Christina Lemhöfer

ORCID: 0000-0002-6206-4064
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • COVID-19 and Mental Health
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Medical Practices and Rehabilitation
  • Biomedical and Chemical Research
  • Intensive Care Unit Cognitive Disorders
  • Health and Medical Studies
  • Medical and Health Sciences Research
  • Myofascial pain diagnosis and treatment
  • Musculoskeletal Disorders and Rehabilitation
  • COVID-19 Clinical Research Studies
  • Musculoskeletal pain and rehabilitation
  • Tryptophan and brain disorders
  • Therapeutic Uses of Natural Elements
  • Total Knee Arthroplasty Outcomes
  • Clinical practice guidelines implementation
  • Cerebral Palsy and Movement Disorders
  • Spine and Intervertebral Disc Pathology
  • Respiratory Support and Mechanisms
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Multiple Sclerosis Research Studies
  • German Literature and Culture Studies
  • Family and Disability Support Research
  • Telemedicine and Telehealth Implementation

Jena University Hospital
2021-2025

Friedrich Schiller University Jena
2023-2025

Laboratoire CarMeN
2025

Université Claude Bernard Lyon 1
2025

Hospices Civils de Lyon
2025

Centre Hospitalier Annecy Genevois
2025

Hôpital Nord
2025

Centre Hospitalier Métropole Savoie
2025

Inserm
2025

Institut National des Sciences Appliquées de Lyon
2025

In COVID-19 survivors a relatively high number of long-term symptoms have been observed. Besides impact on quality life, these (now called Post-COVID-Syndrome) may an functioning and also hinder to participation in social life affected people. However, little is known about developing such syndrome for patients with mild moderate who did not need hospitalization or intensive care.A cross-sectional study 1027 was performed two communities Bavaria, Germany. The Rehabilitation-Needs-Survey...

10.1186/s12995-021-00337-9 article DE cc-by Journal of Occupational Medicine and Toxicology 2021-10-07

Following SARS-CoV-2 virus infection, patients may suffer from long-lasting symptoms regardless of disease severity. Preliminary results show limitations in health-related quality life (HRQoL). The aim this study is to a possible change depending on the duration since infection and accumulation symptoms. Additionally, other influencing factors will be analyzed.The population consisted (18-65 years) presenting Post-COVID outpatient clinic University Hospital Jena, Germany, between March...

10.1007/s11136-023-03369-2 article EN cc-by Quality of Life Research 2023-03-03

COVID-19 can result in a broad spectrum of dysfunctions, some which may persist for long periods, requiring long-term rehabilitation. A comprehensive screening tool is therefore necessary to identify these needs. To date, no data exist on satisfaction with medical and therapeutic interventions terms quality quantity. The aim this study develop survey use patients during after the end acute phase disease.Following definition dimensions by group experts, literature search, proven instruments...

10.2340/16501977-2818 article EN cc-by-nc Journal of Rehabilitation Medicine 2021-01-01

Some patients experience long-term sequelae after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, despite a present post-COVID condition, defined as "any symptom lasting longer than 12 weeks," only subset of search for medical help and therapy.We invited all adults positive real-time polymerase chain reaction (RT-PCR) SARS-CoV-2 between March 2020 September 2021 (n = 4091) in the city Jena to answer standardized questionnaire including demographic...

10.1007/s15010-022-01886-9 article EN cc-by Infection 2022-07-22

A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority complains about neuropsychological Additionally, a subgroup fulfills diagnostic criteria for ME/CFS. We analyzed registry all presenting in out-patients clinic at German university center. For with more than one visit, changes reported first to second visit were analyzed. total 1022 included study, 411 them had visit. 95.5%...

