A5086084054- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Spinal Hematomas and Complications
- Anesthesia and Pain Management
- Surgical site infection prevention
- Opioid Use Disorder Treatment
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Analysis
- Shoulder Injury and Treatment
- Pain Management and Opioid Use
- Infectious Diseases and Tuberculosis
- Hip and Femur Fractures
- Clinical practice guidelines implementation
- Patient Satisfaction in Healthcare
- Pregnancy-related medical research
- Case Reports on Hematomas
- Venous Thromboembolism Diagnosis and Management
- Global Health Workforce Issues
- Emergency and Acute Care Studies
- Management of metastatic bone disease
- Orthopaedic implants and arthroplasty
Rothman Orthopaedics
2019-2025
Rothman Institute
2015-2024
Thomas Jefferson University Hospital
2017-2024
Thomas Jefferson University
2015-2024
Brigham and Women's Hospital
2024
Georgetown University
2024
Stryker (United States)
2019-2023
Medtronic (Ireland)
2019-2023
Stryker (United Kingdom)
2023
Santa Rosa Junior College
2023
Cervical spondylotic myelopathy is increasingly prevalent in the elderly and leading cause of spinal cord dysfunction this population. Laminectomy with fusion laminoplasty halt progression these patients; however, both procedures have well-documented complications associated morbidity it unclear which might be most advantageous.We therefore compared pain, function alignment patients who underwent laminectomy to those for treatment multilevel cervical myelopathy.We performed a retrospective...
Background: Perioperative allogeneic red blood cell transfusion is a risk factor for surgical site infection. The purpose of this study was to determine if the volume perioperative influences infection following lumbar spine procedures. Methods: A retrospective matched case control performed by reviewing all patients who had undergone surgery at our institution from 2005 2009. Surgical infections (spinal or iliac crest) were identified, within thirty days procedure. Controls cohort according...
Study Design: Prospective survey study. Objective: To address a gap that exists concerning ChatGPT’s ability to respond various types of questions regarding cervical surgery. Summary Background Data: Artificial Intelligence (AI) and machine learning have been creating great change in the landscape scientific research. Chat Generative Pre-trained Transformer(ChatGPT), an online AI language model, has emerged as powerful tool clinical medicine Previous studies demonstrated appropriate reliable...
Introduction: The risks and benefits of extending posterior cervical decompression fusion (PCDF) constructs across the cervicothoracic junction (CTJ) remain controversial. Previous studies have used fusions beginning at different levels varying in construct length. There are no that examine effect crossing CTJ on opioid consumption. This study aims to compare short-term long-term postoperative outcomes among patients undergoing PCDF C3 ending C7, T1, or T2. Methods: Adult who underwent...
Study Design. Retrospective cohort review. Objective. The objective of this study was to identify depression using the Mental Component Score (MCS-12) Short Form-12 (SF-12) survey and correlate with patient outcomes. Summary Background Data. impact preexisting depressive symptoms on health-care related quality life (HRQOL) outcomes following lumbar spine fusion is not well understood. Methods. Patients undergoing between one three levels at a single center, academic hospital were...
Study Design: This was a prospective cohort study. Objective: The objective of this study to design and test novel spine neurological examination adapted for telemedicine. Summary Background Data: Telemedicine is rapidly evolving technology associated with numerous potential benefits health care, especially in the modern era value-based care. To date, no studies have assessed whether. Methods: Twenty-one healthy controls 20 patients cervical or lumbar spinal disease (D) were prospectively...
Retrospective matched cohort study.To compare mortality in elderly patients with odontoid fractures after operative and nonoperative treatment. In addition, to evaluate potential factors that may increase the risk of geriatric population fracture.Odontoid represent most common cervical spine fracture over 70. this controversy exists as optimal treatment fractures, especially type II fractures.A retrospective review all 75 years age or older at our institution from 1996 2010 was performed....
Study Design. A retrospective review of radiographic data and functional outcomes. Objective. The aim this study was to evaluate whether myelopathy symptom severity upon presentation corresponds sagittal plane alignment or nonmyelopathy symptoms, such as pain, in patients with cervical spondylotic (CSM). Summary Background Data. Cervical balance is an important parameter the outcome surgical reconstruction. However, effect on who have not undergone spine surgery well defined. Methods....
