Hao Zhang

ORCID: 0000-0002-4016-0717
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About
Contact & Profiles
Research Areas
  • Piperaceae Chemical and Biological Studies
  • Computational Drug Discovery Methods
  • Ginger and Zingiberaceae research
  • Phytochemical compounds biological activities
  • Reproductive tract infections research
  • Pediatric health and respiratory diseases
  • Liver Disease and Transplantation
  • Antimicrobial Peptides and Activities
  • Health, psychology, and well-being
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Drug-Induced Hepatotoxicity and Protection

Anhui University of Traditional Chinese Medicine
2024

Southern Medical University
2021

Affiliated Hospital of Southwest Medical University
2020

In this study, kaempferol (KA) ameliorates APAP-induced hepatotoxicity by activating HO-1/NQO1 and inhibiting HMGB1/TLR4/NF-κB signaling NLRP3 inflammasome activation.

10.1039/d0fo00724b article EN Food & Function 2020-01-01

Abstract: Objective: To explore the target of anti-knee osteoarthritis (KOA) in effective chemical compounds piper longum L based on network pharmacological methods. Methods : The active were collected employing database retrieval TCMSP, TCM-PTD, and literature mining. Swiss Target Prediction service predicts targets compounds, at same time, drugs treating knee by retrieving OMIM CTD databases. subjected to an alignment analysis screen out piperine we simulated binding sites vivo proteins...

10.26434/chemrxiv.12388997.v1 preprint EN cc-by-nc-nd 2020-06-01

<p><b>Abstract:</b><b></b></p><p><b><i>Objective:</i></b> To explore the target of anti-knee osteoarthritis (KOA) in effective chemical compounds piper longum L based on network pharmacological methods.<b></b></p><p><b><i>Methods</i></b>: The active were collected employing database retrieval TCMSP, TCM-PTD, and literature mining. Swiss Target Prediction service predicts targets...

10.26434/chemrxiv.12388997 preprint EN cc-by-nc-nd 2020-06-01
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