- Innovations in Medical Education
- Global Health Workforce Issues
- Hospital Admissions and Outcomes
- Diversity and Career in Medicine
- Congenital heart defects research
- Developmental Biology and Gene Regulation
- Clinical Reasoning and Diagnostic Skills
- Global Health and Surgery
- Patient Satisfaction in Healthcare
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Healthcare Policy and Management
- Medical Education and Admissions
- Tissue Engineering and Regenerative Medicine
- Genomics and Chromatin Dynamics
- Primary Care and Health Outcomes
- Nursing Roles and Practices
- Animal Vocal Communication and Behavior
- Cephalopods and Marine Biology
- Silk-based biomaterials and applications
- Radiology practices and education
- Primate Behavior and Ecology
- Plant Molecular Biology Research
- Modular Robots and Swarm Intelligence
- Patient-Provider Communication in Healthcare
- Periodontal Regeneration and Treatments
University of Minnesota Medical Center
2017-2024
Tottori University
2022-2024
Gakushuin University
2023
University of Minnesota
2022
Hiroshima University
2022
University of Pittsburgh
2019
Tohoku University
2014-2017
Johns Hopkins Bayview Medical Center
2011-2016
Johns Hopkins University
2011-2016
Abstract Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One these magnificent examples transition from non-avian dinosaurs to birds that has created numerous evolutionary innovations such as self-powered flight and its associated wings with feathers. By analysing 48 bird genomes, we identified millions avian-specific highly conserved elements (ASHCEs) predominantly (>99%) reside in non-coding regions. Many ASHCEs show...
ABSTRACT The 5′Hox genes play crucial roles in limb development and specify regions the proximal-distal axis of limbs. However, there is no direct genetic evidence that Hox are essential for non-mammalian tetrapods or regeneration. Here, we produced single to quadruple Hox13 paralog mutants using CRISPR/Cas9 system newts (Pleurodeles waltl), which have strong regenerative capacities, also germline mutants. We show digit formation development, as mice. In addition, Hoxa13 has a predominant...
To develop and validate a new inpatient satisfaction metric to assess patients' perceptions of hospitalist performance.We developed the Tool Assess Inpatient Satisfaction with Care from Hospitalists (TAISCH) by building upon theoretical underpinnings quality care measures that Society Hospital Medicine endorses. TAISCH was completed inpatients at an academic institution between September 2012 December after they had been cared for same provider least 2 consecutive days. Content, internal...
Abstract Introduction Due to the large language and cultural distances between Japan US compared many countries, Japanese International Medical Graduates (IMGs) may have a different training experience, including more stress, than IMGs. We examined clinical experience for IMGs, challenges encountered, how those are overcome, benefits of training. Methods performed individual semistructured interviews with 35 purposively sampled IMGs who had completed Exploratory thematic analysis was...
Abstract BACKGROUND: Hospital Medicine is growing rapidly, and the number of physician assistants (PAs) in this field expected to grow. However, there no available data related learning needs PA hospitalists. OBJECTIVE: To conduct a assessment for hospitalists who may be embarking on hospitalist career. DESIGN: Cross‐sectional survey based Core Competencies Medicine. SETTING/PARTICIPANTS: A sample PAs working United States. MEASUREMENTS: Amount experience with core diagnoses procedures,...
Background : The organizing center, which serves as a morphogen source, has crucial functions in morphogenesis animal development. center is necessarily located certain restricted area the morphogenetic field, and there are several ways an can be restricted. for limb morphogenesis, ZPA (zone of polarizing activity), specifically expresses Shh gene to posterior region developing bud. Results pre‐pattern along anteroposterior axis, provided by anterior Gli3 expression Hand2 expression, seems...
Background: International Medical Graduates (IMGs) are commonly understood to move from low high resource countries with motivations including improved financial situations and cultures of emigration. A presumable exception the above themes would be Japanese IMG population. The aim this study was develop an understanding experience.Methods: Using a grounded theory approach, we interviewed 19 IMGs working in US 16 Japan who had completed clinical training. Questions addressed decision-making...