10.1007/s00406-023-01661-3 article EN cc-by European Archives of Psychiatry and Clinical Neuroscience 2023-08-16
Katharina S. Appel Carolin Nürnberger Thomas Bahmer Christian Förster Maria Cristina Polidori and 95 more Mirjam Kohls T. Kraus Nora Hettich-Damm Julia Petersen Sabine Blaschke Isabel Bröhl Jana Butzmann Hiwa Dashti Jürgen Deckert Michael Dreher K Fiedler Carsten Finke Ramsia Geisler Frank Hanses Sina M. Hopff Björn‐Erik Ole Jensen Margarethe Konik Kristin Lehnert Susana M. Nunes de Miranda Lazar Mitrov Olga Miljukov Jens‐Peter Reese Gernot Rohde Margarete Scherer Kristin Tausche Johannes Tebbe Jörg Janne Vehreschild Florian Voit Patricia Wagner Martin Weigl Christina Lemhöfer Khaled O. Alsaad Eckard Hamelmann Holger Heidenreich Claudia Hornberg N. S. A. Kulamadayil-Heidenreich P. Maasjosthusmann A. Muna M. Ruwe Christoph Stellbrink N. Buechner Y. Dashti Carl F. Tessmer Barbara Laumerich Ingmar Silberbaur Stephen O. Bader Michael Engelmann André Fuchs A. Langer Bruno Maerkl H Messmann Anna Muzalyova Christoph Roemmele Heidi Altmann Reinhard Berner Svenja Dreßen Tobias Koch Dirk Lindemann Kristin Seele Peter M. Spieth Nicole Toepfner Simone von Bonin Torsten Feldt Verena Keitel Alexander Killer Lisa Knopp Tom Luedde M. Lutterbeck Martha Paluschinski John Pereira Jörg Timm Detlef Kraska Andreas E. Kremer Moritz Leppkes Jonathan M. Mang M. F. Neurath Hans U. Prokosch Jochen Schmid Marcel Vetter Carsten Willam Kathrin Wolf Christophe Arendt Carla Bellinghausen Sabine Cremer Adrian Groh A. Gruenewaldt Yascha Khodamoradi Svenja Klinsing Maria J. G. T. Vehreschild Thomas J. Vogl Marylyn M. Addo Maher Almahfoud Alexander Engels Dominik Jarczak Melanie Kerinn

Abstract Purpose The objective examination of the Post-COVID syndrome (PCS) remains difficult due to heterogeneous definitions and clinical phenotypes. aim study was verify functionality correlates a recently developed PCS score. Methods score applied prospective, multi-center cross-sectoral cohort (in- outpatients with SARS-CoV-2 infection) "National Pandemic Cohort Network (NAPKON, Germany)". Symptom assessment patient-reported outcome measure questionnaires were analyzed at 3 12 months...

10.1007/s15010-024-02226-9 article EN cc-by Infection 2024-04-08

Abstract Background Post-COVID-19 syndrome (PCS) prevalences range from 10% up to 45%, caused by heterogeneous definitions, different study designs and survey methods, sometimes misattribution of unrelated comorbidities PCS. First correlations between PCS health-related quality life (HrQoL) are described. This analyzes the course differences PCS-related symptoms associated HrQoL in a large multicenter cohort.Table 1:Development Health-related Quality Life COVID-19 patients compared healthy...

10.1093/ofid/ofae631.2093 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Zusammenfassung Für das vorherrschende Symptom Fatigue im Rahmen des Post-COVID-Syndroms (PCS) existieren weiterhin nur eingeschränkte Behandlungsstrategien. Hydrotherapeutische Verfahren zeigten bei anderen Ursachen der positive Effekte. Das primäre Ziel ist es erstmals objektivierbare Daten mittels HRV zur Wirksamkeit von Kniegüssen nach Kneipp auf die Fatique Post-COVID zu generieren. Personen mit relevanter Fatigue, gemessen Chalder Skala, wurden in Studie eingeschlossen. Die...

10.1055/a-2507-0807 article DE Physikalische Medizin Rehabilitationsmedizin Kurortmedizin 2025-01-31

Zusammenfassung Mit dem Rückgang der Letalität von Schwerverletzten haben sich die wissenschaftliche Fragestellung und Sichtweise in klinischen Praxis Richtung qualitativer Ergebnisparameter verändert. Langzeiterhebung des patientenberichteten Outcomes soll Argumentation für eine strukturierte Nachsorge lückenlose Traumarehabilitation unterstützt werden. Patienten sollen zehn Jahre nach einer schweren Verletzung mit einem Injury Severity Score mind. 16 Punkten mithilfe...

10.1055/a-2505-5248 article DE Die Rehabilitation 2025-03-03

Abstract Purpose Steatotic liver diseases (SLD) have become more prevalent over the last decade and are associated not only with cardiometabolic but also psychological symptoms (depression, fatigue). These common in post-COVID syndrome (PCS). Therefore, aim of study was to analyze burden SLD PCS patients. Methods We systematically screened all patients from our outpatient clinic using transient elastography, structured questionnaires for neurocognitive evaluation blood sample analysis....

10.1007/s15010-025-02531-x article EN cc-by Infection 2025-04-10

Zusammenfassung Hintergrund Das Beschwerdebild der Folgeerscheinungen, die nach einer COVID-19-Erkrankung auch Monaten existieren können, wird immer deutlicher: das Post-COVID-Syndrom. Neben verschiedenen Symptomen können funktionellen Zusammenhänge bestehen, Arbeitsfähigkeit einschränken. Derzeitige Untersuchungen gehen von 10% Infizierten aus, dies betrifft. In Deutschland würde aktuellen Zahlen 380 000 Menschen betreffen. Ziel dieser Analyse war es zu zeigen, wie sich reale und gefühlte...

