Dilan ÇETİNAVCI

ORCID: 0000-0002-4148-7711
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Research Areas
  • Chemotherapy-induced organ toxicity mitigation
  • COVID-19 Impact on Reproduction
  • Metabolism, Diabetes, and Cancer
  • Innovations in Medical Education
  • Saffron Plant Research Studies
  • Pregnancy and preeclampsia studies
  • Medical Malpractice and Liability Issues
  • Potato Plant Research
  • Health Education and Validation
  • Film in Education and Therapy
  • Pediatric Hepatobiliary Diseases and Treatments
  • Drug Transport and Resistance Mechanisms
  • Anorectal Disease Treatments and Outcomes
  • Reproductive Biology and Fertility
  • Endometriosis Research and Treatment
  • Empathy and Medical Education
  • Circadian rhythm and melatonin
  • Clinical Reasoning and Diagnostic Skills
  • Cancer-related Molecular Pathways
  • Fibroblast Growth Factor Research
  • Natural Compound Pharmacology Studies
  • Liver physiology and pathology
  • Molecular Biology Techniques and Applications
  • Nigella sativa pharmacological applications
  • Proteoglycans and glycosaminoglycans research

Muğla University
2021-2025

The use of YouTube videos for educational purposes has been increasingly popular. quality and accuracy the information level these should be checked by expert trainers. This study aims to evaluate content, functionality on Histology Embryology measure their usefulness. In study, searches were performed using keywords "Histology" "Embryology" in search tab. Quality content evaluated Video Power Index (VPI), modified DISCERN scale, JAMA Global Scale (GQS). Videos categorized SPSS software was...

10.1111/ahe.12859 article EN Anatomia Histologia Embryologia 2022-09-08

Doxorubicin (Dox), an anthracycline antibiotic, is a chemotherapeutic drug for several cancer treatments. However, its clinical usage has been restricted because of severe side effects, including nephrotoxicity. This study aimed to demonstrate the possible nephroprotective effects crocin (Cr) against Dox-induced oxidative stress, renal inflammation, morphology and transforming growth factor-β (TGF-β) signalling pathways in Dox-exposed rats. Hence, rats were injected 15 d consecutively with...

10.1080/14786419.2024.2344180 article EN Natural Product Research 2024-04-25

Abstract The study aimed to determine the CCl 4 -induced liver fibrosis model in pinealectomized rats and biochemically, immunohistochemically, histopathologically investigate therapeutic effect of melatonin on fibrosis. surgical procedure for pinealectomy was performed at beginning study, sham were administered dissolved corn oil (1:1) alone every other day induce or together with (10 mg/kg) therapy 15 days. Melatonin is an essential agent offers alternative strategy by suppressing...

10.1007/s10753-024-02101-7 article EN cc-by Inflammation 2024-07-15

Purpose: Doxorubicin (DOX) is a wide-spectrum antibiotic used for chemotherapy. Its side effects limit treatment. Crocin one of the carotenoids that has both anti-inflammatory and antioxidant activities. We aimed to evaluate crocin against doxorubicin-induced testicular damage in rats. Materials Methods: Forty Wistar rats were divided into four groups. Group 1: Control, 2: Crocin, 3: DOX, 4: DOX+Crocin (n=10, all). Testis tissues stained with Hematoxylin-Eosin. The diameters seminiferous...

10.17826/cumj.1420141 article EN Çukurova medical journal (Online)/Çukurova medical journal 2024-06-27

Purpose: Cyclophosphamide (CP) is an antineoplastic agent. It used in the treatment of many types cancer. Rosmarinic acid (RA) exhibits remarkable biological activities such as anti-inflammatory, antitumor, antibacterial, and antimicrobial effects. This study aimed to evaluate effect rosmarinic against CP-induced nephrotoxicity.
 Materials Methods: Eighteen male Sprague Dawley rats were randomly divided into 3 equal groups; Sham group (n=6): 0.9% saline solution/8 days/oral gavage +...

