- Meat and Animal Product Quality
- Mycotoxins in Agriculture and Food
- Adipose Tissue and Metabolism
- Genetic and phenotypic traits in livestock
- Animal Nutrition and Physiology
- Insect Utilization and Effects
- Ruminant Nutrition and Digestive Physiology
- Cancer-related molecular mechanisms research
- Food Quality and Safety Studies
- Gut microbiota and health
- Urinary Bladder and Prostate Research
- Effects of Environmental Stressors on Livestock
- Animal and Plant Science Education
- Lipid metabolism and biosynthesis
- Veterinary medicine and infectious diseases
- Biochemical effects in animals
- Agriculture, Soil, Plant Science
- Sexual function and dysfunction studies
- Pelvic floor disorders treatments
- Muscle Physiology and Disorders
- Genetic factors in colorectal cancer
- Peroxisome Proliferator-Activated Receptors
- Genetic Mapping and Diversity in Plants and Animals
- Pesticide Residue Analysis and Safety
- Listeria monocytogenes in Food Safety
National Institute of Animal Science
2015-2025
Rural Development Administration
2013-2022
Seoul National University
2001-2022
Chungnam National University Hospital
2022
Chungnam National University
2017-2021
Hallym University
2008-2020
Korea Environment Institute
2020
Korea Polar Research Institute
2016-2018
Korea Institute of Ocean Science and Technology
2016-2018
Chungbuk National University
2017
Intramuscular fat (IMF) in cattle is an important component of traits that influence meat quality. We measured carcass characteristics and gene expression Korean steers to clarify the molecular mechanism(s) underlying IMF deposition LM tissue by determining correlation between content abundance developing models predict using abundance. The determined a balance removal LM. mRNA lipid metabolic genes including lipogenesis [acetyl CoA carboxylase (ACC), fatty acid synthase (FASN)], uptake...
Adipocytes mainly function as energy storage and endocrine cells. Adipose tissues showed the biological genetic difference based on their depots. The of adipocytes between depots might be influenced by inherent programing for adipogenesis. We used RNA-seq technique to investigate transcriptomes in 3 adipose omental (O), subcutaneous (S) intramuscular (I) fats cattle. Sequence reads were obtained from Illumina HiSeq2000 mapped bovine genome using Tophat2. Differentially expressed genes (DEG)...
Overweight and obesity induce serious health problems that exert negative effects on dog's welfare. Body condition score (BCS) is a common method to evaluate the body fat mass in animals. By palpating observing fats under skin it possible predict animal's accumulation condition. BCS also useful tool estimate composition dogs. However, can be subjective when was performed by non-professionals like pet's owners. To develop avoid misevaluation of twenty-four Beagles were enrolled evaluation. In...
We investigated the relationship between injury of spino-thalamo-cortical pathway (STP) and central post-stroke pain (CPSP) in patients with intracerebral hemorrhage, using diffusion tensor tractography (DTT).30 consecutive chronic patients, whom integrity STP medial lemnisco-thalamo-cortical (MLP) were spared both hemispheres, recruited. classified into two groups according to presence CPSP. DTTs obtained FMRIB Software Library. Fractional anisotropy (FA), mean diffusivity (MD), tract...
Abstract Many recent RNA-seq studies were focused mainly on detecting the differentially expressed genes (DEGs) between two or more conditions. In contrast, only a few attempts have been made to detect associated with quantitative traits, such as obesity index and milk yield, experiment large number of biological replicates. This study illustrates linear model application trait (TAGs) detection in real datasets: 89 replicated human related data 21 Holsteins’ production data. Based these...
The present study was conducted to evaluate the effects of black soldier fly larvae oil (BSFLO) from (BSFL) as a partial or total replacement soybean (SBO) on growth performance, fatty acid (FA) profile, and meat quality broiler chickens 1 5 wk age. A 210 male (Ross 308) at one-day age were randomly allotted 3 dietary treatments (10 replicates 7 birds/group): basal control diet (CON), in which SBO replaced by 50% (50 BSFLO) 100% (100 BSFLO. physical measurements chemical traits leg meat,...
Sweet taste is an important factor that regulates calorie intake and contributes to food preferences in humans animals. Therefore, the evaluation of sweet substances essential for various fields such as healthcare, food, pharmaceutical industries. tastants are detected by receptors which class C G-protein-coupled receptors. T1R2 venus flytrap (VFT) receptor known a primary ligand-binding domain tastants. In this study, we developed ultrasensitive artificial bioelectronic tongue based on VFT...
