The present study aimed to analyze the effects of addition blood phycogenic bone substitute Algipore(®) on severity in vivo tissue reaction. Initially, Fourier-transform infrared spectroscopy (FTIR) was conducted its chemical composition. subcutaneous implantation model Balb/c mice then applied for up 30 d reactions basis specialized histochemical, immunohistochemical, and histomorphometrical methods. data FTIR analysis showed that material is mainly composed hydroxyapatite with some...

We analyzed the influence of inflammatory macrophages on osteogenic process in subcutaneous implants composed mineral bone substitute. Thioglycollate-elicited peritoneal (TEPMs) were characterized as inflammatory. This was confirmed microscopically by nitroblue tetrazolium (NBT) test and production tumor necrosis factor ? (TNF-?). The (M-type) made substitute (Bio-Oss?) mixed with TEPMs blood clot. Implants without served control (C-type). Subcutaneous implantation interscapular area...

The iron deficiency anemia is particularly common in reproductive age women. Thus, it important to explore facts of knowledge about importance nutrition female population. study included 176 respondents and collection data was done using a questionnaire statistically analyzed. Women from rural area, women younger groups pregnant showed higher level nutrition. most were the normal weight range, but significant prevalence inadequate intakes determined (daily average intake for 7.62 mg/day)...

Vascular development has a great significance in the osteogenic process and bone tissue engineering (BTE). BTE is based on various combinations of three principal types components: biomaterials as scaffolds, regulatory signals cells. The aim our study was to evaluate, at gene expression histological level, effect triad components vascularization an ectopic bone-forming model mice. Bone mineral matrix (BMM) used scaffold carrier, platelet-rich plasma (PRP) source adipose stem cells (ASCs) for...

Vascularization and osteogenesis in ectopically implanted bone tissue-engineered constructs with endothelial osteogenic differentiated adipose-derived stem cells

Simulated body fluid (SBF) is an artificial which has ionic composition and concentration similar to human blood plasma. Purpose This paper compares the interaction between nanomaterial containing calcium phosphate/poly-DL-lactide-co-glycolide (N-CP/PLGA) SBF, in order investigate whether what extent inorganic of plasma leads aforementioned changes material. Methods N-CP/PLGA was incubated for 1, 2, 3, 5 weeks SBF. The surface material analyzed on SEM-EDS FTIR spectrometer, while SBF...

Abstract Biphasic calcium phosphate (BCP) materials are widely employed as bone substitute due to their resorption/degradation properties. Inflammation after implantation of such represents a prerequisite for tissue repair and regeneration but can be also problematic if it is not only transient followed by fibrosis scarring. Here, we modified BCP covalently with hyaluronan (HA) heparin (Hep), glycosaminoglycans that possess anti‐inflammatory Beside the characterization particle surface...

Bone tissue deficiencies can be caused by fractures, bone loss or tumors.Insufficient vascularization is the main problem in successful regeneration.In order to improve during regeneration, a promising methods have been developed field of engineering (BTE) using adipose-derived stem cells (ADSCs).The aim this study was examine vasculogenic potential ADSCs vitro induced into osteoblasts (OBs) combined with platelet-rich plasma (PRP) and mineral matrix (BMM) ectopic osteogenic implants,...

The purpose of biomaterials is to replace a part or function the body in safe, physiologically and economically acceptable way.The process reconstruction bone defects has always been big problem orthopedics maxillofacial surgery.Since hydroxyapatite (HAp) was detected as component, predominant constituent integral element Mammalian bones, development phospate ceramics potential materials for implantation enabled.This study investigated whether which way biomaterial calcium...

This study examines the concentration of essential minerals and toxic heavy metals in acacia honey samples collected Serbia, highlighting their health implications environmental influences. Among 23 elements analyzed, calcium levels ranged from 38.35 to 1148.5 mg/kg, averaging 411.5 higher than previous findings for honey, underscoring its nutritional value. Potassium averaged 208 consistent with literature, whereas Na content was notably values reported literature. Zinc were typical...

Repair of bone defects can be supported by appropriate biomaterials, cells and regulatory signals, which is the basic principle tissue engineering. The components marrow blood clot come in close contact with after injury. Since these structures represent source different cell types we wanted to examine their effect on osteoreparatory process ectopic implants. Subcutaneous implantation was performed male Balb/c mice. Bio-Oss® biomaterial function mineral matrix carrier loaded diluted...

Regenerative medicine (RM) exploits the innate potential of human body to effectively repair and regenerate damaged tissues organs with help various biomaterials. Tissue engineering (TE) makes it possible replace new ones. Research in field biomaterials has significantly improved area RM TE. Biomaterials are used as orthopedic, dental, cardiovascular implants, medical devices, fields reconstructive regenerative medicine, among others. Important preconditions for biomaterial be implantation...

Simulated body fluid (SBF) is an artificial which has ionic composition and concentration similar to human blood plasma.PurposeThis paper compares the interaction between nanomaterial containing calcium phosphate/poly-DL-lactide-co-glycolide (N-CP/PLGA) SBF, in order investigate whether what extent inorganic of plasma leads aforementioned changes material.MethodsN-CP/PLGA was incubated for 1, 2, 3, 5 weeks SBF. The surface material analyzed on SEM-EDS FTIR spectrometer, while SBF subjected...

Honey has long been recognized as a special natural product, not only because of its nutritional value, but also healing properties.Although it is mostly composed carbohydrates, contains numerous enzymes, amino acids, organic polyphenols, minerals, vitamins and other substances, whose presence varies depending on the type honey botanical geographical origin.Thanks to antimicrobial properties, well beneficial effect wound healing, tissue repair regeneration, could have potential role in...

Considering the properties of water and benzene molecules, one can expect very different benzene/benzene water/water interactions. Benzene does not have a dipole moment, while does. Analysis data in crystal structures Cambridge Structural Database (CSD) revealed most frequent geometries. The majority interactions CSD are stacking with large horizontal displacements, geometries that minima on potential surface. A number contacts hydrogen bonds, 70% all attractive In addition, two forming...