Stephen B. R. E. Brown

ORCID: 0000-0002-4023-4843
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Neural and Behavioral Psychology Studies
  • Emergency and Acute Care Studies
  • Action Observation and Synchronization
  • Neural dynamics and brain function
  • Memory and Neural Mechanisms
  • EEG and Brain-Computer Interfaces
  • Homelessness and Social Issues
  • Motor Control and Adaptation
  • Olfactory and Sensory Function Studies
  • Heart Rate Variability and Autonomic Control
  • Behavioral and Psychological Studies
  • Healthcare Policy and Management
  • Geriatric Care and Nursing Homes
  • Pharmaceutical studies and practices
  • Epilepsy research and treatment
  • Creativity in Education and Neuroscience
  • Cardiovascular and exercise physiology
  • Employment and Welfare Studies
  • Child and Animal Learning Development
  • Hemoglobinopathies and Related Disorders
  • Decision-Making and Behavioral Economics
  • Neuroscience, Education and Cognitive Function
  • Mental Health Treatment and Access
  • Clinical Reasoning and Diagnostic Skills
  • Hospital Admissions and Outcomes

Red Deer College
2020-2023

University of Illinois Hospital & Health Sciences System
2013-2021

Leiden University
2011-2020

Salford Royal Hospital
2020

Northern Health and Social Care Trust
2019-2020

University of Illinois Chicago
1993-2018

Moscow Institute of Thermal Technology
2018

University of California, San Francisco
2017

Corewell Health Butterworth Hospital
2013

Corewell Health Blodgett Hospital
2013

ORIGINAL RESEARCH article Front. Hum. Neurosci., 27 February 2012Sec. Sensory Neuroscience Volume 6 - 2012 | https://doi.org/10.3389/fnhum.2012.00033

10.3389/fnhum.2012.00033 article EN cc-by Frontiers in Human Neuroscience 2012-01-01

Applying the science of networks to quantify discriminatory impact ICD-9-CM ICD-10-CM transition between clinical specialties.Datasets were Center for Medicaid and Medicare Services mapping files, general equivalence mappings, statewide emergency department billing. Diagnoses represented as nodes their mappings directional relationships. The complex network was synthesized an aggregate simpler motifs tabulation per specialty.We identified five motif categories: identity, class-to-subclass,...

10.1136/amiajnl-2012-001358 article EN Journal of the American Medical Informatics Association 2013-05-06

Abstract Researchers have proposed several hypotheses about the neuromodulator systems involved in generating P3 components of ERP. To test some these hypotheses, we conducted a randomized placebo‐controlled crossover study which investigated how late positive ERP response to deviant stimuli is modulated by (a) clonidine, an α 2 agonist that attenuates baseline noradrenergic activity; and (b) scopolamine, muscarinic antagonist acetylcholine receptors. We collected EEG data from 18 healthy...

10.1111/psyp.12544 article EN Psychophysiology 2015-09-09

To make optimal predictions in a dynamic environment, the impact of new observations on existing beliefs—that is, learning rate—should be guided by ongoing estimates change and uncertainty. Theoretical work has proposed specific computational roles for various neuromodulatory systems control rate, but empirical evidence is still sparse. The aim current research was to examine role noradrenergic cholinergic rate regulation. First, we replicated our recent findings that centroparietal P3...

10.1162/jocn_a_01317 article EN Journal of Cognitive Neuroscience 2018-07-31

Electrophysiological studies have identified a scalp potential, the late positive potential (LPP), which is modulated by emotional intensity of observed stimuli. Previous work has shown that LPP reflects modulation activity in extrastriate visual cortical structures, but little known about source modulation. The present study investigated whether beta-adrenergic receptors are involved generation LPP. We used genetic individual differences approach (experiment 1) and pharmacological...

10.1007/s00213-011-2426-x article EN cc-by-nc Psychopharmacology 2011-08-17

An increasing number of empirical phenomena that were previously interpreted as a result cognitive control, turn out to reflect (in part) simple associative-learning effects. A prime example is the proportion congruency effect, finding interference effects (such Stroop effect) decrease incongruent stimuli increases. While this was regarded strong evidence for global conflict monitoring-cognitive control loop, recent has shown effect largely item-specific and hence must be due associative...

