A5080345311- Olfactory and Sensory Function Studies
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Head and Neck Cancer Studies
- Long-Term Effects of COVID-19
- Obstructive Sleep Apnea Research
- Tracheal and airway disorders
- Cancer Immunotherapy and Biomarkers
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Vestibular and auditory disorders
- Inflammatory Biomarkers in Disease Prognosis
- Essential Oils and Antimicrobial Activity
University of Trieste
2021-2025
TU Dresden
2022
Azienda Sanitaria Universitaria Integrata di Trieste
2022
Abstract This study prospectively assessed the 6-month prevalence of self-reported and psychophysically measured olfactory dysfunction in subjects with mild-to-moderate COVID-19. Self-reported smell or taste impairment was evaluated by SNOT-22 at diagnosis, 4-week, 8-week, 6-month. At 6 months from psychophysical evaluation function also performed using 34-item culturally adapted University Pennsylvania Smell Identification Test (CA-UPSIT). 145 completed both subjective evaluation. According...
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can cause a wide array of symptoms ranging from mild to severe or fatal forms coronavirus disease 2019 (COVID-19).1 Furthermore, it has been observed that in proportion patients variable range may persist for long time.2 An increasing number studies have focused on COVID, but they mainly concentrated previously hospitalized COVID-19 reporting up 6-months after illness.3, 4 The main aim this study was evaluate the...
The aim of the present study was to estimate 1 year prevalence and recovery rate self-reported chemosensory dysfunction in a series subjects with previous mild-to-moderate symptomatic COVID-19.Prospective based on SNOT-22, item "sense smell or taste" additional outcomes.268/315 patients (85.1%) completing survey at baseline also completed follow-up interview. 12 months COVID-19 associated 21.3% (95% CI 16.5-26.7%). Of 187 who complained baseline, 130 (69.5%; 95% 62.4-76.0%) reported complete...
COVID-19-related persistent olfactory dysfunction (OD) presents remarkable interindividual differences, and little is known about the host genetic factors that are involved in its etiopathogenesis. The goal of this study was to explore underpinning OD through analysis Whole Genome Sequencing data 153 affected subjects, focusing on genes antiviral response regulation. An innovative approach developed, namely assessment association between a "gene score", defined as ratio number homozygous...
Olfactory and gustatory dysfunctions are among the most commonly self-reported symptoms of COVID-19, with a substantial fraction patients still reporting them after acute phase disease. 1,2A body evidence has demonstrated effect severe respiratory syndrome coronavirus 2 (SARS-CoV-2) on olfaction, 3 although few observations exist regarding direct involvement virus in pathogenesis impairment. 4hile correlation between olfactory function psychophysical tests been extensively analyzed, showing...
Abstract Background In a proportion of patients recovered from the acute COVID-19 phase, variable range symptoms has been observed to persist for at least 6-months. Objectives The main aim this study was evaluate prevalence COVID-related 12-months after onset mild-to-moderate disease. Methods Prospective based on structured questionnaires and additional outcomes. Results 304/354 completing survey baseline also completed follow-up interview (85.9%; median [range] age, 47 [18-76] years; 185...
Abstract Background Inflammatory blood markers have been associated with oncological outcomes in several cancers, but evidence for head and neck squamous cell carcinoma (HNSCC) is scanty. Therefore, this study aims at investigating the association between five different inflammatory outcomes. Methods This multi-centre retrospective analysis included 925 consecutive patients primary HPV-negative HNSCC (median age: 68 years) diagnosed April 2004 June 2018, whose pre-treatment parameters were...
Abstract Purpose The aim of the present study was to estimate one-year prevalence and recovery rate self-reported chemosensory dysfunction in a series subjects with previous mild-to-moderate symptomatic COVID-19. Methods Prospective based on SNOT-22 (item sense smell or taste) additional outcomes. Results 268/315 patients (85.1%) completing survey at baseline also completed follow-up interview. 12-months COVID-19 associated 21.3% (95% CI: 16.5-26.7%). Of 187 who complained baseline, 130...
Abstract Objectives The sense of smell is important as a warning system, in social communication and guiding food intake. Impairment common, cases are increasing following COVID‐19. Olfactory dysfunction may lead to decreased quality life. There several established ways assess olfaction including the “Sniffin’ Sticks” which validated test for healthy diseased populations. Methods odor threshold traditionally determined using single staircase procedure, with narrow or wide step. We...