A5087550619- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Neurological disorders and treatments
- Neuroscience and Neural Engineering
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Non-Invasive Vital Sign Monitoring
- Cardiomyopathy and Myosin Studies
- Heart rate and cardiovascular health
- Liver Disease and Transplantation
- Abdominal vascular conditions and treatments
- Diet and metabolism studies
- Nitric Oxide and Endothelin Effects
- Neurological and metabolic disorders
- Neuroscience of respiration and sleep
- Diabetes Management and Research
- Neuropeptides and Animal Physiology
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- EEG and Brain-Computer Interfaces
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetic Foot Ulcer Assessment and Management
Guy's and St Thomas' NHS Foundation Trust
2023-2024
St. Vincent's University Hospital
2015-2024
UCLA Health
2015-2022
University of California, Los Angeles
2015-2022
Texas Cardiac Arrhythmia
2015-2021
Committee on Publication Ethics
2017
Olive View-UCLA Medical Center
2015
Mater Misericordiae University Hospital
2012
Connolly Hospital Blanchardstown
2006-2012
Royal College of Surgeons in Ireland
2006-2008
Patients receive education before implantable cardioverter defibrillator (ICD) implantation. Patients' understanding of ICD therapy requires investigation.A retrospective cohort study was carried out at two implant centers where patients are educated during a consenting process pre-ICD Questionnaires examining were completed telephone interviews with ICDs.Of 75 interviewed, 62 (83%) male. The median age time implantation 64 years (standard deviation [SD] = 9.4; range: 29-82 years). interval...
Abstract Background Imbalances in the autonomic nervous system, namely, excessive sympathoexcitation, contribute to ventricular tachyarrhythmias. While thoracic epidural anesthesia clinically suppresses tachyarrhythmias, its effects on global and regional electrophysiology electrical wave stability have not been fully characterized. The authors hypothesized that attenuates myocardial excitability proarrhythmic of sympathetic hyperactivity. Methods Yorkshire pigs (n = 15) had an catheter...
Autonomic imbalance and excess sympathetic activity have been implicated in the pathogenesis of cardiovascular disease are targets for existing medical therapy. Neuromodulation may allow control projections to heart an on-demand reversible manner. This study provides proof-of-concept evidence that axonal modulation therapy (AMT) blocks sympathoexcitation by defining scalability, sustainability, memory properties AMT. Moreover, AMT directly reduces release myocardial norepinephrine, a...
Pulsed-field ablation (PFA) is a novel modality for pulmonary vein isolation in patients with atrial fibrillation (AF). We describe the initial uptake and experience of PFA using pentaspline catheter across selected National Health Service England (NHSE) centres.
The aims of this study were to examine human renal arteries and accurately characterize their sympathetic innervation location using CD-56 immunohistochemistry stains highlight Neural Cell Adhesion Molecules (N-CAM).Porcine models have often formed the basis for design denervation technology, with only a limited number studies available detail complex microarray nerves.Post-mortem (N = 14) harvested prepared into three sections (proximal, mid, distal), then stained Hematoxylin Eosin,...
Imbalances in the opposing actions of sympathetic and parasympathetic nerves controlling heart enhance risk for arrhythmia sudden cardiac death after myocardial infarction (MI). Plasticity peripheral neuron function may underlie observed changes cardiomotor nerve activity. We studied vagal control pigs chronic left ventricle. Stimulation cervical vagus produced greater bradycardic responses 8-weeks MI. Recordings epicardial electrocardiograms demonstrate increased severity duration...
The prevalence of lead failures is increasing with a growing population implantable cardioverter defibrillator (ICD) recipients. cost managing requires investigation.A retrospective cohort study patients requiring replacement for failure was performed. Details pertaining to admissions were recorded. per determined. Twenty-three {mean age [standard deviation (SD); range] = 56 (17; 18-83) years; 87% male} underwent at mean (SD; range) interval from implant 3.0 (1.8; 0.9-9.0) years. median...
Abstract With the increasing number of cardiac conduction devices (CCDs) insertions with various complexities in recent decades, it is crucial for clinicians (especially internal medicine residents and cardiologists) to have an up-to-date review current on chest radiograph. Chest X-ray remains most cost-effective accessible imaging modality assess device position its associated complications, not only immediately after insertion but also during follow-up visit as outpatient. Various types...
Predictors of left ventricular dysfunction with right pacing: Is paced QRS duration the answer?