Cornelia Scheurlen

ORCID: 0000-0001-7054-3535
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Venous Thromboembolism Diagnosis and Management
  • Health Systems, Economic Evaluations, Quality of Life
  • Central Venous Catheters and Hemodialysis
  • ECG Monitoring and Analysis
  • Neurological disorders and treatments
  • Meteorological Phenomena and Simulations
  • Drug-Induced Hepatotoxicity and Protection
  • Genital Health and Disease
  • Insurance, Mortality, Demography, Risk Management
  • Malaria Research and Control
  • Restraint-Related Deaths
  • Cardiomyopathy and Myosin Studies
  • Cardiac Imaging and Diagnostics
  • Hemoglobinopathies and Related Disorders
  • Cardiac Valve Diseases and Treatments
  • Voice and Speech Disorders

University of Cologne
2022-2025

University Hospital Cologne
2021-2025

Centrum für Integrierte Onkologie
2022-2023

Background/Objectives: Pulmonary vein isolation (PVI) is the cornerstone in treatment of atrial fibrillation (AF). Despite initially successful PVI patients experience recurrence AF potentially due to reconnection pulmonary veins (PVs). However, a certain number present with recurrent AF, despite durable PVI. The optimal ablation strategy for these has yet be discerned. aim this study was compare outcomes different strategies persistent Methods: All redo procedures from March 2018–May 2023...

10.3390/jcm14072250 article EN Journal of Clinical Medicine 2025-03-26

Pulmonary vein isolation (PVI) remains the cornerstone in treatment of atrial fibrillation (AF). PVI using cryoballoon (CB) technology has emerged as a standard procedure many centers. Recently, pulsed field ablation (PFA) been introduced and used to achieve PVI. First data show high acute favorable long-term outcomes. So far, comparing these new "single shot" devices are sparse. We sought compare procedural outcome for first time PFA users versus CB patients undergoing de novo Furthermore,...

10.1111/jce.16056 article EN cc-by Journal of Cardiovascular Electrophysiology 2023-09-08

Abstract Background The newly introduced nonthermal pulsed field ablation (PFA) is a promising technology to achieve fast pulmonary vein isolation (PVI) with high acute success rates and good safety features. However, previous studies have shown that very power short duration (VHPSD) also highly effective PVI potentially less arrhythmia recurrence compared conventional radiofrequency ablation. Data comparing PFA VHPSD‐PVI lacking. Objective This study procedural outcome data for PFA‐PVI in...

10.1111/jce.16101 article EN cc-by Journal of Cardiovascular Electrophysiology 2023-10-17

Abstract Background Pulmonary vein isolation (PVI) is a first-line treatment option for paroxysmal atrial fibrillation (PAF). Radiofrequency ablation (RFA) or Cryoballoon (CBA) are commonly used modalities. Recent studies demonstrated the superiority and potential benefits of very high-power short-duration (vHPSD) RFA using 70 Watts compared to conventional (<50 Watts). Prospective randomized data comparing vHPSD with frequently CBA in setting PAF lacking. Methods We conducted...

10.1093/europace/euaf066 article EN cc-by-nc EP Europace 2025-03-31

Pulmonary vein isolation (PVI) is achievable and effective using radiofrequency (RF) catheter (CA) or cryoballoon (CB) ablation. The newly introduced high RF-power short-duration ablation (HPSD) technique has shown promising results. Data comparing HPSD- to CB-PVI sparse. We sought investigate success rates procedural differences of HPSD-PVI vs. in patients undergoing for PAF persAF.Consecutive de novo PVI (HPSD CB) were included. A power setting 70W/7 s (70W/5 at posterior wall) a flexible...

10.1007/s00392-023-02188-2 article EN cc-by Clinical Research in Cardiology 2023-04-02

The MicraVR™ transcatheter pacing system (TPS) has been implemented into clinical routine for several years. primary recipients are patients in need VVI due to bradycardia the setting of atrial fibrillation (AF). Implantation safety and acute success have proven controlled studies registries. So far only few long-term real-life data on TPS exist. We report indication, procedure outcome from two high-volume implanting German centers.Between 2016 2019, 188 (of 303) were included. During...

