Abstract Background Oral diseases with high prevalence worldwide are recognized as severe health problems. Probiotics used to prevent oral diseases, including dental caries, malodor, periodontitis, and subgingival plaque. In this study, we aimed confirm the antibacterial effect of probiotics on pathogens assess their characterization safety probiotics. Methods The effects Lacticaseibacillus rhamnosus MG4706, paracasei MG4715, Limosilactobacillus reuteri MG4722 growth biofilm formation...

Tae Ji Yun, Jae Jung Lee, YongGyeong Kim, Jeong-Yong Park, Byoung-Kook and Jun Ho Kim. Journal of the Korean Society Food Science Nutrition 2025;54:188-94. https://doi.org/10.3746/jkfn.2025.54.2.188

Non-alcoholic fatty liver disease (NAFLD) is the most common and leading cause of liver-related deaths worldwide. It has been established that microorganisms are involved in interaction between intestinal lumen liver; therefore, studies on probiotics as potential candidates increasing. This study evaluated effects Limosilactobacillus fermentum MG4294 Lactiplantibacillus plantarum MG5289 NAFLD. The reduced lipid accumulation FFA-induced HepG2 by suppressing adipogenic proteins through...

Ultraviolet (UV) B exposure induces wrinkle formation, collagen fiber breakdown, and transepidermal water loss (TEWL). UVB irradiation the expression of mitogen-activated protein kinase (MAPK), activator 1 (AP-1), nuclear factor kappa (NF-κB), which affect matrix metalloproteinases (MMP). We confirmed effects Latilactobacillus sakei wikim0066 (wikim0066) on UVB-irradiated Hs68 cells HR-1 hairless mice cells. restored production type I procollagen by regulating MMP-1 -3, MAPK, AP-1, NF-κB in...

Lactic acid bacteria have become popular because of their γ-aminobutyric (GABA)-producing ability. In the present study, we selected four Levilactobacillus brevis strains (MG5552, MG5405, MG5261, and MG5522) with GABA-producing ability from 33 isolated various fermented foods in South Korea. We evaluated using thin-layer chromatography determined GABA levels produced by each strain an amino analyzer. Moreover, investigated anti-inflammatory activity strains, results revealed that cell-free...

Avian metapneumovirus (aMPV) causes upper respiratory tract infections in chickens and turkeys. Although the swollen head syndrome (SHS) associated with aMPV has been reported Korea since 1992, this is study isolating from country. We examined 780 oropharyngeal swab or nasal turbinate samples collected 130 chicken flocks to investigate prevalence of isolate 2004-2008. Twelve subtype A 13 B strains were detected clinical by multiplex real-time reverse transcription polymerase chain reaction...

Skin photoaging, which causes wrinkles, increased epidermal thickness, and rough skin texture, is induced by ultraviolet B (UVB) exposure. These symptoms photoaging have been reported to be involved in the reduction of collagen expression matrix metalloproteinases (MMPs) activator protein-1 (AP-1). This study investigated protective effects Bifidobacterium animalis subsp. lactis MG741 (Bi. MG741) Hs-68 fibroblasts hairless mice (HR-1) following UVB We demonstrated that Bi. reduces wrinkles...

Ultraviolet B (UVB) exposure causes a breakdown of collagen, oxidative stress, and inflammation. UVB activates mitogen-activated protein kinase (MAPK), activator protein-1 (AP-1), matrix metalloproteinases (MMPs). In this study, we evaluated 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) radical scavenging activity the photoprotective effect lactic acid bacteria LAB strains, including Lactobacillus, Bifidobacterium, Streptococcus genera in UVB-exposed skin fibroblasts. Nine...

Background: Photoaging, induced by chronic ultraviolet B (UVB) exposure, results in the degradation of extracellular matrix (ECM) components, leading to skin roughness, wrinkle formation, and reduced elasticity. Recent studies have explored probiotics as potential inhibitors extrinsic aging, primarily through mechanisms that protect barrier reduce collagen breakdown. Methods: This study investigates anti-photoaging effects Limosilactobacillus fermentum MG5368 (L. MG5368) Lactiplantibacillus...

Rubus coreanus fruit (RF) has been used as a traditional medicine formulation to treat various diseases including diarrhea, asthma, and cancer in East Asia (Korea, China, Japan). RF, which is native Korea, larger size than that of exotic species. In this study, we aimed compare the anti-inflammatory activities immature mature RF extracted with different solvents.Mature (MRF IRF) were 30% ethanol, 70% ethanol water at room temperature. The antioxidant activity was determined using...

Purpose: Aster glehnii (AG) and yomena (AY) are medicinal plants that belong to the family Compositea grow widely in Korea.Plants genus have been used treat snakebite wounds or bruises oriental medicine.This study compared effects of anti-oxidants anti-adipocyte differentiation according species (the aerial parts AG AY).Methods: AY were extracted using 70% ethanol (-E) water (-W) at room temperature.The anti-oxidant activities measured by total phenol contents (TPC), flavonoid (TFC), DPPH...

