A5100624049- Plant Virus Research Studies
- Ecology and Conservation Studies
- Flowering Plant Growth and Cultivation
- Algal biology and biofuel production
- Anaerobic Digestion and Biogas Production
- Biofuel production and bioconversion
- Computational Drug Discovery Methods
- Plant tissue culture and regeneration
- Plant Physiology and Cultivation Studies
- Probiotics and Fermented Foods
- Transgenic Plants and Applications
- Plant and animal studies
- Powdery Mildew Fungal Diseases
- Proteins in Food Systems
- SARS-CoV-2 and COVID-19 Research
- Porphyrin Metabolism and Disorders
- Plant Pathogens and Fungal Diseases
- Botanical Research and Applications
- Fungal Plant Pathogen Control
- Methane Hydrates and Related Phenomena
- Catalysis for Biomass Conversion
- Plant Disease Resistance and Genetics
- Genomics and Phylogenetic Studies
- Burkholderia infections and melioidosis
- GABA and Rice Research
International Vaccine Institute
2024
LG (South Korea)
2022
Ewha Womans University
1997-2021
Sunchon National University
2016-2018
Kyungpook National University
2010-2014
Seoul National University Bundang Hospital
2013
Emory University
2011
Korea Institute of Energy Research
1996-2010
Korea Research Institute of Chemical Technology
2002
There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required. Coronaviruses (CoVs) rising targets of some flavonoids. The antiviral activity flavonoids against CoVs is presumed directly inhibiting 3C-like protease (3CLpro). Here, we applied a flavonoid library to systematically probe inhibitory compounds SARS-CoV 3CLpro. Herbacetin, rhoifolin pectolinarin found efficiently...
Middle East respiratory syndrome-coronavirus (MERS-CoV) is a zoonotic virus transmitted between animals and human beings. It causes MERS with high mortality rate. However, no vaccine or specific treatment currently available. Since antiviral activity of some flavonoids known, we applied flavonoid library to probe inhibitory compounds against MERS-CoV 3C-like protease (3CLpro). Herbacetin, isobavachalcone, quercetin 3-β-d-glucoside helichrysetin were found block the enzymatic 3CLpro. The...
Objectives This study aims to explore English learners’ investment constructions considering the educational and social contexts of Jeju. In particular, this examines how learners are positioned in various learning Jeju their investments can change depending on positions. Methods Data from three participants’ interviews journal writings were analyzed examine process using poststructuralist concept positions investment. Results shows that marginalized may constrain English. education has...
A non-motile and yellow-pigmented bacterium, designated strain WW3T, was isolated from freshwater of Woopo wetland, Republic Korea. Cells were Gram-reaction-negative, aerobic, catalase-positive oxidase-negative. maximum-likelihood phylogenetic tree based on 16S rRNA gene sequences showed that WW3T forms an independent lineage within the genus Altererythrobacter . Strain related distantly to dongtanensisJM27T troitsensisKMM 6042T (97.1% sequence similarity). DNA–DNA relatedness between...
African swine fever (ASF) caused by the ASF virus (ASFV) is most hazardous disease. Since a huge number of pigs have been slaughtered to avoid pandemic spread, intense studies on disease should be followed quickly. Recent reported that flavonoids various antiviral activity including ASFV. In this report, ASFV protease was selected as an target protein cope with ASF. With FRET (Fluorescence resonance energy transfer) method, assayed flavonoid library which composed sixty-five derivatives...
Abstract Small molecules, namely coactivator binding inhibitors (CBIs), that block estrogen signaling by directly inhibiting the interaction of receptor (ER) with proteins act in a fundamentally different way to traditional antagonists, which displace endogenous ligand estradiol. To complement our prior efforts at CBI discovery de novo design, we used high‐throughput screening (HTS) identify CBIs novel structure and subsequently investigated two HTS hits analogue synthesis, finding many...
