Olivier Xhaët
A5048138777- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Neuroscience of respiration and sleep
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- High Altitude and Hypoxia
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Heart Disease Studies
- Vascular anomalies and interventions
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiovascular and Diving-Related Complications
- Cardiovascular and exercise physiology
- Acute Myocardial Infarction Research
- Transplantation: Methods and Outcomes
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- EEG and Brain-Computer Interfaces
- Pharmaceutical Economics and Policy
- Acute Ischemic Stroke Management
- Electrodeposition and Electroless Coatings
UCLouvain
2012-2025
CHU Dinant Godinne UCL Namur
2011-2023
University of Namur
2022
University of Liverpool
2021-2022
Laboratoire Informatique d'Avignon
2022
Aalborg University
2021-2022
Liverpool Heart and Chest Hospital
2021-2022
Azienda Ospedaliero-Universitaria di Modena
2022
University of Modena and Reggio Emilia
2022
Carol Davila University of Medicine and Pharmacy
2021
The Atrial Fibrillation Ablation Pilot Study is a prospective registry designed to describe the clinical epidemiology of patients undergoing an atrial fibrillation (AFib) ablation, and diagnostic/therapeutic processes applied across Europe. aims 1-year follow-up were analyse how centres assess in routine practice success procedure evaluate rate long-term safety/complications.Seventy-two 10 European countries asked enrol 20 consecutive first AFib ablation procedure. A web-based case report...
Contemporary data regarding atrial fibrillation (AF) management and current use of oral anticoagulants (OACs) for stroke prevention are needed.The EURObservational Research Programme on AF (EORP-AF) Long-Term General Registry analysed consecutive patients presenting to cardiologists in 250 centres from 27 European countries. From 2013 2016, 11 096 were enrolled (40.7% female; mean age 69 ± years). At discharge, OACs used 9379 (84.9%), with non-vitamin K antagonists (NOACs) accounting 40.9%...
Clinical complexity is increasingly prevalent among patients with atrial fibrillation (AF). The 'Atrial Better Care' (ABC) pathway approach has been proposed to streamline a more holistic and integrated AF care; however, there are limited data on its usefulness clinically complex patients. We aim determine the impact of ABC in contemporary cohort patients.From ESC-EHRA EORP-AF General Long-Term Registry, we analysed patients, defined as presence frailty, multimorbidity and/or polypharmacy. A...
Abstract Background Frailty is a medical syndrome characterised by reduced physiological reserve and increased vulnerability to stressors. Data regarding the relationship between frailty atrial fibrillation (AF) are still inconsistent. Objectives We aim perform comprehensive evaluation of in large European cohort AF patients. Methods A 40-item index (FI) was built according accumulation deficits model patients enrolled ESC-EHRA EORP-AF General Long-Term Registry. Association baseline...
Aims In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed. Methods and results We report 1-year follow-up from the EURObservational Research Programme Atrial Fibrillation (EORP-AF) General Long-Term Registry. Outcomes were assessed according to antithrombotic therapy. At follow-up, 9663 (88.0%) had available for...
Background— The remote magnetic navigation system (MNS) has been used with a nonirrigated catheter for atrial fibrillation (AF) ablation. objective of this study was to evaluate the feasibility and efficiency newly available irrigated tip index pulmonary vein isolation (PVI) in patients paroxysmal AF (PAF). Methods Results— Between January 2008 June 2009, 30 consecutive drug-resistant PAF underwent circular mapping catheter-guided PVI MNS (MNS group). outcomes were compared retrospectively...
Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients' phenotypes and analyse differential course.We performed a hierarchical cluster analysis based on Ward's Method Squared Euclidean Distance using 22 binary variables, identifying optimal number clusters. investigated differences management, use healthcare resources outcomes cohort patients from Europe-wide observational...
Sympathetic overactivity is implicated in the increased cardiovascular risk of cigarette smokers. Excitatory nicotinic receptors are present on peripheral chemoreceptor cells. Chemoreceptors located carotid and aortic bodies increase ventilation (Ve), blood pressure (BP), heart rate (HR), sympathetic nerve activity to muscle circulation (MSNA) response hypoxia. We tested hypothesis that nicotine replacement therapy (NRT) increases MSNA sensitivity Sixteen young healthy smokers were included...
Cardiac resynchronization therapy (CRT) decreases muscle sympathetic nerve activity (MSNA) in patients with severe congestive heart failure (CHF) and cardiac asynchrony. Whether this affects equally who clinically respond or not to CRT is unknown. We tested the hypothesis that favorable effects of on MSNA disappear interruption only those CRT. Twenty-three consecutive CHF participated study, among whom 16 presented a symptomatic improvement by one more New York Heart Association (NYHA)...
The occurrence of atrial tachycardias (AT) is a direct function the volume tissue ablated in patients with fibrillation (AF). Thus, incidence AT highest persistent AF undergoing stepwise ablation using strategic combination pulmonary vein isolation, electrogram based and left linear ablation. Using deductive mapping strategy, can be divided into three clinical categories viz. macroreentry, focal newly described localized reentry all which are amenable to catheter success rate 95%....
Abstract Aims Bleeding risk assessment is recommended in guidelines for the management of atrial fibrillation (AF). The HAS-BLED score was proposed prior to non-vitamin K antagonist oral anticoagulants (NOACs) and it has been suggested that ORBIT may be superior predicting bleeds NOAC users. We aimed compare scores contemporary AF patients treated with NOACs. Methods results analysed enrolled ESC-EHRA EORP-AF (EURObservational Research Programme AF) General Long-Term Registry. were computed...
Purpose: We tested the hypothesis that aging decreases contribution of metaboreceptors to sympathetic responses during exercise in hypoxia. Methods: recorded nerve traffic muscle circulation (MSNA), heart rate (HR), blood pressure (BP), minute ventilation (VE), and lactate (BL) 12 older (55 ± 10 yr) younger (22 2 normal subjects three randomized interventions: isocapnic hypoxia (chemoreflex activation), isometric handgrip (HG) normoxia (metaboreflex HG (concomitant metaboreflex chemoreflex...
The 4S-AF classification scheme comprises of four domains: stroke risk (St), symptoms (Sy), severity atrial fibrillation (AF) burden (Sb), and substrate (Su). We sought to examine the implementation in EORP-AF General Long-Term Registry compare outcomes AF patients according 4S-AF-led decision-making process.Atrial from 250 centres across 27 European countries were included. A score was calculated as sum each domain with a maximum 9. Of 6321 patients, 8.4% had low 47.5% EHRA I 40.5% newly...
Muscle metaboreceptors and peripheral chemoreceptors exert differential effects on the cardiorespiratory autonomic responses following hypoxic exercise. Whether these are accompanied by specific changes in sympathetic cardiac baroreflex control is not known. Sympathetic functions were assessed intravenous nitroprusside phenylephrine boluses 15 young male subjects. Recordings performed random order, under locally circulatory arrested conditions, during: (1) rest normoxia (no metaboreflex no...
Heart transplantation initially normalizes sympathetic hyperactivity directed at the muscle circulation. However, activity increases with time after and exact mechanisms responsible for control in heart transplant recipients remain unclear. We examined effects of peripheral chemoreflex deactivation caused by breathing 100% oxygen on nerve (expressed as number burst per minute mean amplitude), rate, blood pressure 13 recipients, patients essential hypertension, 10 controls. disclosed highest...
AimsAblation is an effective treatment of symptomatic and drug refractory atrial fibrillation (AF). Using data from the European AF Ablation Pilot Registry comprising 1410 patients 10 countries, we prospectively investigated regional differences in ablation regarding patient selection, strategy, outcome.