A5100661586- Genetic and phenotypic traits in livestock
- Photosynthetic Processes and Mechanisms
- Algal biology and biofuel production
- Microbial Metabolic Engineering and Bioproduction
- Meat and Animal Product Quality
- Agriculture, Soil, Plant Science
- Ruminant Nutrition and Digestive Physiology
- Genetic Mapping and Diversity in Plants and Animals
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Nutrition, Health and Food Behavior
- Reproductive Physiology in Livestock
- Cancer-related molecular mechanisms research
- Microbial Fuel Cells and Bioremediation
- Food Quality and Safety Studies
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Microbial Community Ecology and Physiology
- Gut microbiota and health
- Advanced Photocatalysis Techniques
- Effects of Environmental Stressors on Livestock
- TiO2 Photocatalysis and Solar Cells
- Mycotoxins in Agriculture and Food
- Metabolomics and Mass Spectrometry Studies
Sungkyunkwan University
2012-2025
Rural Development Administration
2011-2024
National Institute of Animal Science
2015-2024
Korea Food Research Institute
2024
Ewha Womans University
2011-2024
Pusan National University
2006-2024
Seoul National University
2014-2023
National Coalition for Cancer Survivorship
2023
National Cancer Center
2023
Sejong University
2018-2023
The history of African indigenous cattle and their adaptation to environmental human selection pressure is at the root remarkable diversity. Characterization this diversity an essential step towards understanding genomic basis productivity survival under farming systems. We analyze patterns genetic variation by sequencing 48 genomes from five populations comparing them 53 commercial taurine breeds. find highest among zebu sanga cattle. Our search for regions reveals signatures adaptive...
Metabolic engineering of cyanobacteria has enabled photosynthetic conversion CO2 to value-added chemicals as bio-solar cell factories. However, the production levels isoprenoids in engineered were quite low, compared other microbial hosts. Therefore, modular optimization multiple gene expressions for metabolic is required farnesyl diphosphate-derived from CO2.Here, we Synechococcus elongatus PCC 7942 with pathways consisting methylerythritol phosphate pathway enzymes and amorphadiene...
Background: Deoxynivalenol (DON) and zearalenone (ZEN) are common food contaminants produced by Fusarium sp. Mycotoxins a potential health hazard because of their toxicological effects on both humans farmed animals. Methods: We analyzed three groups pigs: control group (fed standard diet), the DON ZEN groups, fed diet containing 8 mg/kg 0.8 respectively, for four weeks. Results: exposure decreased body weight (BW), average daily feed intake (ADFI), conversion rate (FCR), serum levels...
Delayed post-polypectomy hemorrhage is a rare but serious complication. The aim of this study was to identify risk factors for the development delayed hemorrhage.This retrospective case-control patients who developed hematochezia after receiving colonoscopic polypectomy. control underwent uneventful polypectomy and were selected at 4:1 ratio.Of 7447 lesions examined from 3253 received polypectomy, 53 (0.7%) 42 (1.3%) hemorrhage, 168 as controls. According multivariate logistic regression...
To compare the Helicobacter pylori (H. pylori) eradication rate of clarithromycin-based triple therapy, metronidazole-based sequential therapy and concomitant therapy.A total 680 patients infected with H. were divided into 4 groups each group was treated a different therapy. Clarithromycin-based applied to first [rabeprazole, amoxicillin clarithromycin (PAC) group: proton pump inhibitor (PPI), amoxicillin, clarithromycin], whereas second metronidazole (PAM) PPI, metronidazole]. The third...
Recent studies in population of European ancestry have shown that 30%∼50% heritability for human complex traits such as height and body mass index, common diseases schizophrenia rheumatoid arthritis, can be captured by SNPs genetic variation attributed to chromosomes are proportion their length. Using genome-wide estimation partitioning approaches, we analysed 49 quantitative traits, many which relevant diseases, 7,170 unrelated Korean individuals genotyped on 326,262 SNPs. For 43 the...
Direct conversion of carbon dioxide (CO2) to value-added chemicals by engineering cyanobacteria has received attention as a sustainable strategy in food and chemical industries. Herein, Synechococcus elongatus PCC 7942, model cyanobacterium, was engineered produce α-farnesene from CO2. As result the lack farnesene synthase (FS) activity wild-type we metabolically S. 7942 express heterologous FS either Norway spruce or apple fruit, resulting detectable peaks α-farnesene. To enhance...
Copy number variation (CNV), a source of genetic diversity in mammals, has been shown to underlie biological functions related production traits. Notwithstanding, there have few studies conducted on CNVs using next generation sequencing at the population level. Illumina NGS data was obtained for ten Holsteins, dairy cattle, and 22 Hanwoo, beef cattle. The sequence each 32 animals varied from 13.58-fold almost 20-fold coverage. We detected total 6,811 deleted across analyzed individuals...
Abstract Many recent RNA-seq studies were focused mainly on detecting the differentially expressed genes (DEGs) between two or more conditions. In contrast, only a few attempts have been made to detect associated with quantitative traits, such as obesity index and milk yield, experiment large number of biological replicates. This study illustrates linear model application trait (TAGs) detection in real datasets: 89 replicated human related data 21 Holsteins’ production data. Based these...
