Yixiang Cao

ORCID: 0000-0002-4148-9151
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Nanoparticle-Based Drug Delivery
  • RNA Interference and Gene Delivery
  • Nanoplatforms for cancer theranostics
  • Immune cells in cancer

State Key Laboratory of Digital Medical Engineering
2022-2024

Southeast University
2022-2024

CXC chemokine receptor 4 (CXCR4) is a promising therapeutic target. Previous studies have shown that intracellular delivery of siRNA to knockdown CXCR4 expression in cancer cells an effective strategy. To prepare efficient magnetic nucleic acid carriers, it now necessary improve the endocytosis efficiency PEGylated nanoparticles. In our work, Heptafluorobutyryl-polyethylene glycol-polyethyleneimine (FPP) was first prepared and then used coat nanoparticles (MNPs) obtain nanocarriers FPP@MNPs....

10.3390/nano12101692 article EN cc-by Nanomaterials 2022-05-16
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