The clinical collaborations among hospitalist physicians create opportunities for peer evaluation. We conducted this study to generate validity evidence a scale that allows assessment of professional performance.All the working >1 year at our hospital were asked assess each their physician colleagues along eight domains and name three whom they would choose care loved one needing hospitalization. A mean composite performance score was generated provider. Statistical analyses using Pearson...
ABSTRACT Background International medical graduates (IMGs) have significant exposure to clinical training in their home country, which provides opportunity for international comparison of experiences. One relevant IMG population is Japanese physicians who completed some before entering residency programs the United States and desire improve education Japan. Objective We examined IMGs' perceptions respective attributes Methods Individual semistructured interviews were conducted with 33...
Investigators sought to clarify the characteristics of students' self-identified learning goals.Goals collected from two schools were categorized into content themes and as "specific" or "general" qualitatively. Associations between learner distributions goals analyzed quantitatively.Investigators obtained 879 290 students. Clinical skills most frequently identified (89%), followed by medical knowledge (44%), career choice (17%), attitudinal (15%). Within clinical skills, 12 subcategories...
Phenomenon: Internationally, efforts to produce an adequate supply of effective generalist physicians commonly encounter resistance. Achieving reform requires changes in educational and clinical practice cultures, clinician educators play a central role championing change. In Japan, training fields has historically been lacking, but for decades the government advocated alignment with Western models. Meanwhile, some Japanese have pursued U.S. intention help change education systems back...
Physicians have been shown to possess limited ability for accurate self-assessment; thus, effective feedback is crucial their professional development. This study describes providers' reflections on data and evaluates the hospitalist physicians' impressions about receiving this derived from a new survey metric specifically designed obtain patient assessment of treating provider coupled with reflective sessions.Participants were 26 hospitalists one institution. These used development...
Abstract Introduction Entering US clinical training requires completing requirements and navigating an application process differing from the Japanese system. Additionally, increases to number of medical school graduates have increased competition for residency positions. We examined profiles International Medical Graduates (IMGs) who completed training, timelines securing positions, greatest challenges during this methods overcome them. Methods Individual semistructured interviews were...
Abstract Amphibians and fish often regenerate lost parts of their appendages (tail, limb, fin) after amputation. Limb regeneration in adult amphibians provides an excellent model for appendage (limb) through 3D morphogenesis along the proximodistal, dorsoventral, anteroposterior axes mammals, because limb is a homologous organ among mammals. However, manipulating gene expression specific remains difficult; this turn hinders elucidation molecular mechanisms underlying regeneration. To address...
Abstract 5′ Hox genes regulate pattern formation along the axes of limb. Previously, we showed that Hoxa13/Hoxd13 double‐mutant newts lacked all digits forelimbs during development and regeneration, showing newt Hox13 is necessary for digit in regeneration. In addition, found another unique phenotype. Some crispant hindlimb defects, which whole or almost hindlimbs were lost, suggesting a novel function limb development. Using germline mutants, mutation led to defects. The buds crispants...
Abstract 5’ Hox genes regulate pattern formation along the axes of limb. Previously, we showed that Hoxa13/Hoxd13 double mutant newts lacked all digits forelimbs during development and regeneration, showing newt Hox13 is necessary for digit in regeneration. In addition, found another unique phenotype. A part crispant hindlimb defects, which whole or almost hindlimbs were lost, suggesting a novel function limb development. Using germline mutants, mutation led to defects. The buds crispants...
Abstract Previous studies indicated the importance of reciprocal interactions between residual tissues in stump and newly formed blastema for achieving functional joint regeneration after amputation at level newts. This interaction during was named “reintegration”. When this reintegration mechanism evoked Xenopus leavis , a induced frogs. Interestingly, degradation extracellular matrix (ECM) remaining cartilage observed both newts Histological gene expression analyses suggested that Type II...
By 2014, there were more than 40,000 hospitalists delivering the majority of inpatient care in US hospitals. No empiric research has characterized hospitalist comportment and communication patterns as they for patients.The chiefs hospital medicine at five different hospitals asked to identify their best hospitalists. These watched during routine clinical patients. An observation tool was developed that focused on elements believed be associated with excellent communication. One observer...