Ömer Erküner
A5041467461- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Health Systems, Economic Evaluations, Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Acute Ischemic Stroke Management
- Frailty in Older Adults
- S100 Proteins and Annexins
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- ECG Monitoring and Analysis
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Occupational and environmental lung diseases
- Neuroscience and Neural Engineering
- Blood Coagulation and Thrombosis Mechanisms
- Pharmaceutical Economics and Policy
Maastricht University Medical Centre
2016-2024
Maastricht University
2016-2023
Liverpool Heart and Chest Hospital
2021-2022
University of Liverpool
2021-2022
Laboratoire Informatique d'Avignon
2022
Aalborg University
2021-2022
Azienda Ospedaliero-Universitaria di Modena
2022
University of Modena and Reggio Emilia
2022
VieCuri Medisch Centrum
2021
Clinical complexity is increasingly prevalent among patients with atrial fibrillation (AF). The 'Atrial Better Care' (ABC) pathway approach has been proposed to streamline a more holistic and integrated AF care; however, there are limited data on its usefulness clinically complex patients. We aim determine the impact of ABC in contemporary cohort patients.From ESC-EHRA EORP-AF General Long-Term Registry, we analysed patients, defined as presence frailty, multimorbidity and/or polypharmacy. A...
Atrial fibrillation (AF) often starts as a paroxysmal self-terminating arrhythmia. Limited information is available on AF patterns and episode duration of AF. In patients, we longitudinally studied the temporal patterns, association with clinical characteristics, prevalence progression.In this interim analysis Reappraisal AF: Interaction Between HyperCoagulability, Electrical Remodelling, Vascular Destabilisation in Progression (RACE V) registry, 202 patients were followed continuous rhythm...
Abstract Atherothrombosis is a leading cause of cardiovascular mortality and long-term morbidity. Platelets coagulation proteases, interacting with circulating cells in different vascular beds, modify several complex pathologies including atherosclerosis. In the second Maastricht Consensus Conference on Thrombosis, this theme was addressed by diverse scientists from bench to bedside. All presentations were discussed audience members results these discussions incorporated final document that...
Progression of atrial fibrillation (AF) from paroxysmal to persistent forms is an active field research. The influence AF progression on health related quality life (HRQoL) currently unknown. We aimed assess the HRQoL, and whether this association mediated through symptoms, treatment, major adverse events.In Euro Heart Survey, 967 patients were included with who filled out EuroQoL-5D at baseline 1 year follow-up. Those progressed (n = 132, 13.6%) developed more problems during follow-up than...
Abstract Aims The recent 4S-AF (scheme proposed by the 2020 ESC AF guidelines to address stroke risk, symptom severity, severity of burden and substrate provide a structured phenotyping patients in clinical practice guide therapy assess prognosis) scheme has been as characterize with atrial fibrillation (AF). We aimed whether predicts progression self-terminating AF. Methods results analysed 341 included well-phenotyped Reappraisal Atrial Fibrillation: Interaction between HyperCoagulability,...
Abstract Aims Bleeding risk assessment is recommended in guidelines for the management of atrial fibrillation (AF). The HAS-BLED score was proposed prior to non-vitamin K antagonist oral anticoagulants (NOACs) and it has been suggested that ORBIT may be superior predicting bleeds NOAC users. We aimed compare scores contemporary AF patients treated with NOACs. Methods results analysed enrolled ESC-EHRA EORP-AF (EURObservational Research Programme AF) General Long-Term Registry. were computed...
The 4S-AF classification scheme comprises of four domains: stroke risk (St), symptoms (Sy), severity atrial fibrillation (AF) burden (Sb), and substrate (Su). We sought to examine the implementation in EORP-AF General Long-Term Registry compare outcomes AF patients according 4S-AF-led decision-making process.Atrial from 250 centres across 27 European countries were included. A score was calculated as sum each domain with a maximum 9. Of 6321 patients, 8.4% had low 47.5% EHRA I 40.5% newly...