Objectives: The purpose of this study was to critically evaluate the efficacy single screw and washer fixation in comparison with other methods for securing olecranon osteotomies. hypothesis is that a safe effective means osteotomy fusion complication rates similar fixation. Design: Retrospective review. Setting: Two Level I Urban Trauma Centers. Patients/Participants: Patients were treated within last 20 years received 1 4 types (screw alone, augmented tension band, band or plate screws)...
Study Design. Retrospective comparative study. Objective. The purpose of this study was to investigate whether preoperative depressive symptoms, measured by mental component score the Short Form-12 survey (MCS-12), influence patient-reported outcome measurements (PROMs) following an anterior cervical discectomy and fusion (ACDF) surgery for degeneration. Summary Background Data. There is a paucity literature regarding depression PROMs ACDF degenerative disease. Methods. Patients who...
Currently, no studies have assessed what effect the presence of both anxiety and depression may on patient-reported outcome measurements (PROMs) compared to patients with a single or mental health diagnosis.Patients undergoing 1- 3-level lumbar fusion at academic hospital were retrospectively queried. Anyone and/or was identified using an existing clinical diagnosis in medical chart. Patients separated into 3 groups: (NDA), alone (DOA), combined (DAA). Absolute PROMs, recovery ratios,...
A retrospective cohort study.To determine whether the 11-item modified frailty index (mFI) is associated with readmission rates, complication revision or differences in patient-reported outcome measures (PROMs) for patients undergoing posterior cervical decompression and fusion (PCDF).mFI incorporates preexisting medical comorbidities dependency status to physiological reserve. Based on previous literature, it may be used as a predictive tool identifying postoperative clinical surgical...
The objective of this study was to evaluate patient and surgical factors that predict increased overall lumbar lordosis (LL) segmental correction following a minimally invasive lateral interbody fusion (LLIF) procedure.A retrospective review conducted all patients who underwent one- or two-level LLIF. Preoperative, initial postoperative, 6-month postoperative measurements LL, lordosis, anterior disc height, posterior height were collected from standing radiographs for each patient. Cage...
AMP-forming acetyl-CoA synthetase [ACS; acetate:CoA ligase (AMP-forming), EC 6.2.1.1] catalyzes the activation of acetate to in a two-step reaction. This enzyme is member adenylate-forming superfamily that includes firefly luciferase, nonribosomal peptide synthetases, and acyl- aryl-CoA synthetases/ligases. Although structures several members demonstrate these enzymes have similar fold domain structure, low sequence conservation diversity substrates utilized limited utility understanding...
Study Design: Retrospective cohort study.Purpose: To compare radiographic outcomes between unilateral and bilateral cage placement in transforaminal lumbar interbody fusions (TLIF) to determine if the rate of fusion at 1-year postoperative point was different patients who received versus cages.Overview Literature: There is no clear evidence dictate whether or cages promote superior surgical TLIF.Methods: Patients >18 years old underwent primary one- two-level TLIFs our institution were...
Pseudarthrosis following spinal fusion is a complication that frequently requires revision surgery. Reported rates of pseudarthrosis after surgical site infection (SSI) range from 30% to 85%, but few studies have identified as an independent risk factor for its development. The purpose this study was determine the incidence clinically symptomatic in patient who developed SSI lumbar and identify factors associated with development.This retrospective review prospectively collected database....
Retrospective study.To elucidate an association between preoperative lumbar epidural corticosteroid injections (ESI) and infection after spine surgery.ESI may provide diagnostic therapeutic benefit; however, concern exists regarding whether ESI increase risk of postoperative infection.Patients who underwent decompression alone or fusion procedures for radiculopathy stenosis 2000 2017 with 90 days follow-up were identified by ICD/CPT codes. Each cohort was categorized as no ESI, less than 30...
➤ Despite being a social construct, race has an impact on outcomes in musculoskeletal spine care.➤ Race is associated with other determinants of health that may predispose patients to worse outcomes.➤ The literature limited its understanding the causes race-related outcome trends.➤ Efforts mitigate disparities care require individual, institutional, and national initiatives.