10.3389/fnhum.2014.00023 article EN cc-by Frontiers in Human Neuroscience 2014-01-01

People usually respond faster to a visual stimulus when it is immediately preceded by task-irrelevant, auditory accessory (AS). This AS effect occurs even in choice reaction time tasks, despite the fact that carries no information about correct response. Researchers often assume mediated phasic arousal burst evoked AS, but direct evidence for assumption lacking. We conducted pupillometry study directly test hypothesis. Participants carried out demanding task with stimuli occurring on 25% of...

10.1111/psyp.12653 article EN Psychophysiology 2016-04-20

An intense but task-irrelevant auditory accessory stimulus that is presented almost simultaneously with a visual imperative can reduce reaction times (RTs) to stimulus. The information-processing locus and neural underpinnings underlying this phasic alerting effect are still poorly understood. authors investigated possible noradrenergic or cholinergic basis of the in double-blind pharmacological study (N = 18), which healthy participants received single dose clonidine (an α2-adrenergic...

10.1037/bne0000030 article EN Behavioral Neuroscience 2015-01-26

The specific role of neuromodulator systems in regulating rapid fluctuations attention is still poorly understood. In this study, we examined the effects clonidine and scopolamine on multiple target detection a serial visual presentation task to assess central noradrenergic cholinergic temporal attention. Eighteen healthy volunteers took part crossover double-dummy study which they received (150/175 μg), (1.2 mg), placebo by mouth counterbalanced order. A dual-target attentional blink was...

10.1007/s00213-015-4111-y article EN cc-by Psychopharmacology 2015-10-28

The P3 is a ubiquitous component of stimulus-driven neural activity that can be observed in scalp electrophysiological recordings. Multiple lines evidence suggest an important role for the noradrenergic system generation P3. However, pharmacological studies using manipulations have so far been limited to agents affect α2-receptor signaling. present study investigated whether β-adrenergic receptors are involved and error positivity (Pe), event-related potential elicited by errors bears many...

10.1007/s00213-015-3966-2 article EN cc-by Psychopharmacology 2015-07-03

The Stroop task is a popular neuropsychological test that measures executive control. Strong interference commonly interpreted in neuropsychology as diagnostic marker of an impairment control, possibly reflecting dysfunction. However, models the indicate several other aspects colour and word processing may also account for individual differences task, independent Here we use new approaches to investigate degree which correlate with relative speed stimuli, lateral inhibition between visual...

10.3389/fpsyg.2016.00822 article EN cc-by Frontiers in Psychology 2016-05-31

Frequent or chronic reduction in heart rate variability (HRV) is a powerful predictor of cardiovascular disease, and psychological stress has been suggested to be co-determinant this reduction. Recently, we evaluated various methods measure additional HRV everyday life relate these reductions stress. In the current paper, thoroughly evaluate add two new both newly-acquired reanalyzed datasets. All use subset 24 hours' worth movement data do so: either first 10 minutes every hour, full hours,...

10.3389/fnins.2020.564123 article EN cc-by Frontiers in Neuroscience 2020-10-22

Abstract Background : The 14 neighborhoods surrounding University of Chicago Hospitals (UCH) have both Chicago's highest “ambulatory-care-sensitive condition” hospitalization rates and lack community-based care. To address these problems, in 2004, the Southside Medical Homes (SMH) Network began linking emergency department (ED) patients with 18 community providers. ED-based patient navigator (patient advocate) is an integral component this network, their current developing roles will be...

10.1017/s1049023x00065018 article EN Prehospital and Disaster Medicine 2008-06-01

Objective The Paediatric Admission Guidance in the Emergency Department (PAGE) score is an assessment tool currently development that helps predict hospital admission using components including patient characteristics, vital signs (heart rate, temperature, respiratory rate and oxygen saturation) clinical features (eg, breathing, behaviour nurse judgement). It aims to assist safe discharge decision making environments such as emergency departments urgent care centres. Determining inter-rater...

10.1136/archdischild-2019-318664 article EN cc-by Archives of Disease in Childhood 2020-09-28
Coming Soon ...