A5083176069- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Cardiovascular Syncope and Autonomic Disorders
- Acute Ischemic Stroke Management
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Mechanical Circulatory Support Devices
- Cardiomyopathy and Myosin Studies
- Central Venous Catheters and Hemodialysis
- Breast Implant and Reconstruction
- Anatomy and Medical Technology
- Reconstructive Facial Surgery Techniques
- Advanced MRI Techniques and Applications
- Muscle activation and electromyography studies
- Meteorological Phenomena and Simulations
- Metabolism and Genetic Disorders
- Gastroesophageal reflux and treatments
- Anesthesia and Sedative Agents
- Cardiovascular Effects of Exercise
- Heart Failure Treatment and Management
University Hospital Cologne
2017-2025
University of Cologne
2015-2025
Centrum für Integrierte Onkologie
2015-2023
Mitral valve transcatheter edge-to-edge repair (M-TEER) has emerged as a viable therapy option in patients with severe mitral regurgitation and high surgical risk. Although atrial fibrillation is common among undergoing M-TEER, the optimal anticoagulatory treatment after intervention unknown. A single-center retrospective observational analysis was conducted using data from M-TEER registry at University Hospital Cologne collected 2019 untill 2021 including between November 2012 April 2019....
Background/Objectives: Pulmonary vein isolation (PVI) is the cornerstone in treatment of atrial fibrillation (AF). Despite initially successful PVI patients experience recurrence AF potentially due to reconnection pulmonary veins (PVs). However, a certain number present with recurrent AF, despite durable PVI. The optimal ablation strategy for these has yet be discerned. aim this study was compare outcomes different strategies persistent Methods: All redo procedures from March 2018–May 2023...
Pulmonary vein isolation (PVI) remains the cornerstone in treatment of atrial fibrillation (AF). PVI using cryoballoon (CB) technology has emerged as a standard procedure many centers. Recently, pulsed field ablation (PFA) been introduced and used to achieve PVI. First data show high acute favorable long-term outcomes. So far, comparing these new "single shot" devices are sparse. We sought compare procedural outcome for first time PFA users versus CB patients undergoing de novo Furthermore,...
Abstract Background The newly introduced nonthermal pulsed field ablation (PFA) is a promising technology to achieve fast pulmonary vein isolation (PVI) with high acute success rates and good safety features. However, previous studies have shown that very power short duration (VHPSD) also highly effective PVI potentially less arrhythmia recurrence compared conventional radiofrequency ablation. Data comparing PFA VHPSD‐PVI lacking. Objective This study procedural outcome data for PFA‐PVI in...
Abstract Background and Aims Patients with left-ventricular-assist-devices (LVAD) are at high risk for ventricular tachycardia (VT), data on VT ablation in LVAD patients is scarce. This multicentre registry assessed the mechanism of VT, procedural parameters, outcome (NCT06063811). Methods Data referred 9 tertiary care centres were collected retrospectively. Parameters included mechanisms, data, recurrence, mortality. Results Overall, 69 (90% male, mean age 60.7±8.4 years) undergoing 72...
Abstract Background Pulmonary vein isolation (PVI) is a first-line treatment option for paroxysmal atrial fibrillation (PAF). Radiofrequency ablation (RFA) or Cryoballoon (CBA) are commonly used modalities. Recent studies demonstrated the superiority and potential benefits of very high-power short-duration (vHPSD) RFA using 70 Watts compared to conventional (<50 Watts). Prospective randomized data comparing vHPSD with frequently CBA in setting PAF lacking. Methods We conducted...
In 180 patients, cerebral blood flow was measured between one and six weeks after acute cerebrovascular ischemia. Patients were grouped according to their clinical deficits at the time of study. Statistical analysis revealed highly significant differences among values groups. The patients followed up for a period 6 years (mean, 34 months) attack, then regrouped. these groups, statistical significances even higher. also changes in neurologic status, again differed significantly results show...
Subcutaneous implantable cardioverter-defibrillators (S-ICDs) have become established in preventing sudden cardiac death, with some advantages over transvenous defibrillator systems, including a lower incidence of lead failures. Despite technological advancements, S-ICD carriers may suffer from significant complications, such as premature battery depletion (PBD), that led to an advisory for nearly 40 000 patients. This multicentre study evaluated the PBD large set
Pulmonary vein isolation (PVI) is achievable and effective using radiofrequency (RF) catheter (CA) or cryoballoon (CB) ablation. The newly introduced high RF-power short-duration ablation (HPSD) technique has shown promising results. Data comparing HPSD- to CB-PVI sparse. We sought investigate success rates procedural differences of HPSD-PVI vs. in patients undergoing for PAF persAF.Consecutive de novo PVI (HPSD CB) were included. A power setting 70W/7 s (70W/5 at posterior wall) a flexible...
