A5082524771- Cerebral Palsy and Movement Disorders
- Medical Practices and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Balance, Gait, and Falls Prevention
- Diabetic Foot Ulcer Assessment and Management
- Biomedical and Chemical Research
- Cardiovascular and exercise physiology
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Scoliosis diagnosis and treatment
- Shoulder Injury and Treatment
- Pain Management and Treatment
- Cardiovascular Function and Risk Factors
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Infant Development and Preterm Care
- Diet and metabolism studies
- Ophthalmology and Eye Disorders
- Martial Arts: Techniques, Psychology, and Education
- Tryptophan and brain disorders
- Stroke Rehabilitation and Recovery
- Medical and Biological Sciences
- Ergonomics and Musculoskeletal Disorders
- Spinal Cord Injury Research
- Laser Applications in Dentistry and Medicine
- Long-Term Effects of COVID-19
Jena University Hospital
2016-2025
Friedrich Schiller University Jena
2018-2023
Background: Reduced exercise capacity in patients with heart failure (HF) could be partially explained by skeletal muscle dysfunction. We compared function, structure, and metabolism among clinically stable outpatients HF preserved ejection fraction, reduced healthy controls (HC). Furthermore, the molecular, metabolic, clinical profile of endurance was described. Methods: Fifty-five participants were recruited prospectively at University Hospital Jena (17 18 20 HC). All underwent...
Zusammenfassung Für das vorherrschende Symptom Fatigue im Rahmen des Post-COVID-Syndroms (PCS) existieren weiterhin nur eingeschränkte Behandlungsstrategien. Hydrotherapeutische Verfahren zeigten bei anderen Ursachen der positive Effekte. Das primäre Ziel ist es erstmals objektivierbare Daten mittels HRV zur Wirksamkeit von Kniegüssen nach Kneipp auf die Fatique Post-COVID zu generieren. Personen mit relevanter Fatigue, gemessen Chalder Skala, wurden in Studie eingeschlossen. Die...
Aims: Metabolic and structural perturbations in skeletal muscle have been found patients with heart failure (HF) both preserved (HFpEF) reduced (HFrEF) ejection fraction association endurance (RME). We aimed the current study to create phenotypes for RME HFpEF compared HFrEF according their metabolomic profiles test potential of Kynurenine (Kyn) as a marker RME. Methods: Altogether, 18 HFrEF, 17 HFpEF, 20 healthy controls (HC) were prospectively included study. The following tests performed...
Walking disabilities negatively affect inclusion in society and quality of life increase the risk for secondary complications. It has been shown that external feedback applied by therapists and/or robotic training devices enables individuals with gait abnormalities to consciously normalize their pattern. However, little is known about effects a technically-assisted over ground therapy. The aim this study was assess whether automatic real-time provided shoe-mounted inertial-sensor-based...
Impaired tissue oxygenation is the key pathomechanism in development of organ dysfunction shock; mitochondrial impairment can aggravate condition. However, measuring directly and non-invasively still poses a clinical challenge. A novel device (COMET) allows assessment oxygen metabolism using Protoporphyrin IX Triplet State Lifetime Technique (PpIX-TSLT). Critically ill patients, especially sepsis, often exhibit oedema which may interfere with COMET measurement. Furthermore, patients'...
Background Numerous wearables are used in a research context to record cardiac activity although their validity and usability has not been fully investigated. The objectives of this study is the cross-model comparison data quality at different realistic use cases (cognitive physical tasks). recording expressed by ability accurately detect QRS complex, amount noise data, RR intervals. Methods Five ECG devices (eMotion Faros 360°, Hexoskin Hx1, NeXus-10 MKII, Polar RS800 Multi SOMNOtouch NIBP)...
Patients with heart failure (HF) suffer from reduced quality-of-life (QoL). We aimed to compare QoL, depression, and anxiety scores among outpatients preserved (HFpEF) (HFrEF) ejection fraction non-HF controls its relationship coordination capacity.Fifty-five participants were recruited prospectively at the University Hospital Jena, Germany (17 HFpEF, 18 HFrEF, 20 controls). All underwent echocardiography, cardiopulmonary exercise testing (CPET), 10 m walking test (10-MWT), isokinetic muscle...
Abstract Treatment modalities of spinal pain patients are discussed diversely, and different multimodal therapy programs have been developed. Purpose the present study was to evaluate outcome effectiveness an inpatient interdisciplinary treatment program. This prospective multicentre clinical trial has performed with from orthopedic hospitals receiving a functional musculoskeletal pathway. Outcome measures were intensity back-specific function (Oswestry Disability Index) before (T1) after...