10.1007/s00392-023-02286-1 article EN cc-by Clinical Research in Cardiology 2023-08-22

A 42-year-old man was admitted to hospital with, previously wrongly diagnosed, fulminant falciparum malaria, 14 days after a two-week trip Kenya. He had high fever and jaundiced, with severe anaemia thrombocytopenia. given quinine intravenously pyrimethamine/sulfadoxine (Fansidar) by mouth. developed acute renal failure increasingly cerebral symptoms, at times coma. An exchange transfusion several plasmaphereses were, therefore, performed. The symptoms quickly abated during the transfusion,...

10.1055/s-2008-1067746 article EN DMW - Deutsche Medizinische Wochenschrift 2008-03-25

Current implantable cardioverter-defibrillator (ICD) guidelines do not impose age limitations for ICD implantation (IMPL) and generator exchange (GE); however, patients (pts) should be expected to survive 1 year. With higher age, comorbidity mortality due non-sudden cardiac death increase. Thus, the benefit of therapy in elderly pts remains unclear. Mortality after IMPL or GE ≥ 75 years was assessed.

10.1007/s00399-021-00742-x article EN cc-by Herzschrittmachertherapie + Elektrophysiologie 2021-01-29

Abstract Funding Acknowledgements Type of funding sources: None. Background Several predictive scores for atrial fibrillation (AF) recurrence after ablation have been developed, only some these are validated in prospective cohorts. The value such has thus far limited, and many not compared with one another. Aims We sought to compare the seven previously described risk ((CHA2DS2 CHA2DS2-VASC, HATCH, APPLE, CAAP-AF, BASE-AF2, MB-LATER) prediction AF at 12 months ablation. Further, we aimed...

10.1093/europace/euac053.191 article EN EP Europace 2022-05-18

Cryoballoon (CB) ablation and radiofrequency (RF) are the most common techniques for pulmonary vein isolation (PVI) in patients with symptomatic atrial fibrillation (AF). An increasing number of undergoing PVI obese. To address paucity data on outcomes CB- vs. RF-based relation to body mass index (BMI) AF patients.

10.1007/s10840-022-01210-3 article EN cc-by Journal of Interventional Cardiac Electrophysiology 2022-04-12

Abstract Background Reduced biventricular pacing (BiVP) is a common phenomenon in cardiac resynchronization therapy (CRT) with impact on CRT-response and patients’ prognosis. Data treatment strategies for patients ventricular arrhythmia BiVP reduction sparse. We sought to assess the effects of BiVP. Methods In this retrospective analysis, data CRT reduced ≤ 97% due were analyzed. Catheter ablation or intensified medical was performed optimize Results included 64 consecutive (73 ± 10 years,...

10.1007/s10840-022-01259-0 article EN cc-by Journal of Interventional Cardiac Electrophysiology 2022-06-14

Abstract Background The cryoballoon (CB) has become a standard tool for pulmonary vein isolation (PVI), but the technology is limited in certain ways. A novel RF-balloon (Heliostar™, Biosense Webster, CA, USA) promises advantages of balloon combination with 3D mapping. Methods To assess procedural data and outcome, all patients undergoing PVI were included compared from consecutive CB paroxysmal AF. Results total 254 (63 ± 13 years, 54% male) included: 30 224 PVI. Baseline parameters...

10.1007/s00392-024-02401-w article EN cc-by Clinical Research in Cardiology 2024-03-13

Abstract Background Pulmonary vein isolation (PVI) is recommended in patients with symptomatic atrial fibrillation (AF) and reduced left ventricular ejection fraction (LVEF). Recently the Castle HTx (CHTx) trial showed a significant mortality reduction end stage heart failure undergoing PVI addition to optimized medical therapy (OMT) compared OMT only. Aim Objective of this analysis validate results study real world scenario. Methods All between September 2021 und 2023 referred for at our...

10.1093/europace/euae102.098 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Catheter ablation is an established therapy for ventricular tachycardia (VT) with endocardial voltage map (EVM) being the standard tool to characterize proarrhythmic substrate. However, this method limited in certain ways, especially as intramural or epicardial substrate not detected. In context, multi-detector computed tomography (MDCT) has emerged a promising alternative cardiac MRI preprocedural assessment. Purpose Data regarding MDCT- guided VT scarce, context of late...