10.17826/cumj.1317508 article EN Çukurova medical journal (Online)/Çukurova medical journal 2023-09-25

Aim: Cisplatin is one of the effective antineoplastic drugs widely used in treatment many types cancer.Cisplatin has harmful effects such as nephrotoxicity, ototoxicity and cardiomyopathy.Quercetin an antioxidant flavonoid group.In this study, it was aimed to investigate therapeutic quercetin against cisplatin-induced kidney damage rats.Materials Methods: Twenty-eight male Wistar albino rats were randomly selected divided into 4 groups: Group 1: Control (no application), 2: Quercetin (25...

10.4274/nkmj.galenos.2022.24865 article EN cc-by-nc-nd Namık Kemal Tıp Dergisi 2022-06-22

Aim: Breast cancer is the most common malignancy in women. This disease a critical public health problem and further research at molecular level would define its prognosis specific treatment. Phenformin an antidiabetic agent. Recent studies showed that it should be considered as potential agent for prevention treatment of cell lines. study aimed to investigate antiproliferative effect phenformin on MDA-MB-231 MCF-7 breast Materials Methods: lines were used study. Experimental groups; control...

10.37990/medr.1137136 article EN Medical Records 2023-01-05

Prostat kanseri, erkeklerde kansere bağlı ölümlerin ikinci en sık nedenidir. Kemoterapötiklere direnç gelişmesi nedeniyle prostat kanserini tedavi etmek için yeni ilaçlara ihtiyaç vardır. Fenformin biguanid grubu antidiyabetik bir ilaçtır ve antikanserojen etkileri de Fibroblast büyüme faktörü reseptörü 2 (FGFR2), hücre proliferasyonunu farklılaşmasını destekleyen membran reseptörüdür. Çalışmamızda; PC-3 insan kanseri hücrelerinde fenforminin FGFR2 üzerinden etkilerinin araştırılması...

10.47572/muskutd.1024832 article TR Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2023-08-05

Aim: Visual arts have been incorporated into medical education in different ways. The successfull enhancing tolerance for ambiguity, fostering, empathy, and holistic views of students all levels. Physical examination is a fundamental part clinical diagnosis. A proper observation can provide critical information the diagnostic evaluation accuracy treatment. Special Study Module (SSM) an educational method which are given opportunity to study, research, experience their own areas interest....

10.25282/ted.1249701 article EN Tıp Eğitimi Dünyası 2023-08-28

Amaç: Preeklampsi; gebelikte ortaya çıkan hipertansiyon, proteinüri, artmış damar hasarı ve geçirgenliği yüzeyel plasenta istilası ile karakterize multisistemik bir hastalıktır.Neuregulin-1 (NRG-1), embriyogenez, anjiyogenez, sinir sistemi gelişimi, miyogenez, gonadogenez için önemli olan liganddır.Çalışmamızda NRG-1'in preeklampsideki öneminin ışık mikroskobik olarak incelenmesi

10.4274/nkmj.galenos.2023.19970 article TR cc-by-nc-nd Namık Kemal Tıp Dergisi 2023-12-08

A new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) first appeared in Wuhan, China December 2019, causing an infectious disease called 'coronavirus 2019' (COVID-19) (1).While many countries continue to fight infections caused by COVID-19, they have stepped up the development of vaccines provide immunity against virus and stop transmission (2)."Vaccine hesitancy" that defined as reluctance receive safe recommended available vaccines, was already a growing concern prior COVID-19...

10.15296/ijwhr.2022.21 article EN International Journal of Women s Health and Reproduction Sciences 2022-02-14

Objective: Covid-19 disease has spread rapidly across the world since its first appearance in 2019. At beginning of pandemic, was thought to affect only respiratory system, although it been realized that causes numerous transient or permanent problems various body systems. One these effects involves reproductive system.
 Several studies have investigated on female and male Embryological life depends fertilization a healthy mature oocyte, sperm, continuation pregnancy. The purpose this...

10.36472/msd.v8i9.605 article EN Medical Science and Discovery 2021-09-21
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