Seika Sai

ORCID: 0000-0002-4066-988X
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About
Contact & Profiles
Research Areas
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Nutrition and Health in Aging
  • Cardiac Imaging and Diagnostics
  • Diabetes Treatment and Management
  • Frailty in Older Adults
  • Dialysis and Renal Disease Management
  • Congenital Heart Disease Studies
  • Hemodynamic Monitoring and Therapy
  • Electrolyte and hormonal disorders
  • Peptidase Inhibition and Analysis
  • IL-33, ST2, and ILC Pathways
  • Acute Kidney Injury Research
  • Renal and Vascular Pathologies
  • Coronary Artery Anomalies
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Aortic Disease and Treatment Approaches
  • Cardiovascular and Diving-Related Complications
  • Pancreatic function and diabetes
  • Body Composition Measurement Techniques
  • Pulmonary Hypertension Research and Treatments
  • Ferrocene Chemistry and Applications
  • Salivary Gland Tumors Diagnosis and Treatment
  • Air Quality and Health Impacts

University of Alberta
2025

Hitachi General Hospital
2016-2022

University of Tsukuba
2015-2019

Comprehensive Cardiovascular
2018

Background: Although 2-dimensional strain analyses based on speckle tracking echocardiography have been used to detect myocardial deformation, the prognostic impact of is unclear in patients with acute decompensated heart failure (HF). We investigated whether left ventricular and right (RV) parameters assessed by provide incremental information hospitalized because HF. Methods Results: Six hundred eighteen (age, 72±13 years; 38% women; ejection fraction, 46±16%) for HF underwent clinical...

10.1161/circimaging.117.007249 article EN Circulation Cardiovascular Imaging 2018-10-01

Abstract Aims The objective of the study was to evaluate whether geriatric nutritional risk index (GNRI) at discharge may be helpful in predicting long‐term prognosis patients hospitalized with heart failure (HF) preserved ejection fraction (HFpEF, left ventricular ≥50%), a common HF phenotype elderly. Methods and results Overall, 110 elderly HFpEF (≥65 years) from Ibaraki Cardiovascular Assessment Study‐HF ( n = 838) were enrolled. mean age 78.5 ± 7.2 years, male accounted for 53.6% 59)....

10.1002/ehf2.12405 article EN cc-by-nc-nd ESC Heart Failure 2019-02-01

Background and Purpose: Thrombolysis can improve outcome in patients with acute ischemic stroke. However, recanalization is not always complete persisting cerebral vascular occlusion >50% of despite treatment. Properties the formed thrombus may influence thrombolysis efficiency impede success. Here we examine whether differences thrombin generation are associated unfavourable treated Methods: Two cohorts stroke were recruited (cohort 1 n=36 patients, cohort 2 n= 42). Thrombin was...

10.1161/str.56.suppl_1.wmp118 article EN Stroke 2025-01-30

Controlling nutritional status (CONUT) uses 2 biochemical parameters (serum albumin and cholesterol level), 1 immune parameter (total lymphocyte count) to assess status. This study examined if CONUT could predict the short-term prognosis of heart failure (HF) patients.

10.1536/ihj.17-073 article EN International Heart Journal 2018-01-01

Left ventricular diastolic dysfunction (LVDD) has prognostic significance in heart failure (HF). We aimed to assess the impact of LVDD grade stratified by updated 2016 echocardiographic algorithm (DD2016) on post-discharge outcomes patients admitted for acute HF and compare with previous 2009 (DD2009).The study included 481 hospitalized decompensated HF. Comprehensive echocardiography evaluation were performed just before hospital discharge. The primary endpoint was a composite...

10.1093/ehjci/jez082 article EN European Heart Journal - Cardiovascular Imaging 2019-04-09

Left ventricular ejection fraction (LVEF) can dramatically change when the patient has acute decompensated heart failure (ADHF). We investigated impact of LVEF and subsequent changes on prognosis in patients with ADHF through a prospective study.

10.1253/circj.cj-18-0881 article EN Circulation Journal 2019-01-22

Although experimental animal studies report many pleiotropic effects of dipeptidyl peptidase-4 inhibitors (DPP-4i), their prognostic value has not been demonstrated in clinical trials.Methods and Results:Among 838 prospectively enrolled heart failure (HF) patients hospitalized for acute decompensated HF, 79 treated with DPP-4i were compared propensity score-matched non-DPP-4i diabetes mellitus (DM) patients. The primary endpoint was all-cause mortality; the secondary a composite...

10.1253/circj.cj-17-0240 article EN Circulation Journal 2017-01-01

Abstract A 79-year-old woman was brought to the emergency room for chest pain. Acute coronary syndrome suspected and angiography revealed an aneurysm-like contrast accumulation in sinus of Valsalva. Computed tomography aneurysm left Valsalva compressing artery, which required surgical treatment.

10.1093/ehjcr/ytab496 article EN cc-by-nc European Heart Journal - Case Reports 2021-12-01
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