Д. М. Кучин

ORCID: 0000-0002-4148-2953
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Gastric Cancer Management and Outcomes
  • Pancreatic function and diabetes
  • Pancreatitis Pathology and Treatment
  • Biliary and Gastrointestinal Fistulas
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Diabetes Management and Research
  • Cancer Immunotherapy and Biomarkers
  • Cutaneous Melanoma Detection and Management
  • Neuroblastoma Research and Treatments
  • Cannabis and Cannabinoid Research
  • Multiple and Secondary Primary Cancers
  • Melanoma and MAPK Pathways
  • Gallbladder and Bile Duct Disorders
  • Amoebic Infections and Treatments

Privolzhsky Research Medical University
2020-2024

Nizhny Novgorod Regional Clinical Oncology Center
2019

To evaluate the immediate results of enucleation pancreatic neuroendocrine tumors (pNETs).The (pNETs) were analyzed in 95 patients between 2016 and 2021. Functioning (mean size 16.8 mm) found 70 patients, non-functioning 25 - patients. Intraparenchymal 48 people, extraorganic lesion 47 patients.There 262 with pNETs who underwent various surgeries Various resections performed 167 (63.8%) cases, enucleations (36.2%) Traditional surgical approach was used 65 Pancreatic fistula occurred 21 (type...

10.17116/hirurgia202302113 article RU Pirogov Russian Journal of Surgery 2023-01-01

Цель. Анализ ранних и поздних сосудистых осложнений (тромбозы, кровотечения), их причин тактики лечения у больных после ПДР, в том числе с сосудистой реконструкцией. Материалы методы. Проведен ретроспективный анализ технических особенностей операции послеоперационного периода 595 пациентов, которым период 2006 по 2020 гг была выполнена панкреатодуоденальная резекция. Резекции магистральных сосудов ходе выполнены 180 (30,3%) пациентов. Оценивали характер, количество тяжесть развившихся...

10.37469/0507-3758-2024-70-2-360-367 article RU cc-by Voprosy Onkologii 2024-05-06

Chronic pancreatitis (CP) is a quite common disease with an annual incidence of up to 30 new cases per 100,000 persons in Russia, and 9.6 abroad. Idiopathic associated genetic mutations ranks second frequency. When conservative therapy ineffective, surgical intervention considered. Total pancreatectomy reduces pain, but leads pancreatogenic diabetes mellitus. In case hereditary caused by the PRSS1, CFTR, SPINK1 genes, becomes advisable, including for prevention pancreatic cancer. Isolation...

10.17691/stm2024.16.6.05 article EN Sovremennye tehnologii v medicine 2024-12-27

Primary malignant melanoma of the esophagus is a rare disease with an aggressive course and poor prognosis. This article presents review world literature on this specific disease, including incidence statistics, modern principles diagnosis treatment, as well clinical case patient resectable esophageal melanoma.

10.18027/2224-5057-2019-9-4-42-48 article EN cc-by Malignant tumours 2020-04-11

Aim. To develop and implement a method for isolating the islets of Langerhans from pancreatic tissue after pancreatectomy with islet autotransplantation. Materials Methods. The study used ten Wiesenau miniature pig pancreases, 30 Wistar rat eight resected human five pancreases extensive resection or pancreatectomy. Results. Islets completely devoid experimental animals’ acinar were obtained. When using protocol mechanical isolation, efficiency in humans animals was 50%. research proved that...

10.16931/1995-5464.2022-3-46-54 article EN Annaly khirurgicheskoy gepatologii = Annals of HPB surgery 2022-09-20

The review includes the results of analytical research on problem application pancreatic islet encapsulation technologies for compensation type 1 diabetes. We present a modern technologies, approaches to strategies, insulin replacement technologies: auto-, allo- and xenotransplantation; prospects cell therapy insulin-dependent conditions; β-cell encapsulation, possibilities optimization biomaterials increase survival transplanted cells reduce adverse consequences recipient. main problems...

10.15825/1995-1191-2021-4-95-109 article EN cc-by Russian Journal of Transplantology and Artificial Organs 2021-10-22

Aim. To analyze the complications of liver and pancreas surgeries, including infectious complications, to describe evolution microbial flora in hepatopancreatobiliary surgery unit. Materials methods. The study involved 650 patients who underwent pancreatoduodenectomy 1253 after resection. Types preoperative biliary drainage were evaluated terms their influence on treatment results. incidence nature postoperative bile leakage studied. included an analysis unit for 10 years. Results. rate...

10.16931/1995-5464.2023-4-71-80 article EN Annaly khirurgicheskoy gepatologii = Annals of HPB surgery 2023-12-14

The aim of the study was to evaluate efficacy combined treatment for well-differentiated pancreatic neuroendocrine tumors according data provided by a specialized center.Materials and Methods.Treatment 40 patients with assessed.All underwent surgical removal primary tumor.Liver metastases (stage IV) were diagnosed in 14 patients, postoperative courses hepatic artery chemoembolization performed 12 10 them had cancer.Results.Good survival rates stage IV disease (n=12) are comparable those...

10.17691/stm2019.11.3.10 article EN Sovremennye tehnologii v medicine 2019-09-01

A description of a rare clinical observation pancreatic VIPoma is presented. Submitted literature review. The difficulties preoperative diagnosis, as well the effectiveness surgical treatment are shown.

10.16931/1995-5464.20201113-118 article EN Annaly khirurgicheskoy gepatologii = Annals of HPB surgery 2020-03-18

Purpose . To identify major factors affecting the overall survival (OS). select cohort of patients with best prognosis. Materials and methods A retrospective analysis included data 268 patients, 128 men 140 women, median age 59±10,53 (30 to 83) years. For multivariate survival, were selected who underwent pancreaticoduodenectomy (PD) for ductal adenocarcinoma pancreatic head. Results Our study demonstrated that histologically verified vascular invasion (detected only in 30 % PD resection...

10.18027/2224-5057-2021-11-1-20-28 article EN cc-by Malignant tumours 2021-07-26
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