- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Drug Transport and Resistance Mechanisms
- Heart Failure Treatment and Management
- Patient-Provider Communication in Healthcare
- Acute Ischemic Stroke Management
- Healthcare Systems and Public Health
- Tuberculosis Research and Epidemiology
- Family Support in Illness
- Food Security and Health in Diverse Populations
- Delphi Technique in Research
- Sleep and Work-Related Fatigue
- Cardiovascular and exercise physiology
- Chronic Disease Management Strategies
- Physical Activity and Health
- Pathogenesis and Treatment of Hiccups
- Adolescent and Pediatric Healthcare
- Gut microbiota and health
- Health, psychology, and well-being
- Meta-analysis and systematic reviews
- Gastrointestinal motility and disorders
University of Calgary
2016-2024
ORCID
2021
University Health Network
2016
Toronto Western Hospital
2016
Erlanger Health System
2016
University of Alberta
2016
Royal College of Surgeons in Ireland
2016
Beaumont Hospital
2016
University of Pittsburgh Medical Center
2016
Hôpital Notre-Dame
2016
The trajectory of neurological improvement after stroke treatment is clinically likely to be an important prognostic signal. We compared the accuracy early longitudinal National Institutes Health Stroke Scale (NIHSS) measurement versus other markers severity post in predicting subjects' 90-day outcome.Data are from Endovascular for Small Core and Anterior circulation Proximal occlusion with ESCAPE trial (Endovascular Treatment Circulation Occlusion With Emphasis on Minimizing CT...
The relationship between antiseizure medications (ASMs), which improve health outcomes by controlling seizures, and health-related quality of life (HRQOL) is poorly understood may involve intermediate variables. We evaluated the potential mediators association ASMs HRQOL.Data are from an outpatient registry adult patients with epilepsy seen at Foothills Medical Center, Calgary, Alberta, Canada. Quality was measured using 10-item Life in Epilepsy, depression Neurological Disorders Depression...
Abstract Objectives Patient‐reported outcome measures (PROMs) are used widely to elicit patient's self‐appraisal of their health status and quality life. One fundamental assumption when measuring PROMs is that all individuals interpret questions about in a consistent manner. However, subgroups patients with similar condition may respond differently PROM (ie, differential item functioning [DIF]), leading biased estimates group differences on scores. Understanding these can help inform the...
No validated tools exist to assess satisfaction with epilepsy surgery. We aimed develop and validate a new measure of patient surgery, the 19-item Epilepsy Surgery Satisfaction Questionnaire (ESSQ-19).An initial 31-item was developed based on literature review, focus groups, thematic analysis, Delphi panels. The questionnaire administered twice, 4-6 weeks apart, 229 adults (≥18 years old) who underwent surgery ≥1 year earlier, at three centers in Canada one Sweden. Participants also...
ABSTRACT Objective The 19‐item Epilepsy Surgery Satisfaction Questionnaire (ESSQ‐19) is a validated and reliable post hoc means of assessing patient satisfaction with epilepsy surgery. Prediction models building on these data can be used to counsel patients. Methods ESSQ‐19 was derived 229 patients recruited from Canada Sweden. We isolated 201 (88%) complete clinical for this analysis. These were adults (≥18 years old) who underwent surgery 1 year or more prior answering the questionnaire....
ABSTRACT Purpose Exercise intervention studies for brain health can be difficult to interpret due heterogeneity in exercise intensity, duration, and adherence the intervention. This study aimed characterize these components a cohort of healthy middle-age older adults who participated prescribed 6-month supervised aerobic as part Brain Motion study. Methods Results Group-based multitrajectory analysis (GBMTA) was used variation trajectory intensity duration male female participants first 3...
Abstract Background The Seattle Angina Questionnaire (SAQ) is a widely-used patient-reported outcomes measure in patients with heart disease. This study assesses the validity and reliability of SAQ Canadian cohort individuals stable angina. Methods results Data are from Alberta Provincial Project for Outcome Assessment Coronary Heart Disease (APPROACH) registry, population-based registry who received cardiac catheterization Alberta, Canada. consists 4052 undergoing angina completed within 2...
Abstract Objective We aimed to assess the reliability and validity of single‐item global ratings (GR) satisfaction with epilepsy surgery. Methods recruited 240 patients from four centers in Canada Sweden who underwent surgery ≥1 year earlier. Participants completed a validated questionnaire on (the ESSQ‐19), plus GR twice, 4–6 weeks apart. They also questionnaires quality life, depression, health state utilities, severity disability, medical treatment social desirability. Test‐retest was...
Background: Health behaviors, such as diet and exercise, are actions individuals take that can potentially impact gastrointestinal (GI) symptoms the gut microbiota. Little is known about how health behaviors GI microbiota after anti-cancer therapies. Methods: This a secondary analysis of cross-sectional study investigated relationships between symptoms, microbiota, patient-reported outcomes in adult cancer survivors. Gut was assessed from stool samples using 16 S rRNA gene sequencing. were...
Survivors of childhood cancer face reduced fertility, which can be a significant cause for concern. Our study aimed to assess the prevalence fertility-related concerns and identify associated factors. Self-report data were collected with Long-Term Survivor Questionnaire at Alberta Children’s Hospital’s Clinic (LTSC) between January 2021 September 2023. Eligible participants diagnosed before age 21 years, ≥2 years off therapy, ≥13 old. We analyzed cross-sectionally whole sample longitudinally...
Abstract Purpose Our objectives were to identify characteristics of response shift studies using patient-reported outcomes (PROMs) that explain variability in (1) the detection and (2) magnitude effects. Methods We conducted a systematic review quantitative published before June 2023. First, two-level multivariable logistic regression models (effect- sample-levels) used probability finding effect. Second, effect sizes (standardized mean differences) was investigated with 3-level...
Our objective was to validate a Social Vulnerabilities Survey that developed identify patient barriers in the following domains: (1) salience or priority of health; (2) social support; (3) transportation; and (4) finances. Cross-sectional psychometric study.Questions for one domain (health salience) were de novo while questions other domains derived from national surveys and/or previously validated questionnaires. We tested construct (ie, convergent discriminative) validity these new through...
IntroductionCoronary Artery Disease (CAD) patients are known to report higher healthcare resource use, such as inpatient [IP] and emergency department [ED] readmissions, than the general population. We investigate if patient reported outcome measures (PROMs) improve accuracy of readmissions risk prediction models in CAD.
 Objectives ApproachPatients enrolled Alberta Provincial Project for Outcomes Assessment Coronary Heart (APPROACH) registry between 1995 2014 who received...
Abstract PurposeThe Seattle Angina Questionnaire (SAQ) is a widely used patient-reported measure of health status in patients with coronary artery disease. Comparisons SAQ scores amongst population groups and over time rely on the assumption that its factorial structure invariant (i.e., equivalent). This study evaluates measurement invariance across different demographic clinical as well time.MethodsData were obtained from Alberta Provincial Project Outcome Assessment Coronary Heart Disease...