Glutamic acid is known to be effective for keratinocyte proliferation, but its dermatological application limited due poor solubility in water and various solvents.Here, the efficacy of arginine glutamate ion pair (named as RE:pair) recovering damaged skin improving elasticity was investigated through analysis proliferation collagen synthesis.Following structural RE:pair using spectroscopic methods, a scratch assay, Pro-Collagen I ELISA, tissue changes wound-induced artificial skin, wound...
Abstract Nitric oxide (NO) is a pleiotropic regulator, critical to numerous biological processes, including vasodilatation and macrophage‐mediated immunity. Macrophages express inducible NO synthase (iNOS) produce after lipopolysaccharide (LPS) stimulation. Gallotannins are water‐soluble polyphenols with wide‐ranging activities. Various chemical structures of gallotannins occurring in medicinal food plants that used worldwide showed several remarkable pharmacological In the present study, we...
Lonicera insularis Nakai (Caprifoliaceae) is Korean endemic plant that lives along the shore of Ulleungdo and Dokdo.The aim this study to construct a phylogenetic relationship within six species (L.maackii, L.chrysantha, L.subsessilis, L. harai, morrowii) genus Wigela subsessilis as outgroup intraspecific variation using chloroplast DNA five regions sequences.Sequence analysis revealed both morrowii showed complete homologies in intergenic trnL-trnF, trnS-trnG, psbM-trnD matK coding...
Abstract The crystal structure of HldC from B. pseudomallei ( Bp HldC), the fourth enzyme heptose biosynthesis pathway, has been determined. converts ATP and d ‐ glycero ‐β‐ manno ‐heptose‐1‐phosphate into ADP‐ ‐β ‐d ‐heptose pyrophosphate. belongs to nucleotidyltransferase α/β phosphodiesterase superfamily sharing a common Rossmann‐like fold with conserved T/HXGH sequence motif. invariant catalytic key residues indicate that core mechanism may be similar other closest homologues....
Photoluminescence spectroscopy was used to probe the formation of colloidal TiO 2 sols from a titanium peroxide solution, which were prepared by reaction H O and hydrate gel that precipitated acidic TiOCl solution neutralized NH 4 OH, during aging at 100°C for 0–64 h. Emission spectra revealed broad band luminescence is interpreted as superposition multiple photoluminescence process involving precursors. The maximum peak position shifted shorter wavelength generation dominant emission time...
A non-motile, orange-coloured and rod-shaped bacterial strain, designated strain ZOW29T, was isolated from a seaweed sample collected the South Sea, Republic of Korea. Cells were Gram-stain-negative, aerobic non-motile. The isolate required sea salts for growth. Carotenoid pigment produced. phylogenetic tree based on 16S rRNA gene sequences showed that ZOW29T forms an evolutionary lineage within radiation enclosing members genus Dokdonia with diaphoros MSKK-32T, eikasta PMA-26Tand...
ABSTRACT AdCLD-CoV19-1, a chimeric adenovirus-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, was previously reported to elicit robust antibody responses in mice and non-human primates after single dose. In this study, we conducted systems serology analysis investigate changes humoral immune induced by varying doses of the AdCLD-CoV19-1 vaccine phase I clinical trial. Serum samples from participants receiving either low or high dose were analyzed for features...
The nitrogen‐related phosphoenolpyruvate phosphotransferase system (PTS Ntr ) is involved in controlling ammonia assimilation and nitrogen fixation. additional role of PTS as a regulatory link between carbon utilization Escherichia coli assumed to be closely related molecular functions IIA potassium homeostasis. We have determined the crystal structure from Burkholderia pseudomallei ( Bp ), which causative agent melioidosis. dimeric at 3.0 Å revealed that its active sites are mutually...
A freesia (Freesia hybrida Hort.) 'Dancing Flame' was developed for the cut flower in National Institute of Horticultural Herbal Science 2007. This hybrid selected from a crossing between seedling 'Vulcano' and 'Sailor', which is scarlet double flowering purple single flowering, respectively, 'Figaro' bright red color semi-double 2000. Morphological characteristics were investigated 3 years 2005 to 2007, then it named Flame'. had (RHS R44B) with yellow center Y9A). The growth plant vigorous...