- Neurobiology of Language and Bilingualism
- Infant Development and Preterm Care
- Language Development and Disorders
- Reading and Literacy Development
- Infant Nutrition and Health
- Child Nutrition and Feeding Issues
- Neural dynamics and brain function
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Liver Disease and Transplantation
- HIV, Drug Use, Sexual Risk
- Pain Management and Placebo Effect
- COVID-19 and Mental Health
- Stress Responses and Cortisol
- Syphilis Diagnosis and Treatment
- Digital Mental Health Interventions
- Vascular anomalies and interventions
- Neonatal Respiratory Health Research
- Eosinophilic Esophagitis
- Mental Health Research Topics
- Hearing Loss and Rehabilitation
- Cardiovascular Syncope and Autonomic Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Child Abuse and Trauma
- Reproductive tract infections research
Lurie Children's Hospital
2020-2024
Northwestern University
2020-2024
Children's Hospital of Philadelphia
2024
University of Pennsylvania
2024
University of Pittsburgh Medical Center
2019
University of Pittsburgh
2019
McGill University
2015-2016
Centre for Research on Brain Language and Music
2015-2016
Montreal Neurological Institute and Hospital
2015-2016
Of current interest is how variations in early language experience shape patterns of functional connectivity the human brain. In present study, we compared simultaneous (two languages from birth) and sequential (second learned after age 5 years) bilinguals using a seed-based resting-state MRI approach. We focused on inferior frontal gyrus (IFG) as our ROI, recent studies have demonstrated both neurofunctional neurostructural changes related to second acquisition this cortical area. Stronger...
There is considerable variability in an individual's ability to acquire a second language (L2) during adulthood. Using resting-state fMRI data acquired before training English speakers who underwent 12 week intensive French immersion course, we investigated whether individual differences intrinsic functional connectivity relate person's L2. We focused on two key aspects of processing--lexical retrieval spontaneous speech and reading speed--and computed whole-brain from regions interest the...
Abstract Prenatal stress exposure increases vulnerability to virtually all forms of psychopathology. Based on this robust evidence base, we propose a “Mental Health, Earlier” paradigm shift for prenatal research, which moves from the documentation stress‐related outcomes their prevention, with focus infant neurodevelopmental indicators subsequent mental health problems. Achieving requires an expansive team science approach. As exemplar, introduce Promoting Healthy Brain Project (PHBP),...
Adverse childhood experiences (ACEs) profoundly impact neurocognitive development. Specifically, when these events occur during critical periods of brain plasticity, a time significant synaptogenesis, neural pruning, and myelination, typical neurodevelopment can become derailed. promote morphological changes in neuronal microcircuitry which may lead to diminished cognitive flexibility, inattention, increased impulsivity, decreased school readiness, disruptive behaviors. In this regard, the...
Superior mesenteric artery syndrome (SMAS) occurs when the third portion of duodenum is compressed between superior (SMA) and aorta, causing duodenal obstruction. This condition most commonly arises from marked weight loss that reduces size fat pad these vessels, greater acuity angulation. We present an unusual case SMAS occurring in adolescent due to precipitous resulting cannabinoid hyperemesis (CHS).A 17-year-old presented emergently with voluminous bilious emesis. She endorsed a history...
Abstract Background Post‐infectious disorders of gut‐brain interaction (PI‐DGBI) have significant impact on children and adolescents. The effect COVID‐19 PI‐DGBI‐associated symptoms in this population, however, is unknown. Methods We performed electronic medical record searches to identify patients 8–17 years old with a SARS‐CoV2 PCR test at Lurie Children's Hospital between November 2020 March 2021 (cohort 1) April–October 2). Questionnaires were administered assess prior 3 months following...
Preterm infants are at high risk for systemic inflammatory disorders, including sepsis, meningitis, bronchopulmonary dysplasia, and necrotizing enterocolitis (NEC). The developing brain of the premature newborn is especially susceptible to cascade mediators elaborated in these conditions that cross blood-brain barrier. NEC, a severe potentially fatal condition gut occurs newborns, prime example how an reaction, perhaps initially localized, can become generalized cause harm. One such result...
May 7, 2019April 9, 2019Free AccessThe Effect of Completing a Neurology Clerkship on Diagnostic Accuracy Paroxysmal Spells (P3.5-033)Brian Hanrahan, Arun Antony, Peter Woodward Jones, Jonathan Berken, Desiree Markantone, Alexandra Popescu, and Anto BagicAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.P3.5-033 Letters to the Editor
The incidence of syphilis is rising among adolescents necessitating improved provider awareness and screening practices. We present a case an adolescent with acute hepatitis ultimately diagnosed secondary syphilitic hepatitis. Clinical presentation, laboratory abnormalities, histologic features are nonspecific, diagnosis relying on clinical suspicion targeted testing. This highlights the importance for in sexually active adolescents, variety manifestations including those commonly seen by...