A5026078543- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Skin Protection and Aging
- Food Allergy and Anaphylaxis Research
- Nonmelanoma Skin Cancer Studies
- Dermatologic Treatments and Research
- Nail Diseases and Treatments
- Cancer and Skin Lesions
- Nanoparticles: synthesis and applications
- melanin and skin pigmentation
- Contact Dermatitis and Allergies
- Hair Growth and Disorders
- Asthma and respiratory diseases
- Psoriasis: Treatment and Pathogenesis
- Urticaria and Related Conditions
- Soft tissue tumor case studies
- Air Quality and Health Impacts
- Cutaneous Melanoma Detection and Management
- Advancements in Transdermal Drug Delivery
- Acne and Rosacea Treatments and Effects
- Tumors and Oncological Cases
- Cutaneous lymphoproliferative disorders research
- Gold and Silver Nanoparticles Synthesis and Applications
- Healthcare and Venom Research
- Sarcoma Diagnosis and Treatment
Ansan University
2007-2025
Korea University
2016-2025
Hanyang University Seoul Hospital
2009-2022
Dankook University Hospital
2016
Korea University Medical Center
2010-2016
Silla University
2014
Dongguk University
2014
Advanced Dermatology
2008
Konkuk University
2007
Ajou University
2005
A quick and reproducible surface-enhanced Raman scattering (SERS)-based immunoassay technique, using hollow gold nanospheres (HGNs) magnetic beads, has been developed. Here, HGNs show strong enhancement effects from individual particles because hot spots can be localized on the pinholes in particle structure. Thus, used for highly immunoanalysis of cancer markers. Magnetic beads were as supporting substrates formation immunocomplex. This SERS-based technique overcomes problem slow...
Antibody-conjugated gold nanorods (GNRs) have been used for the targeting and imaging of specific cancer markers expressed on surface membrane cells. GNRs with various aspect ratios were fabricated, their surface-enhanced Raman scattering enhancement effects evaluated. To attach selectively onto targets in cells, antibodies immobilized using layer-by-layer deposition method. First, reporter molecules, mercaptopyridine, attached to GNRs, charge was modified poly(sodium 4-styrene-sulfonate)...
Abstract: Silica is a very common material that can be found in both crystalline and amorphous forms. Well-known toxicities of the lung occur after exposure to form silica. However, silica have not been thoroughly studied. The majority vivo studies nanoparticles (NPs) were performed using an inhalation method. Since NPs commonly administered through skin, study dermal toxicity was necessary determine any harmful effects from exposures. present focused on results systemic applying 20 nm...
Abstract: Nanoparticles (NPs) are used commercially in health and fitness fields, but information about the toxicity mechanisms underlying toxic effects of NPs is still very limited. The aim this study to investigate effect(s) 100 nm negatively (ZnO AE100[-] ) or positively AE100[+] charged zinc oxide (ZnO) administered by gavage Sprague Dawley rats, establish a no observed adverse effect level, identify target organ(s). After verification primary particle size, morphology, hydrodynamic zeta...
Please cite this paper as : Up‐regulation of TNF‐alpha secretion by cigarette smoke is mediated Egr‐1 in HaCaT human keratinocytes. Experimental Dermatology 2010; 19 e206–e212. Abstract: Many epidemiologic studies have pointed to a significant association between smoking and inflammatory skin disease such psoriasis. Cigarette induces expression regulators inflammation interleukin (IL)‐1, IL‐6, IL‐8 tumor necrosis factor (TNF)‐α. It was recently demonstrated that early growth response‐1...
Background/purpose The skin plays an important role as a protective barrier against toxic environments and also is route of drug administration. In spite evidence for interest in the penetration nanoparticles, no study has examined effect nanoparticle surface charge on percutaneous absorption. this study, we investigated charges gold nanorods ( GN s) penetration. Methods Using transmission electron microscopy TEM ) image analysis, quantitatively measured ability s to penetrate skin. Results...
Since the treatment guidelines for atopic dermatitis (AD) were released by Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been several advances AD management.We aimed to establish updated evidence- and experience-based AD.We collected a database of references from relevant systematic reviews regarding general management such as bathing skin care, avoidance exacerbating factors, education psychosocial support, use moisturizers topical anti-inflammatory antipruritic...
Although several previous studies have investigated the association between metabolic syndrome (MetS) and androgenetic alopecia (AGA), study results been inconsistent.The aim of this was to investigate relationship presence MetS AGA according gender in a middle-aged Korean population.A population-based cross-sectional conducted on sample from Genome Epidemiology Study. In total, 3408 subjects (1707 men 1701 women) were enrolled January 2008 February 2010. The Norwood classification for...
Background: Since the treatment guidelines for atopic dermatitis (AD) were issued by Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been further advances systemic of AD.Objective: We aimed to establish updated evidence-and experience-based AD.Methods: compiled a database references from relevant systematic reviews and regarding management AD, including antihistamines, antimicrobials, immunomodulators, allergen-specific immunotherapy, phototherapy, adjunctive...
Abstract: Zinc oxide (ZnO) works as a long-lasting, broad-spectrum physical sunblock, and can prevent skin cancer, sunburn, photoaging. Nanosized ZnO particles are used often in sunscreens due to consumer preference over larger sizes, which appear opaque when dermally applied. Although the US Food Drug Administration approved use of nanoparticles (NPs) 1999, there ongoing safety concerns. The aim this study was evaluate subchronic toxicity NPs after dermal application according Organization...
Atopic dermatitis (AD) is a chronic inflammatory skin disease in which T-helper type 2 (Th2)-type immune responses are dominant. Th2 cytokine, interleukin (IL)-33 and thymic stromal lymphopoietin (TSLP) have been suggested to an important role AD. IL-33 highly expressed AD, but its AD has not yet fully understood. To further identify the of we investigated expression TSLP induced by keratinocytes. This study revealed that human Early growth response protein 1 (Egr)-1, transcriptional factor,...
Abstract: This study was undertaken to investigate the potential toxicity and establish no observed adverse effect level (NOAEL) target organ(s) of negatively charged colloidal silica particles different sizes, ie, SiO 2 EN,20(-) (20 nm) or EN,100(-) (100 nm), administered by gavage in Sprague-Dawley rats. After verification physicochemical properties be tested, a preliminary dose range-finding 90-day repeated were conducted according Organisation for Economic Cooperation Development test...