Subcutaneous implantable cardioverter-defibrillators (S-ICDs) have become established in preventing sudden cardiac death, with some advantages over transvenous defibrillator systems, including a lower incidence of lead failures. Despite technological advancements, S-ICD carriers may suffer from significant complications, such as premature battery depletion (PBD), that led to an advisory for nearly 40 000 patients. This multicentre study evaluated the PBD large set
Hypertension is a risk factor for both progression of atrial fibrillation (AF) and development AF-related complications, that major adverse cardiac cerebrovascular events (MACCE). It unknown whether left ventricular hypertrophy (LVH) as consequence hypertension also these end points. We aimed to assess this in low-risk AF patients, assessing gender-related differences. included 799 patients from the Euro Heart Survey with nonvalvular baseline echocardiogram. Patients without were included....
Abstract Aims The clinical risk profile of atrial fibrillation (AF) patients is different in men and women. Our aim was to identify sex differences blood biomarkers with paroxysmal AF. Methods results Sex 92 were measured 364 included our discovery cohort, the identification a guide therapy (AF-RISK) study, assessed by multivariable logistic regression enrichment pathway analysis. Findings subsequently confirmed 213 validation Reappraisal Atrial Fibrillation: Interaction between...
Abstract Background Atrial tachyarrhythmias are common in patients with cardiac implantable electronic devices (CIEDs). Restoration of sinus rhythm by external electrical cardioversion (eECV) is frequently used to alleviate symptoms and ensure optimal device function. Objectives To evaluate the safety eECV contemporary CIEDs assess need for immediate interrogation after eECV. Methods We conducted a retrospective observational study 229 (27.9% female, age 69 ± 10 years) CIED (104 pacemakers,...
Abstract Background The current standard of care for acute atrial fibrillation (AF) focuses primarily on immediate restoration sinus rhythm by cardioversion, although AF often terminates spontaneously. Objective To identify determinants early spontaneous conversion (SCV) in patients presenting at the emergency department (ED) because AF. Methods An observational study was performed who visited ED with documented between July 2014 and December 2016. clinical characteristics demographics...
Subcutaneous implantable cardioverter-defibrillators (S-ICDs) offer potentially distinct advantages over transvenous defibrillator systems. Recent randomized trials showed significantly lower lead failure rates than ICD. Still, S-ICDs remain associated with the risk of inappropriate shocks (IAS). While previous studies have reported varying causes IAS, this study explores a rare cause referred to as 'sense-B-noise.' It was recently described in case series, but its incidence has not been...
BackgroundPatients undergoing elective electrical cardioversion (ECV) for atrial fibrillation have a temporarily increased risk of thromboembolism. Current guidelines recommend adequate anticoagulation ≥3 consecutive weeks precardioversion, i.e. INR values 2.0–3.0 in patients with vitamin K antagonists (VKA). We aimed to evaluate the occurrence and impact subtherapeutic INRs precardioversion study factors associated these unwanted fluctuations.MethodsWe recruited 346 ECV Maastricht...
Abstract Background Contemporary data regarding the characteristics, treatment and outcomes of patients with atrial fibrillation (AF) are needed. We aimed to assess these guideline adherence in EURObservational Research Programme on Atrial Fibrillation (EORP-AF) long-term general registry. Methods analysed 967 from EORP-AF registry included Netherlands Belgium 2013 2016. Baseline 1‑year follow-up were gathered. Results At baseline, 887 (92%) received anticoagulant treatment. In 88 (10%)...
stenosis, or intracranial arterial stenosis) risk factors were investigated at the time of index stroke.Results: 1.The number CE and non-CE increased with increasing CHADS2 / CHA2DS2-VASc scores (p trends <0.001).2. The presence was independently associated old age (p¼0.011),high coronary calcium score (p¼0.001), 2 (p<0.001).3. persistent AF (p<0.001),body mass (p¼0.005),left atrial volume (<0.001),and (p¼0.001).4. could be used to identify patients (p<0.001)regardless previous myocardial...