10.1093/europace/euae102.321 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Therapy of polymorphic premature ventricular contractions (pPVC) is sometimes challenging despite improved catheter ablation options especially in patients suffering from non-ischemic cardiomyopathy. Previous studies have proven the benefit non-selective ß-blocker such as propranolol stetting electrical storm. Data for use to treat pPVC sparse. Aim We sought analyze potential setting failed or only partially successful ablation. Methods This retrospective analysis...

10.1093/europace/euae102.315 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Pulsed Field Ablation (PFA) has emerged as a promising novel technique for pulmonary vein isolation (PVI) in the setting of atrial fibrillation. First outcome data revealed comparable success rates to radiofrequency and cryoablation. However, on lesion dimensions reconnection PV after PFA potentially causing recurrence AF is sparse. We, therefore report pivotal sites ablation extend PFA-PVI. Methods All patients PFA-PVI paroxysmal or persistent at our center between...

10.1093/europace/euae102.134 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Premature ventricular contractions (PVC) arising from the left summit are a challenging arrhythmia to manage, often refractory conventional radiofrequency ablation. This study aimed investigate effectiveness of bipolar ablation as therapeutic option for PVCs originating this anatomically complex region. Methods We conducted retrospective analysis prospective registry identify patients with recurrent, symptomatic (LV) who underwent Bipolar involved use two catheters,...

10.1093/europace/euae102.333 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Transcatheter tricuspid valve (TV) repair emerged as a viable treatment option in patients with severe regurgitation and high operative risk. Although atrial fibrillation (AF) is common these patients, the prognostic value of maintenance sinus rhythm (SR) after transcatheter TV unknown. Purpose We sought to assess prevalence efficacy control strategies impacts on outcomes repair. Methods All undergoing our center between April 2017 December 2022 were included this...

10.1093/europace/euae102.043 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Pace-mapping has an important role in the ablation of idiopathic premature ventricular contractions (PVC). There is a software with automated algorithm annotating and visualizing template matching points. Automated (ATM) facilitates process may thus shorten procedure duration potentially increase success. In this randomized study we evaluate whether use compared to conventional pace-mapping (PM) influences outcomes periprocedural parameters patients undergoing PVC...

10.1093/europace/euae102.326 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Pulmonary vein isolation (PVI) is the cornerstone in treatment of atrial fibrillation (AF). Despite initially successful PVI patients experience recurrence AF mostly due to reconnection pulmonary veins (PVs). However, a certain number presents with recurrent despite durable PVI. The optimal ablation strategy for these has yet be discerned. Aim aim this study was compare outcomes different strategies persistent Methods All redo procedures from 01/2016 – 6/2022 at our...

10.1093/europace/euae102.756 article EN cc-by-nc EP Europace 2024-05-01

Abstract Background Pulmonary vein isolation (PVI) using cryoballoon (CB) ablation has comparable efficacy and safety to the gold standard of radiofrequency in treatment symptomatic atrial fibrillation (AF). Initial randomized control trials were performed Arctic Front Advance Pro™ (AFr) (Medtronic, Dublin, Ireland) CB system. Novel systems have recently become available, including POLARx™ (Px) (Boston Scientific, Marlborough, Massachusetts, USA) We aimed compare PVI Px AFr our patient...

10.1186/s42444-024-00124-7 article EN cc-by International Journal of Arrhythmia 2024-09-18

Abstract Funding Acknowledgements Type of funding sources: None. Background Mapping, using the novel omnipolar technology (OT) obtains signals displaying true voltage, real-time wavefront direction and speed, independent catheter orientation external reference. Employment OT potentially overcomes so called "bipolar blindness" (conventional bipolar electroanatomic mapping). Hence, improves substrate assessment, comprehension tachycardia mechanisms gap detection after previous ablation (CA)....

10.1093/europace/euad122.661 article EN cc-by-nc-nd EP Europace 2023-05-24

Preprocedural transoesophageal echocardiography (TEE) screening for left atrial (LA) thrombi is the standard of care in many centres performing fibrillation (AF) ablation. However, TEE imposes procedural risks patients and often challenging to implement daily practice, besides causing patient discomfort. At our centre, a novel operating procedure (SOP) was implemented, aiming identify that can be exempt from screening. We aimed assess whether this approach may reduce preprocedural TEEs...

10.1093/europace/euad279 article EN cc-by-nc EP Europace 2023-08-02
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