The purpose of this study was to identify potent lactic acid bacteria that could have a great impact on triticale silage fermentation at different moisture levels and determine their anti-bacterial activity high probiotic potential. For purpose, Pediococcus pentosaceus (TC48) Lactobacillus brevis (TC50) were isolated from fermented silage. ability these isolates in powder studied by an ensiling method. TC48 had higher ferment increasing the content than TC50. Extracellular supernatant (ECS)...
Efficient and versatile DNA assembly frameworks have had an impact on promoting synthetic biology to build complex biological systems. To accelerate system development, laboratory automation (or biofoundry) provides opportunity construct organisms assemblies via computer-aided design. However, a modular cloning (MoClo) for multiple limits the biofoundry workflow in terms of simplicity feasibility by preparing number materials such as destination vectors prior process. Herein, we propose...
Chiral metal oxide nanostructures have received tremendous attention in nanotechnological applications owing to their intriguing chiroptical and magnetic properties. Current synthetic methods mostly rely on the use of amino acids or peptides as chiral inducers. Here, we report a general approach fabricate with tunable magneto-chiral effects, using block copolymer (BCP) inverse micelle R/S-mandelic acid (MA). Diverse are prepared by selective incorporation precursors within micellar cores...
Microbial supply of plant extracts is a promising biomanufacturing strategy that requires engineering metabolic pathways and enzymes. This study presents the Corynebacterium glutamicum for heterologous production diterpenes miltiradiene ferruginol. Through targeted pathway modifications, including inactivation pyruvate carboxylase phytoene synthase, HL01 strain was optimized to enhance geranylgeranyl pyrophosphate (GGPP) pools. Overexpression key MEP enzymes (Dxs Idi) implementation three...
Hyaluronic acid (HA) is widely used in pharmaceuticals, medicine, and cosmetics. Sustainable production has shifted to microbial fermentation using engineered GRAS strains. Diverse carbon sources CO2 conversion via microorganisms enhance HA production. Herein we applied advances CRISPR technologies tools optimize metabolic pathway by redirecting portioning cyanobacterium Synechoccous elongatus PCC 7942, demonstrating enhanced S. 7942 lacking hyaluronan synthase (HAS) required engineering for...
Since 2007, 55 adenovirus strains have been isolated from commercial chicken flocks in Korea and identified the pathogenicity of these isolates was confirmed specific-pathogen-free chickens different age. Based on sequencing analysis hexon gene, FAdV were genetically related to IBH-2A strain FAdV3 (4 isolates, 99.2% 100%), KR5 FAdV4 (22 97.9% 99.2%), 764 FAdV9 (11 99.1% 99.3%), 1047 FAdV11 (18 >99%). Experimental infections with four serotypes resulted high mortality 18-day-old embryos...
The volatile compositions in dried white ginseng according to species (Panax ginseng, Panax notoginseng, and quinquefolius) were analyzed compared by applying multivariate statistical techniques gas chromatography-mass spectrometry data sets. Main compounds of the present study sesquiterpenes, such as bicyclogermacrene, (E)-β-farnesene, β-panasinsene, calarene, α-humulene, β-elemene, etc. In particular, α-selinene, α-terpinolene, β-bisabolene, β-phellandrene, β-sesquiphellandrene,...
A common countermeasure to detect threatening drones is the electro-optical infrared (EO/IR) system. However, its performance drastically reduced in conditions of complex background, saturation and light reflection. 3D laser sensor LiDAR used overcome problems 2D sensors like EO/IR, but it not enough small at a very long distance because low energy resolution. To solve this problem, LADAR under development. In work, we study detection methodology adequate which can up 2 km. First, data...
Holstein is known to provide higher milk yields than most other cattle breeds, and the dominant position of today result various selection pressures. have undergone intensive for production in recent decades, which has left genome-wide footprints domestication. To further characterize bovine genome, we performed whole-genome resequencing analysis 10 11 Hanwoo identify regions containing genes as outliers Holstein, including CSN1S1, CSN2, CSN3, KIT whose products are likely involved yield...
A facile strategy is successfully developed for the centimeter-scale preparation of hierarchically porous aminosilica monolith as a CO2 adsorbent just by simple processes solvent-evaporation-induced coating, self-assembly, and concentration tetraethyl orthosilicate sol on surface polymer foam template without any adhesive composite material or hydrothermal treatment. (3-Aminopropyl) trimethoxysilane immobilized silica via gas-phase procedure. The frameworks mimic those at macroscale, are...
Abstract Highly dispersed, core–shell Ni@Al 2 O 3 on activated carbon (AC) catalysts were prepared to develop an effective, external‐hydrogen‐free fractionation process for various types of lignocellulosic biomass. In a mixture formic acid, ethanol, and water at 190 °C, the conversion oak wood produced 23.4 C% lignin‐derived phenolic monomers (LDPMs) highly delignified pulp‐rich solid. At early stage, acid acted as cocatalyst enhance delignification by solvolysis, later it hydrogen source...