Hyun‐Jeong Lee

ORCID: 0000-0002-0983-3696
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About
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Research Areas
  • Influenza Virus Research Studies
  • Virology and Viral Diseases
  • Animal Disease Management and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Microbial infections and disease research
  • Diverse Approaches in Healthcare and Education Studies
  • Cancer and Skin Lesions
  • Adipose Tissue and Metabolism
  • Respiratory viral infections research
  • Vector-Borne Animal Diseases
  • Attention Deficit Hyperactivity Disorder
  • Immune Response and Inflammation
  • Adipokines, Inflammation, and Metabolic Diseases
  • Allergic Rhinitis and Sensitization
  • Dermatology and Skin Diseases
  • Herpesvirus Infections and Treatments
  • Child and Adolescent Psychosocial and Emotional Development
  • Plant Virus Research Studies
  • Congenital Diaphragmatic Hernia Studies
  • Peroxisome Proliferator-Activated Receptors
  • Children's Physical and Motor Development
  • Cellular Mechanics and Interactions
  • Mesenchymal stem cell research
  • Cytomegalovirus and herpesvirus research

Korea University
2024-2025

Korea Advanced Institute of Science and Technology
2024-2025

Korea Institute of Science and Technology
2024-2025

Seoul National University Hospital
2024

Konkuk University
2008-2023

Korea Center for Disease Control and Prevention
2021

Animal and Plant Quarantine Agency
2014-2019

University of Ulsan
2013-2018

Asan Medical Center
2013-2018

Ulsan College
2013-2018

Adipocytes mainly function as energy storage and endocrine cells. Adipose tissues showed the biological genetic difference based on their depots. The of adipocytes between depots might be influenced by inherent programing for adipogenesis. We used RNA-seq technique to investigate transcriptomes in 3 adipose omental (O), subcutaneous (S) intramuscular (I) fats cattle. Sequence reads were obtained from Illumina HiSeq2000 mapped bovine genome using Tophat2. Differentially expressed genes (DEG)...

10.1371/journal.pone.0066267 article EN cc-by PLoS ONE 2013-06-21

Gastric cancers with microsatellite instabilities (MSI) have been reported to be associated favorable prognosis. However, the significance of effect MSI on clinicopathological features, as well its association mucin phenotype, remains unclear.MSI status was assessed in 414 cases gastric cancer using polymerase chain reaction analysis five loci, recommended by National Cancer Institution criteria. The expression mucins (MUC5AC, MUC6, MUC2, and CD10) assessed.Out total cancer, 380 (91.7%), 11...

10.4132/koreanjpathol.2013.47.1.28 article EN The Korean Journal of Pathology 2013-01-01

Avian influenza virus (AIV) circulates among free-ranging, wild birds. We optimized and validated a DNA barcoding technique for AIV isolation host-species identification using fecal samples from was tissue known bird species, the method shown to distinguish 26 species. Subsequently, (n=743) collected waterfowl habitats confirmed findings laboratory tests. All identified AIV-positive hosts (n=35) were members of order Anseriformes. successfully applied surveillance examined epidemiology host...

10.7589/0090-3558-46.2.649 article EN Journal of Wildlife Diseases 2010-04-01

Live bird markets (LBMs) provide an ideal environment for the evolution and interspecies transfer of avian influenza viruses (AIVs). In this study, we analyzed AIVs present in LBMs Korea during winter seasons 2006–08. Sixty-five that belong to four hemagglutination (HA) subtypes AIV (H3, H4, H6, H9) were isolated from 644 pooled tissue or swab samples collected LBMs. Most H9 Galliformes (chickens, silky fowls, pheasants, guinea fowls), other Anseriformes (Pekin ducks mallards). addition,...

10.1637/8785-040109-resnote.1 article EN Avian Diseases 2010-03-01

In January 2014, a viral hemagglutinating agent named UPO216 was isolated from fecal droppings of wild birds at the UPO wetland in South Korea during an avian influenza surveillance program. Electron microscopy identified virus as paramyxovirus (APMV). Pathogenicity tests and molecular pathotyping revealed that avirulent chickens. The assigned to serological group antigenically distinct known serotypes APMV (-1, -2, -3, -4, -6, -7, -8, -9) by hemagglutination inhibition test, despite showing...

