Alexandra Popescu

ORCID: 0000-0003-2078-4458
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About
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Research Areas
  • Epilepsy research and treatment
  • Cardiac Arrest and Resuscitation
  • EEG and Brain-Computer Interfaces
  • Psychosomatic Disorders and Their Treatments
  • Mental Health and Psychiatry
  • Intensive Care Unit Cognitive Disorders
  • Peripheral Artery Disease Management
  • Diabetic Foot Ulcer Assessment and Management
  • Gastrointestinal disorders and treatments
  • Traumatic Brain Injury Research
  • Heart Rate Variability and Autonomic Control
  • Vestibular and auditory disorders
  • Mental Health Treatment and Access
  • Cardiac electrophysiology and arrhythmias
  • Vitamin C and Antioxidants Research
  • Psychotherapy Techniques and Applications
  • Systemic Lupus Erythematosus Research
  • Neonatal and fetal brain pathology
  • Functional Brain Connectivity Studies
  • Liver Disease Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cerebrovascular and Carotid Artery Diseases
  • Skin Protection and Aging
  • Obsessive-Compulsive Spectrum Disorders
  • Cardiovascular Syncope and Autonomic Disorders

Victor Babeș University of Medicine and Pharmacy Timișoara
2017-2025

Loyola University Medical Center
2024

Flinders Medical Centre
2021-2022

Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2021

Clinical Emergency Hospital Bucharest
1996-2021

University of Pittsburgh
2010-2019

University of Pittsburgh Medical Center
2010-2016

Institutul National Victor Babes
2010-2012

Columbia University
2010

Stanford University
2010

Objective We tested the hypothesis that there are readily classifiable electroencephalographic (EEG) phenotypes of early postanoxic multifocal myoclonus (PAMM) develop after cardiac arrest. Methods studied a cohort consecutive comatose patients treated arrest from January 2012 to February 2015. For with clinically evident before awakening, 2 expert physicians reviewed and classified all EEG recordings. Major categories included: Pattern 1, suppression‐burst background high‐amplitude...

10.1002/ana.24697 article EN Annals of Neurology 2016-06-28

Neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps most prevalent manifestation of lupus. The pathogenesis NPSLE multifactorial and involves various inflammatory cytokines, autoantibodies, immune complexes resulting in vasculopathic, cytotoxic autoantibody-mediated neuronal injury. management multimodal has not been subjected to rigorous study. Different treatment regimens include nonsteroidal anti-inflammatory drugs, anticoagulation,...

10.2174/157015911796557984 article EN Current Neuropharmacology 2011-08-01

The identification of neoplastic tissue within normal brain during biopsy and tumor resection remains a problem in the operative management gliomas. A variety nanoparticles are phagocytized by macrophages vivo. This feature may allow optical nanoparticles, such as quantum dots, to colocalize with tumors serve an aid surgical or tumors.Male Fisher rats (Charles River Labs, Wilmington, MA) were implanted intracranially C6 gliosarcoma cell lines establish tumors. Two weeks after implantation...

10.1227/01.neu.0000255334.95532.dd article EN Neurosurgery 2007-02-26

Vitamin C is a powerful antioxidant and facilitates neurotransmission. This study explored association between vitamin deficiency cognitive impairment in older hospitalised patients. prospective recruited 160 patients ≥ 75 years admitted under Geriatric Unit Australia. Cognitive assessment was performed by use of the Mini-Mental-State-Examination (MMSE) with MMSE scores <24 were classified as cognitively-impaired. Fasting plasma levels determined using...

10.3390/antiox11030463 article EN cc-by Antioxidants 2022-02-26

Summary: Pentobarbital and propofol are used for the treatment of refractory status epilepticus or elevated intracranial pressure, typically with continuous EEG monitoring. We report a series patients who developed generalized periodic discharges related to anesthetic withdrawal (GRAWs), different from previous seizure activity. At times, this pattern was misinterpreted as recurrent activity, leading reinstitution drug-induced coma, but resolved spontaneously without additional treatment....

10.1097/wnp.0000000000000051 article EN Journal of Clinical Neurophysiology 2014-06-01

High-frequency oscillations (HFOs) have been proposed as a novel marker for epileptogenic tissue, spurring tremendous research interest into the characterization of these transient events. A wealth continuously recorded intracranial electroencephalographic (iEEG) data is currently available from patients undergoing invasive monitoring surgical treatment epilepsy. In contrast to on research-customized recording systems, clinical acquisition systems remain an underutilized resource HFO...

10.3389/fneur.2014.00149 article EN cc-by Frontiers in Neurology 2014-08-06

Frailty is common in older hospitalised patients and may be associated with micronutrient malnutrition. Only limited studies have explored the relationship between frailty vitamin C deficiency. This study investigated prevalence of deficiency its association severity ≥75 years admitted under a geriatric unit. Patients (n = 160) mean age 84.4 ± 6.4 were recruited underwent assessment by use Edmonton Frail Scale (EFS). an EFS score <10 classified as non-frail/vulnerable/mildly frail those...

10.3390/nu13062117 article EN Nutrients 2021-06-20

Clinical or subclinical hypothyroidism dictates the severity of depressive episodes and more frequently overlaps psychotic phenomenology. There are also major resistant to treatment in patients with euthyroidism, which supplementation antidepressant medication thyroid hormones is beneficial.Systematization meta-analyses from perspectives: depression, autoimmune depression pathology, gestational puerperal pathology association hormonal dispositional changes, presentation therapeutic...

10.4183/aeb.2020.256 article EN Acta Endocrinologica (Bucharest) 2020-01-01

An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, without any other embolic risk factors, was performed. All were classified according to Rutherford classification for ischemia. The primary goal of this assess the amputation in these after revascularization procedures. secondary find correlation between (ALI) severity, patient comorbidities, death, association infection. treated by open surgery (18 patients—81.81%) or means endovascular...

10.3390/jcm10215083 article EN Journal of Clinical Medicine 2021-10-29

Brachial artery aneurysm (BAA) is a serious complication in patients with previous arterio-venous fistula (AVF), renal transplantation (RT), and immunosuppressive regimens. Until now, there has been no standard of care for these patients, especially undergoing chronic dialysis treatment. The aim this study was to investigate data from the literature regarding suggest recommendations best approach their treatment.A review performed by searching PubMed database English language. accompanied...

10.3390/healthcare10030470 article EN Healthcare 2022-03-03

UVA affects epidermal cell physiology in a complex manner, but the harmful effects have been studied mainly terms of DNA damage, mutagenesis and carcinogenesis. We investigated on membrane integrity antioxidant defense dysplastic keratinocytes after one two hours irradiation, both immediately exposure, 24 h post-irradiation. To determine oxidative stress membrane, lipid peroxidation was correlated with changes fatty acid levels. Membrane permeability were assessed by propidium iodide...

10.3390/ijms131216718 article EN International Journal of Molecular Sciences 2012-12-06
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