목적 본 연구의 목적은 생도라지에 비해 증숙 공정을 거친 도라지를 여러 농도의 에탄올로 추출하여 생리활성 효과를 비교 및 조사하여 미백 기능성화장품 소재로서의 활용 가능성을 확인하고자 한다. 방법 B16F10 멜라노마 세포에서 도라지 추출물의 세포독성평가를 확인하기 위하여 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2Htetrazolium (MTS) assay를 수행하였다. 또한, 미백효과를 멜라닌 생합성 함량 측정과 western blot을 통한 생성 관련 인자들의 단백질 발현을 측정하였다. ê²°ê³¼ 추출물은 추출물에 의한 독성을 나타내지 않았다. 측정 결과 70% 에탄올 추출물에서 더 효과적으로 합성을 억제하였다. Tyrosinase-related protein-1 (TRP-1), TRP-2, tyrosinase 또한 ê²°ë¡ 이러한 결과는...

Coreopsis lanceolata L. is a perennial plant of the family Asteraceae, and its flower known to contain flavonoids with various bioactivities. We evaluated effect (CLF) extracts on H2O2-induced oxidative stress (OS) in neuronal cells mouse neurons. The flowering part CL was used as CLF1 (70% ethanol extract) CLF2 (water extract), 10 types phenolic compounds were quantified using high-performance liquid chromatography. To evaluate neuroprotective effects CLF, antioxidant activities measured,...

Periodontitis is a chronic inflammatory disease characterized by tooth loss due to inflammation and the of alveolar bone. closely related various systemic diseases emerging as global health problem. In this study, we investigated anti-inflammatory effect lactic acid bacteria (LAB) in vitro on Porphyromonas gingivalis (P. gingivalis) LPS-activated RAW264.7 human gingival fibroblasts-1 (HGF-1) cells anti-osteoclastogenic LAB RANKL-induced cells. All strains (Lacticaseibacillus rhamnosus...

Reactive oxygen species (ROS), associated with oxidative stress, are involved in many biological processes such as apoptosis, necrosis, and autophagy. Oxidative stress might induce neuronal damage via ROS generation, causing neurodegenerative diseases. Erigeron annuus (EA) has antioxidant properties could protect neurons from stress. In this study, we investigated the protective effect of aerial parts (EAA) flowers (EAF) EA on ROS-mediated apoptosis pheochromocytoma 12 cells. We quantified...

Muscular atrophy is a chronic muscle disease characterized by loss of mass and weakness due to excessive protein breakdown relative synthesis. Apoptosis major factor in sarcopenia the final stage that occurs via various mechanisms. In this study, we evaluated protective effects cell-free supernatants (CFSs) from different lactic acid bacteria (LAB) strains dexamethasone (DEX)-treated C2C12 cells, followed probiotic properties. We found Limosilactobacillus fermentum (L. fermentum) MG4263...

Adipocyte-specific transcription factors and antioxidants are considered the best target of obesity. Aruncus dioicus var. kamtschaticus (A. dioicus, Samnamul) is easily available owing to edible inexpensive. However, anti-adipogenic effects underlying mechanism A. extract (ADE) have not yet been reported. In present study, we evaluate pathway in 3T3-L1 adipocytes, antioxidant activities quantified phenolics using high-performance liquid chromatography ADE. The results revealed ADE had...

External stimulation of the skin by ultraviolet B (UVB) radiation induces oxidative stress or inflammation, causing aging and cancer. Glycyrrhiza uralensis (licorice) has been used as a medicinal plant for its antioxidant, anti-inflammatory, antiviral, antimicrobial, anticarcinogenic, hepatoprotective properties. The present study analyzed effects thermal processing on bioactivities licorice. Heat-treated licorice (HL) extracts had better antioxidant anti-inflammatory activities than...

Purpose: Astragalus membranaceus (AM) is an important traditional medicinal herb.Pharmacological research has indicated that AM various physiological activities such as antioxidant, anti-inflammatory, immunoregulatory, anticancer, hypolipidemic, antihyperglycemic, and hepatoprotective activities.The bioactive substances responsible for the in AM, including many antioxidant substances, change during roasting process.This study investigated compared changes constituents of caused by...

Mushrooms have been widely cultivated and consumed as foods herbal medicines owing to their various biological properties. However, few studies evaluated the anti-inflammatory effects of mushrooms. Here, we investigated mushroom extracts (MEs) on lipopolysaccharide (LPS)-induced inflammation in macrophages (RAW264.7 cells). First, extracted MEs with either water or ethanol. Using LPS-treated RAW264.7 cells, measured cell proliferation NO production. Gene expression tumor necrosis factor-α...