10.3389/fmicb.2017.00786 article EN cc-by Frontiers in Microbiology 2017-05-05

Abstract Hypoxia alters the biological functions of skeletal muscle cells to proliferate and differentiate into myotubes. However, cellular responses myoblasts hypoxia differ according levels oxygen types studied. This study examined effect (1% oxygen) on bovine satellite cells. significantly increased proliferation cultured in a growth medium. In addition, PCNA, cyclin D1, cyclin‐dependent kinase‐1 (CDK1) CDK2 expression were increased. facilitated formation myotubes as well stimulation...

10.1016/j.cellbi.2008.03.017 article EN Cell Biology International 2008-04-09

This study examined whether adult bovine muscle satellite cells from 30-month-old Hanwoo cattle are multipo-tential. The were found to have the potential proliferate and differentiate into myoblasts with formation of multinucleated cells. In addition, treatment peroxisome proliferator activating receptor-γ (PPARγ) agonist, rosiglitazone, promoted their trans-differentiation adipocytes significant increases in glycerol accumulation glycerol-3-phosphate dehydrogenase activity. Western blot...

10.1016/s1016-8478(23)17416-4 article EN cc-by-nc-sa Molecules and Cells 2006-10-01

A novel avian paramyxovirus (APMV), Cheonsu1510, was isolated from wild bird feces in South Korea and serologically genetically characterized. In hemagglutination inhibition tests, antiserum against Cheonsu1510 showed low reactivity with other APMVs vice versa. The complete genome of comprised 15,408 nucleotides, contained six open reading frames (3'-N-P-M-F-HN-L-5'), sequence identity to (< 63%) a unique genomic composition. Phylogenetic analysis revealed that related but distinct APMV-1,...

10.1007/s00705-017-3588-6 article EN cc-by Archives of Virology 2017-10-16

The native extracellular matrix is continuously remodeled to form complex interconnected network structures that reversibly regulate stem cell behaviors. Both regulation and understanding of its intricate dynamicity can help modulate numerous However, neither these has yet been achieved due the lack designing modeling such with dynamic controllability. Here we report modularity-based mathematical matrix-emulating ligand inter-cluster connectivity using graph theory. Increasing anisotropy...

10.1038/s41467-024-54557-8 article EN cc-by-nc-nd Nature Communications 2024-12-23

Dysphagia aortica is difficulty in swallowing caused by extrinsic compression of the esophagus due to an ectatic, tortuous, or aneurysmatic atherosclerotic thoracic aorta. This condition very uncommon, and it usually associated with old age, women short stature, hypertension, kyphosis. We report herein a case involving patient dysphagia who had aortic aneurysm.

10.4070/kcj.2009.39.6.258 article EN Korean Circulation Journal 2009-01-01

Avian metapneumovirus (aMPV) causes upper respiratory tract infections in chickens and turkeys. Although the swollen head syndrome (SHS) associated with aMPV has been reported Korea since 1992, this is study isolating from country. We examined 780 oropharyngeal swab or nasal turbinate samples collected 130 chicken flocks to investigate prevalence of isolate 2004-2008. Twelve subtype A 13 B strains were detected clinical by multiplex real-time reverse transcription polymerase chain reaction...

10.4142/jvs.2010.11.1.59 article EN cc-by-nc-sa Journal of Veterinary Science 2010-01-01

Background: Cytomegalovirus (CMV) is one of the most important opportunistic infections in transplant recipients.Currently sero-positivity for CMV IgG before solid organ transplantation laboratory test choice stratifying risk reactivation after transplantation.Theoretically, CMV-specific cell-mediated immune responses should further categorize patients as high or low development.We therefore evaluated usefulness enzyme-linked immunospot (ELISPOT) assay kidney (KT) candidates predicting...

10.3947/ic.2015.47.2.105 article EN cc-by-nc Infection and Chemotherapy 2015-01-01

Objective: The purpose of this study was to investigate the effect methylphenidate (MPH) on growth in Korean children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Methods: medical records 157 subjects (mean age 8.9±2.2 years; 134 boys) ADHD who received treatment MPH for at least 1 year Department Psychiatry Asan Medical Center were retrospectively reviewed. Height weight prospectively obtained gathered. converted age- gender-corrected standard scores (z scores)...

10.1089/cap.2014.0025 article EN Journal of Child and Adolescent Psychopharmacology 2014-10-01
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