A5046731470- Algal biology and biofuel production
- Advanced biosensing and bioanalysis techniques
- Photosynthetic Processes and Mechanisms
- Gold and Silver Nanoparticles Synthesis and Applications
- Microbial Metabolic Engineering and Bioproduction
- Biosensors and Analytical Detection
- Advanced Biosensing Techniques and Applications
- Biofuel production and bioconversion
- Biodiesel Production and Applications
- Polydiacetylene-based materials and applications
- Aquatic Ecosystems and Phytoplankton Dynamics
- Plasmonic and Surface Plasmon Research
- Antimicrobial Peptides and Activities
- Antioxidant Activity and Oxidative Stress
- Enzyme Catalysis and Immobilization
- Biocrusts and Microbial Ecology
- Plant tissue culture and regeneration
- Monoclonal and Polyclonal Antibodies Research
- Extracellular vesicles in disease
- Microbial Community Ecology and Physiology
- Microbial Fuel Cells and Bioremediation
- Wastewater Treatment and Nitrogen Removal
- Ocular Surface and Contact Lens
- biodegradable polymer synthesis and properties
- Marine and coastal ecosystems
Korea University
2016-2025
Seoul Institute
2015-2020
Government of the Republic of Korea
2017-2018
KG Chemical (South Korea)
2015
Myongji University
2012
Sungkyunkwan University
2004-2010
Korea Advanced Institute of Science and Technology
1992-2007
Sungae Hospital
2002
Korea Institute of Science and Technology
1999-2001
Massachusetts Institute of Technology
1997
Abstract Microalgae are versatile organisms capable of converting CO 2 , H O and sunlight into fuel chemicals for domestic industrial consumption. Thus, genetic modifications microalgae enhancing photosynthetic productivity biomass bio-products generation crucial both academic applications. However, targeted mutagenesis in with CRISPR-Cas9 is limited. Here we report, a one-step transformation Chlamydomonas reinhardtii by the DNA-free method rather than plasmids that encode Cas9 guide RNAs....
Abstract MicroRNAs in exosomes (exosomal miRNAs) have attracted increased attention as cancer biomarkers for early diagnosis and prognosis owing to their stability body fluids. Since strong association exists between exosomal miRNA expression levels breast cancer, the development of effective methods that can monitor both over broad concentration ranges ultralow amounts is critical. Here, a surface‐enhanced Raman scattering (SERS)‐based sensing platform developed quantitative determination...
When grown in the absence of light, Arabidopsis thaliana deetiolated (det) mutants develop many characteristics light-grown plants, including development leaves and chloroplasts, inhibition hypocotyl growth elongation, elevated expression levels light-regulated genes. We show here that dark-grown wild-type seedlings exhibit similar phenotypic traits if any one a variety cytokinins are present medium. further striking phenotype det is unlikely to be caused by different these mutants. The...
Lutein and zeaxanthin are dietary carotenoids reported to be protective against age-related macular degeneration. Recently, the green alga Chlamydomonas reinhardtii has received attention as a photosynthetic cell factory, but potential of this for carotenoid production not yet been evaluated. In study, we selected C. CC-4349 strain best candidate among seven laboratory strains tested production. A knock-out mutant epoxidase gene induced by preassembled DNA-free CRISPR-Cas9 ribonucleoproteins...
Metabolic engineering of cyanobacteria has enabled photosynthetic conversion CO2 to value-added chemicals as bio-solar cell factories. However, the production levels isoprenoids in engineered were quite low, compared other microbial hosts. Therefore, modular optimization multiple gene expressions for metabolic is required farnesyl diphosphate-derived from CO2.Here, we Synechococcus elongatus PCC 7942 with pathways consisting methylerythritol phosphate pathway enzymes and amorphadiene...