Abstract Objective The aim of the study was evaluation effects a single manual medicine treatment (SMMT) for infants with postural and motor asymmetries in upper cervical asymmetry disorder respectively kinematic imbalance due to suboccipital strain (KISS). Methods Design: Multicentre double-blind randomised Subjects/Setting: 202 at age 14–24 weeks movement findings were examined four centres using standardized 4-item Symmetry-Score (points: 4=symmetric 17=asymmetric). inclusion criterion...
Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good function an impaired proprioception may result insecure gait. Limited internal afferent feedback (FB) can be compensated by provision of external FB therapists or technical systems. Progress computational power motion analysis systems allows for implementation instrumented real-time FB. The aim this study was test if individuals iSCI normalize their gait kinematics during more...
Background: Mitochondria are the key players in aerobic energy generation via oxidative phosphorylation. Consequently, mitochondrial function has implications on physical performance health and disease ranging from high sports to critical illness. The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) allows vivo measurements of oxygen tension (mitoPO 2 ). Hitherto, few data exist relation metabolism ergospirometry-derived variables during performance. This study investigates...
Abstract Background There are different therapeutic approaches to persistent positional preference (kinematic imbalance due suboccipital strain, KISS) in infants. no evidence-based or controlled studies investigating the effect of manual medicine treatment children aged 3–6 months, particularly combination with a home exercise programme. The presented monocentric study on one-time infants 14–24 exhibiting these symptoms aims close this gap. Methods This comprises double-blind trial and...
Abstract Aims Both left atrial strain (LAS) and skeletal muscle endurance demonstrate a linear relationship to peak VO 2 . Less is known about the between central (cardiac) peripheral (muscle endurance) limitations of exercise capacity in patients with heart failure (HF). We investigated this using novel cardiac markers such as LAS emptying fraction (LAEF). Methods results analysed echocardiographic measurements, cardiopulmonary testing (CPET), isokinetic function 55 subjects HF controls [17...
Measurements of exercise‐induced metabolic changes, such as oxygen consumption, carbon dioxide exhalation or lactate concentration, are important indicators for assessing the current performance level athletes in training science. With exercise‐limiting processes occurring loaded muscles, 31 P‐MRS represents a particularly powerful modality to identify and analyze corresponding training‐induced alterations. Against this background, study aimed adaptations after an exhaustive exercise two...
Vaginal surface electromyography (sEMG) is a tool used for the diagnosis and therapeutic intervention of urinary incontinence. Current sEMG systems differ in regard to electrode arrangement data reproducibility. The aim this study was determine intrasession, intraday, interday reliabilities parameters using probe with circumferential electrode-position.The maximum isometric voluntary contractions (MVC) pelvic floor muscles were assessed 19 healthy continent women. Three that are describe...
Zusammenfassung Die motorische Differenzierungsfähigkeit ist eine Eigenschaft, welche essentiell für die Bewegungsausführung ist. Der Zielschritt-Test eröffnet Möglichkeit diese Fähigkeit zu überprüfen und einzuschätzen. Dieser Test wird hier vorgestellt.
Many post-COVID patients suffer from dyspnea on exertion. To visualize exercise-induced dyspnea, a patient and healthy volunteer underwent an exercise test treadmill under stress relevant to everyday life monitored by electrical impedance tomography (EIT).The lung-healthy showed even ventilation distribution throughout the assessment, large ventilated area, butterfly-like lung shape with convex rim. The clear differences in area compared control subject. During exercise, constantly changing...
In Deutschland leiden ca. 5–8 Millionen Menschen an chronischen Schmerzen. Dies kostet den Staat 20 Milliarden €/Jahr. Eine wenig untersuchte nichtmedikamentöse Schmerztherapie stellt die Anwendung von Leistungslasern dar. der vorliegenden Studie wurde Wirksamkeit Ultraschallanwendungen im Vergleich zu Leistungslaser hinsichtlich Schmerzintensität untersucht. Es wurden Patienten des Instituts für Physiotherapie Universitätsklinikums Jena rekrutiert, unter Beschwerden LWS oder Schulterregion...
Hintergrund: Seit 1960 erstmals Laserlicht erzeugt werden konnte, etablierte sich diese Lichtform auch zunehmend in der Medizin. Laser finden breite Anwendung Diagnostik und Therapie. In Physiotherapie Soft- Leistungslaser zur Behandlung eingesetzt.