A5087790811- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Heart Rate Variability and Autonomic Control
- Stress Responses and Cortisol
- Sex and Gender in Healthcare
- Child Abuse and Trauma
- Treatment of Major Depression
- Neural dynamics and brain function
- Action Observation and Synchronization
- Mental Health Treatment and Access
- LGBTQ Health, Identity, and Policy
- Schizophrenia research and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroendocrine regulation and behavior
- Attention Deficit Hyperactivity Disorder
- Epilepsy research and treatment
Virginia Tech
2022-2024
University of Pittsburgh
2020-2023
Cognitive control is of great interest to researchers and practitioners. The concurrent association between family socioeconomic status (SES) adolescent cognitive well-documented. However, little known about whether how SES relates individual differences in the development control. current four-year longitudinal investigation (N = 167, 13-14 years at Wave 1) used multi-source interference task performance (reaction time correct trials minus neutral trials) corresponding neural activities...
The use of functional neuroimaging has been an extremely fruitful avenue for investigating the neural basis human reward function. This approach included identification potential neurobiological mechanisms psychiatric disease and examination environmental, experiential, biological factors that may contribute to risk via effects on system. However, a central largely unexamined assumption much this research is function individual difference characteristic relatively stable trait-like over time.
Anhedonia emerges during adolescence and is characteristic of severe mental illness (SMI). To understand how anhedonia emerges, changes with time, relates other symptoms, there a need to patterns this symptom's course reflecting change or stability-and associations clinical symptoms neural reward circuitry in adolescents at risk SMI. In total, 113 low high familial developing SMI completed measures up five time points across 2 years functional magnetic resonance imaging scanning guessing...
Socioecological factors such as family environment and parenting behaviors contribute to the development of substance use. While biobehavioral synchrony has been suggested foundation for resilience that can modulate environmental effects on development, role brain similarity attenuates deleterious contexts not clearly understood. We tested whether parent-adolescent neural similarity—the level pattern between functional connectivity representing attunement within each dyad—moderates...
Abstract Introduction Emotions typically emerge in interpersonal contexts, but the neural circuitry involved remains insufficiently understood. Two key features of contexts are interactions (e.g., supportive physical touch serving as a form social regulation) and traits. Social regulation research has predominately focused on fear by using threat (i.e., electric shock) stimulus. Given that helps with various negative emotions real world, visual stimuli elicit more broadly would also be...
Abstract Neuroscience research underscores the critical impact of adverse experiences on brain development. Yet, there is limited understanding specific pathways linking to accelerated or delayed development and their ultimate contributions psychopathology. Here, we present new longitudinal data demonstrating that neurocognitive functioning during adolescence, as affected by experiences, predicts psychopathology young adulthood. The sample included 167 participants (52% male) assessed in...
Greater neural similarity between parents and adolescents may reduce adolescent substance use. Among 70 parent-adolescent dyads, we tested a longitudinal path model in which family economic environment is related to use, directly indirectly through parental monitoring. Neural was measured as pattern functional brain connectivity at Time 1. Parents reported socioeconomic status monitoring Adolescents 1 use 2. Higher associated with greater similarity. lower mediated adolescent-perceived...
Abstract Objective To test the hypothesis that depression is associated with differential neurodevelopment of reward circuitry in adolescence. Methods Adolescent girls (N=183, 58 MDD early or late adolescence) underwent MRI scans from ages 16-20 (1-4 scans/participant, 477 total) and completed a card-guessing fMRI task monetary rewards. Mixed-effect models tested effect age moderating on whole-brain regional activation during anticipation. Results Eighty 414 regions showed effects (p FDR...
Abstract Background The use of functional neuroimaging has been an extremely fruitful avenue for investigating the neural basis human reward function. This approach included identification potential neurobiological mechanisms psychiatric disease and examination environmental, experiential, biological factors that may contribute to risk via effects on system. However, a central largely unexamined assumption much this research is function individual difference characteristic relatively stable...
Hedonic dysregulation is evident in addiction and substance use disorders, but it not clearly understood how hedonic processes may interact with brain development related to cognitive control influence risky decision making during adolescence. The present study used prospective longitudinal data clarify the role of link between experiences Participants included 167 adolescents (53% male) assessed at four time points, annually. Adolescents participated a functional magnetic resonance imaging...
Childhood adversity and depression have been linked with heightened inflammation. However, few longitudinal studies examine how dimensions of maltreatment (i.e., abuse neglect) differentially impact pathways to inflammation internalizing symptoms. The present study examined effects neglect on (1) symptoms through inflammation, (2) across 3 years adolescence in the context COVID-19 pandemic. In a sample 78 adolescents, significant indirect revealed that childhood abuse, not neglect,...