A5031114756- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Parasitic Infections and Diagnostics
- Parasitic infections in humans and animals
- Helminth infection and control
- Parasitic Diseases Research and Treatment
- Dermatological diseases and infestations
- Zoonotic diseases and public health
- Insects and Parasite Interactions
- Rabies epidemiology and control
- Herpesvirus Infections and Treatments
- Insect Utilization and Effects
- Child Nutrition and Water Access
- Toxoplasma gondii Research Studies
AgriBio
2024
The University of Melbourne
2020-2023
La Trobe University
2020
The canine hookworms Ancylostoma braziliense, ceylanicum, caninum and Uncinaria stenocephala are not only capable of producing morbidity mortality in dogs but also neglected tropical zoonoses. Each hookworm species differs considerably its geographical distribution, life cycle, biology, pathogenic impacts on both human hosts, zoonotic potential, response to treatment with anthelminthics. Here we describe the development validation two Taq-Man based multiplex PCR assays detecting...
Background Monitoring the success of soil-transmitted helminth (STH) control programs relies on accurate diagnosis and quantitative assessment infection prevalence intensity. As preventative chemotherapeutic program coverage for STH expands, necessity gaining insights into relative or comparative sensitivities, in terms limits detection (LOD) egg-recovery-rates (ERR) microscopy polymerase chain reaction qPCR-based diagnostic techniques becomes imperative to inform suitability their intended...
Abstract The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic parasitic worm infections suggests a protective role for worms against metabolic disorders, however clinical evidence has been non-existent. This 2-year randomised, double-blinded trial Australia hookworm infection 40 male female adults at risk assessed the safety potential benefits treatment either 20 ( n = 14) or 13) Necator americanus larvae (L3) Placebo (Registration ACTRN12617000818336)....
Ancylostoma ceylanicum hookworms are recognized agents of human infection in the Asia-Pacific region. We investigated prevalence zoonotic hookworm infections dogs Grenada 2021; 40.8% were infected by hookworms, including ceylanicum. Surveillance this parasite and humans is needed tropical/subtropical countries Americas.
Background The Kato-Katz microscopy technique is the global standard for assessment of soil-transmitted helminth (STH) burden. However, major limitations include its poor sensitivity, requirement rapid sample processing, and inability to differentiate hookworm species nor detect Strongyloides spp. infections. We assessed prevalence intensity STH in Solomon Islands by conducting a province-wide survey using quantitative PCR (qPCR) diagnosis, which can provide much better characterisation...
ABSTRACT. There is evolving interest in alternate microscopy techniques and quantitative polymerase chain reaction (qPCR) to evaluate soil-transmitted helminth (STH) burden. Using data from a cross-sectional survey of 540 schoolchildren across six primary schools three municipalities Timor-Leste, we compared the performance using sodium nitrate flotation (SNF) qPCR determining STH prevalence infection intensity. Prevalence by was higher than SNF for Ascaris lumbricoides (17.5% versus 11.2%),...
BackgroundIvermectin mass drug administration (MDA) is effective for controlling onchocerciasis and scabies, with evidence supporting its role in some species of soil-transmitted helminth (STH) infections. In the context RISE, a cluster-randomised trial this study evaluated effectiveness ivermectin MDA reducing STH burden Western Province Solomon Islands.MethodsTwenty villages were randomised 1:1 to receive as one dose (IVM-1) or two doses (IVM-2) scabies. The prevalence intensity was before...
Abstract Soil-transmitted helminths are highly prevalent in the Asia–Pacific region. We report a 96.5% prevalence of zoonotic soil-transmitted dogs Kiribati. advocate for urgent implementation treatment and prevention programs these pathogens, line with Kiribati–World Health Organization Cooperation Strategy 2018–2022.
Introduction. In Cambodia, a limited number of focal surveys targeting dogs in rural communities have reported intestinal helminths potential zoonotic risk as highly endemic. this study, we investigated the prevalence, diversity, distribution, and predictors associated with infecting pet, community, pagoda across urban settings Cambodia through an integrated coproscopic molecular approach. Methods. Faecal samples, demographic, clinical data were collected from 457 Cambodia. Faeces screened...
Over 892 million people in 48 countries are at risk of infection by nematodes that cause lymphatic filariasis. As part the Global Programme to Eliminate Lymphatic Filariasis, mass drug administration is distributed communities until surveillance indicates rates below target prevalence thresholds. In some countries, including American Samoa, filariasis transmission persists despite years and/or has resurged after cessation. Nothing known about population genetics Wuchereria bancrofti worms...
Abstract Ancylostoma ceylanicum is the second most common hookworm infecting humans in Asia-Pacific region. Recent reports suggest presence of parasite Americas. We report A. infections coyotes from Guanacaste Conservation Area, Costa Rica. Our findings call for active surveillance and animals.
In recent years, soil-transmitted helminthiases, including strongyloidiasis have become a prominent public health concern in the southeastern United States of America (USA). While there is ongoing human helminths (STH) surveillance Mississippi and Alabama, very little attention has been paid to potentially zoonotic STH from dogs this region. We microscopically examined faecal samples collected 252 shelter using formalin-ethyl acetate sedimentation method. Extracted DNA were subjected three...
Abstract Canine soil-transmitted helminths (STHs) cause important zoonoses in the tropics, with varying degrees of intensity infection humans and dogs. This study aimed to investigate prevalence associated risk factors for STHs community dogs residing Grenada, West Indies. In May 2021, 232 canine fecal samples were examined zoonotic by microscopy (following flotation), genomic DNA from a subset 211 these subjected multiplex qPCR detection specific identification hookworms, Toxocara spp....
Toxoplasma gondii is a ubiquitous protozoan transmitted by felids and infection, morbidity, mortality occur in numerous marsupial species. This study explores the relationship between cat exposure burrowing bettongs (Bettongia lesueur) Arid Recovery Reserve (ARR), South Australia. We estimated seroprevalence, using modified agglutination test for T. gondii-specific immunoglobulins, cat-free cat-exposed bettong populations. Tissue samples collected opportunistically from carcasses cats within...