aged younger than 6 years gained free access to daytime and out-of-hours general practice services in the Republic of Ireland. Although 30% previously had access, 70% did not.To examine subsequent changes service use, we retrospectively analyzed anonymized visitation data from 8 practices North Dublin providing their local service, comparing 1 year before after introduction care.In granting care for years, 9.4% more attended 20.1% were seen services. Annual number...

10.1370/afm.2229 article EN The Annals of Family Medicine 2018-05-01

To explore the personal and/or medical reasons patients on active surveillance (AS) have, or consider having, further definitive treatment for their prostate cancer. Research suggests up to 50% of AS will discontinue within 5 years, though discontinuation from patient's perspective is under-explored.Prostate cancer who were had been at least 6 months recruited. A questionnaire assessed receiving/considering and extent which medical. Clinical information was extracted a state-level population...

10.1002/pon.5947 article EN cc-by-nc Psycho-Oncology 2022-05-11

DAO Diseases of Aquatic Organisms Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 54:1-14 (2003) - doi:10.3354/dao054001 A model spatially evolving herpesvirus epidemics causing mass mortality in Australian pilchard Sardinops sagax Alexander G. Murray1,2,*, Michael O¹Callaghan3, Brian Jones4 1Fisheries Research Services Marine Laboratory, Victoria Road, Torry, Aberdeen AB11 9DB, Scotland, United...

10.3354/dao054001 article EN Diseases of Aquatic Organisms 2003-01-01

Digital health technologies (DHTs), such as electronic records and prescribing systems, are transforming care delivery around the world. The quality of information in DHTs is key to safety care. We developed a novel clinical (CLIQ) framework assess DHTs.This study explored clinicians' perspectives on relevance, definition, assessment dimensions CLIQ framework.We used systematic iterative eDelphi approach engage clinicians who had governance roles or personal interest governance; were...

10.2196/41889 article EN cc-by Journal of Medical Internet Research 2022-11-17

Rural communities can experience more barriers to accessing health care than their urban counterparts, largely due fewer healthcare staff and services, geographical isolation. The purpose of this study is examine the availability GP practices in rural across Mid-West Ireland potential impact practice closure on patient access.

10.22605/rrh8843 article EN cc-by Rural and Remote Health 2024-10-21

To assess the therapeutic utility of AAVHSC15 and AAVHSC17, two recently described Clade F adeno-associated viruses (AAVs), seroprevalence neutralizing antibodies (NAbs) to these AAVs was assessed in a representative human population compared that AAV9. NAb levels were measured 100 unique sera different races (34, Black, 33 Caucasian, Hispanic) sex (49% female, 51% male) collected within United States. Fifty-six tested Huh7 cells 44 2V6.11 with vectors packaged either CMV-promoter upstream...

10.1089/humc.2017.239 article EN Human Gene Therapy Clinical Development 2018-03-01

Abstract Background There is a worldwide recruitment and retention crisis in general practice. Workforce planning has identified the need to train more practitioners as an urgent priority. Exposure of medical students practice part formal hidden curriculum, use longitudinal integrated clerkships, positive experiences role models are all thought be contributing factors doctors choosing careers Aim The aim this study was identify career destinations school graduates with 18-week clerkship...

10.1007/s11845-020-02260-0 article EN cc-by Irish Journal of Medical Science (1971 -) 2020-05-27
Coming Soon ...