Deoxynivalenol (DON), one of the most common mycotoxins, is frequently found in foods. This study investigated effects orally administered DON on blood biochemical parameters, growth performance, histology, microbial composition, and metabolism rats. After a 1-week adaptation period, 4-week-old rats were 0.9% saline (control), 1 mg/L (T1), 10 (T2), or 50 (T3) by gavage for 49 days. The DON-treated groups had significantly lower body weights than control group (p < 0.05). Blood alkaline...
Various neurological problems of the brain are known to occur in patients with end stage renal disease (ESRD). However, little is about diffusion tensor imaging (DTI) findings ESRD. Using DTI, we attempted investigate DTI ESRD who showed no specific lesions on conventional MRI. We recruited 10 consecutive for whom at least 3 years had passed since start peritoneal dialysis and abnormality neurologic examination. excluded 6 cerebral infarct (4 patients) diabetes mellitus peripheral neuropathy...
Castration increases intramuscular fat (IMF) deposition, improving beef quality in cattle. The present study was performed to determine the global transcriptome changes following castration of bulls and identify genes associated with IMF deposition longissimus dorsi (LM) Korean A customized bovine CombiMatrix oligonucleotide microarray constructed, were determined by hybridization. Transcriptome comparison between steers indicated that 428 8,407 differentially expressed LM greater than two...
Holstein is known to provide higher milk yields than most other cattle breeds, and the dominant position of today result various selection pressures. have undergone intensive for production in recent decades, which has left genome-wide footprints domestication. To further characterize bovine genome, we performed whole-genome resequencing analysis 10 11 Hanwoo identify regions containing genes as outliers Holstein, including CSN1S1, CSN2, CSN3, KIT whose products are likely involved yield...
The prevalence of knee osteoarthritis(OA) in East Asia is as common for men and even higher women than that reported the Caucasian population. Since both population aging economic growth have taken place at a much faster pace Asian countries, such South Korea, one would expect OA to become major public health problem. However, few studies examined influence on quality life (QoL) physical function Asia. aim this cross-sectional study investigate osteoarthritis (OA) (QoL), lower extremity...
Deoxynivalenol (DON) and zearalenone (ZEN) can seriously affect animal health, with potentially severe economic losses. Previous studies have demonstrated that gut microbiota plays a significant role in detoxification. We analyzed the colon contents from three groups of pigs (fed either standard diet, or diet 8 mg/kg DON ZEN). Bacterial 16S rRNA gene amplicons were obtained contents, sequenced using next-generation sequencing on MiSeq platform. Overall, 2,444,635 sequences generated, ≥2000...
The purpose of this study was to investigate the meat metabolite profiles related differences in beef quality attributes (i.e., high-marbled and low-marbled groups) using nuclear magnetic resonance (NMR) spectroscopy. different marbling scores showed significant water content fat content. High-marbled had mainly higher taste compounds than meat. Metabolite analysis between two groups based on partial least square discriminant (PLS-DA). Metabolites identified by PLS-DA, such as...
This study demonstrated the potential effects of rumen microbiota on deposition intramuscular fat, known as marbling. Previous studies fatty acid metabolism in beef cattle have mostly focused biohydrogenating bacteria, whereas those overall microbiota—to understand their roles marbling—have not been systematically performed. The 14 Korean (Hanwoo), which showed similar carcass characteristics and blood metabolites but different marbling scores, were analyzed by 16S rRNA gene sequencing....
The objective of this study was to determine the efficacy mycotoxin sequestering agents for aflatoxin B1 (AFB1), deoxynivalenol (DON), and zearalenone (ZEA) using an in vitro method. twelve toxin tested were seven bentonite products (bentonite A, B, C, D, E, F, G), two aluminosilicate (aluminosilicate A B), a heulandite product, activated charcoal yeast cell wall product. two-step procedure employed mimic conditions temperature, pH, digestive enzymes stomach small intestine pigs. All able...
Objective: The objective of this study was to determine whether dietary black soldier fly (Hermetia illucens, HI) larvae oil (HILO) could serve as an alternative fat source soybean (SBO) in laying hen diets.Methods: We randomly assigned 25-week-old Hy-line Brown hens (n = 144) receive 6 hens/group; eight replicates) a control or experimental diet which SBO replaced with 50% (50HILO) 100% HILO (100HILO).Results: Dietary did not negatively affect body weight productive performance during the...
Because the phosphoenolpyruvate:sugar phosphotransferase system plays multiple regulatory roles in addition to phosphorylation-coupled transport of many sugars bacteria, synthesis its protein components is regulated a highly sophisticated way. Thus far, cAMP receptor (CRP) complex and Mlc are known be major regulators ptsHIcrr ptsG expression response availability carbon sources. In this report, we performed ligand fishing experiments by using promoters as bait find out new factors involved...