The MicraVR™ transcatheter pacing system (TPS) has been implemented into clinical routine for several years. primary recipients are patients in need VVI due to bradycardia the setting of atrial fibrillation (AF). Implantation safety and acute success have proven controlled studies registries. So far only few long-term real-life data on TPS exist. We report indication, procedure outcome from two high-volume implanting German centers.Between 2016 2019, 188 (of 303) were included. During...
This study aimed to determine if changes in myeloperoxidase (MPO) levels correlate with response cardiac resynchronization therapy (CRT) and the potential role of MPO as a predictor CRT.CRT is well-established treatment option chronic heart failure (CHF) 50-80% patients benefiting. Inflammation oxidative stress play key CHF pathophysiology. Previous studies have demonstrated increased patients, but correlation CRT remains incompletely understood.Fifty-three underwent implantation. During...
Current implantable cardioverter-defibrillator (ICD) guidelines do not impose age limitations for ICD implantation (IMPL) and generator exchange (GE); however, patients (pts) should be expected to survive 1 year. With higher age, comorbidity mortality due non-sudden cardiac death increase. Thus, the benefit of therapy in elderly pts remains unclear. Mortality after IMPL or GE ≥ 75 years was assessed.
Abstract We present a case of patient with baroreflex activation therapy (BAT) receiving subcutaneous implantable cardioverter defibrillator (S‐ICD). anticipated two possible hazardous interactions between the devices. Stimulation by BAT could be adjudicated as noise and result in underdetection ventricular arrhythmias or it might misinterpreted lead to inappropriate shocks. Postop ensing occurred, upper limit pulse width was limited because detection S‐ICD, but amplitude patient's...
Cryoballoon (CB) ablation and radiofrequency (RF) are the most common techniques for pulmonary vein isolation (PVI) in patients with symptomatic atrial fibrillation (AF). An increasing number of undergoing PVI obese. To address paucity data on outcomes CB- vs. RF-based relation to body mass index (BMI) AF patients.
Abstract Background Reduced biventricular pacing (BiVP) is a common phenomenon in cardiac resynchronization therapy (CRT) with impact on CRT-response and patients’ prognosis. Data treatment strategies for patients ventricular arrhythmia BiVP reduction sparse. We sought to assess the effects of BiVP. Methods In this retrospective analysis, data CRT reduced ≤ 97% due were analyzed. Catheter ablation or intensified medical was performed optimize Results included 64 consecutive (73 ± 10 years,...
Abstract Background The cryoballoon (CB) has become a standard tool for pulmonary vein isolation (PVI), but the technology is limited in certain ways. A novel RF-balloon (Heliostar™, Biosense Webster, CA, USA) promises advantages of balloon combination with 3D mapping. Methods To assess procedural data and outcome, all patients undergoing PVI were included compared from consecutive CB paroxysmal AF. Results total 254 (63 ± 13 years, 54% male) included: 30 224 PVI. Baseline parameters...
Abstract Background Pulmonary vein isolation (PVI) is recommended in patients with symptomatic atrial fibrillation (AF) and reduced left ventricular ejection fraction (LVEF). Recently the Castle HTx (CHTx) trial showed a significant mortality reduction end stage heart failure undergoing PVI addition to optimized medical therapy (OMT) compared OMT only. Aim Objective of this analysis validate results study real world scenario. Methods All between September 2021 und 2023 referred for at our...
Abstract Background Catheter ablation is an established therapy for ventricular tachycardia (VT) with endocardial voltage map (EVM) being the standard tool to characterize proarrhythmic substrate. However, this method limited in certain ways, especially as intramural or epicardial substrate not detected. In context, multi-detector computed tomography (MDCT) has emerged a promising alternative cardiac MRI preprocedural assessment. Purpose Data regarding MDCT- guided VT scarce, context of late...
Abstract Background Therapy of polymorphic premature ventricular contractions (pPVC) is sometimes challenging despite improved catheter ablation options especially in patients suffering from non-ischemic cardiomyopathy. Previous studies have proven the benefit non-selective ß-blocker such as propranolol stetting electrical storm. Data for use to treat pPVC sparse. Aim We sought analyze potential setting failed or only partially successful ablation. Methods This retrospective analysis...