10.1055/a-1674-8044 article DE Physikalische Medizin Rehabilitationsmedizin Kurortmedizin 2021-11-15

A relevant proportion of patients suffer from long-lasting impairments following an acute SARS-CoV-2 infection. The proposed post-COVID syndrome (PCS) score may improve comparison in the course and classification affected patients. prospective cohort 952 presenting to outpatient clinic at Jena University Hospital, Germany, was enrolled. Patients received a structured examination. PCS calculated per visit. total 378 (39.7%) 129 (13.6%) entire population visited two or three times,...

10.3390/jcm12124013 article EN Journal of Clinical Medicine 2023-06-12

Abstract There is a lack of interventions that treat the Post-Covid-19 Condition (PCC) itself. Accordingly, treatment guidelines recommend physiotherapy to alleviate symptoms and enhance functioning. In cases where unimodal treatments prove ineffective, non-organ-specific multidisciplinary bio-psycho-social rehabilitation (MBR) programs are suitable option. pilot observational study with assessments at entry end we aimed evaluate feasibility 3-week day clinic MBR program explore its effects...

10.1007/s00406-023-01747-y article EN cc-by European Archives of Psychiatry and Clinical Neuroscience 2024-01-17

Abstract Study design Cross-sectional explorative observational study. Objectives To identify factors which have an association to the self-perceived Quality of Life (QoL) for persons with acquired spinal cord injury (SCI). Setting Eight specialized SCI-centers in Germany. The GerSCI survey is German part International Spinal Cord Injury Survey (InSCI). Methods Self-disclosure questionnaire, created from InSCI group, translated and adapted questionnaire collects a very broad range data and,...

10.1038/s41393-021-00663-z article EN cc-by Spinal Cord 2021-07-08

Zusammenfassung Die Prävalenz des Post-COVID-Syndroms (PCS) ist noch nicht abschließend geklärt. bisherigen Definitionen bilden vorrangig zeitliche Aspekte ab, lassen jedoch funktionelle Defizite sowie die Objektivierung von Symptomen außer Acht. Dies führt zu diagnostischen therapeutischen Unklarheiten. In Pubmed wurde daher nach systematischen Reviews gesucht, sich mit den Folgen einer SARS-CoV-2-Infektion befassten. zugrunde liegenden zeitlichen Einschlusskriterien wurden extrahiert. 16...

10.1055/a-1940-1222 article DE DMW - Deutsche Medizinische Wochenschrift 2022-10-01
Yanyan Shi Ralf Strobl Christian Apfelbacher Thomas Bahmer Ramsia Geisler and 95 more Peter U. Heuschmann Anna Horn Hanno Hoven Thomas Keil Michael Krawczak Lilian Krist Christina Lemhöfer Wolfgang Lieb Bettina Lorenz‐Depiereux Rafael Mikolajczyk Felipe A. Montellano Jens Peter Reese Stefan Schreiber Nicole Skoetz Stefan Störk Jörg Janne Vehreschild Martin Witzenrath Eva Grill Maria J. G. T. Vehreschild Jörg Janne Vehreschild Hiwa Dashti Barbara Laumerich Oliver Pociuli Nikolaus Büchner Sabine Adler Mathias Lehmann Selçuk Tasci Maximilian Jorczyk T. Keller Michael Schroth Martin Hower Lukas Eberwein Tim Zimmermann Simon-Dominik Herkenrath Milena Milovanovic Ramona Pauli Jörg Simon Eckard Hamelmann Christoph Stellbrink Johannes-Josef Tebbe Sven Stieglitz Christoph Wyen Jan Bosch Mirko Steinmüller Christoph Allerlei Markus Böbel Elke Natascha Heinitz Ariane Roecken Andrea Münckle-Krimly Christiane Guderian Ingmar Silberbaur H. Schäfer Claudia Raichle Christoph D. Spinner Bernd Schmeck Heidi Altmann Nicole Toepfner Wolfgang Schmidt Björn‐Erik Ole Jensen Andreas E. Kremer Sabine Blaschke Jochen Dutzmann Marylyn M. Addo Robert Bals Sven Bercker Phil‐Robin Tepasse Sandra Frank Dirk Müller‐Wieland Anette Friedrichs Jan Rupp Siri Göpel Jens Maschmann Christine Dhillon Jacob Nattermann Ingo Voigt Wilfred Obst Martin F. Sprinzl Christian Scheer Andreas Teufel Ulf Günther Martin Witzenrath Thomas Keil Thomas Zöller Sein Schmidt Michael Hummel Lilian Krist Julia Fricke Maria Rönnefarth Denise Treue Ludie Kretzler Chantip Dang‐Heine Paul Triller Andreas Jooß Jenny Schlesinger Natalja Liseweski

We aimed to assess symptoms in patients after SARS-CoV-2 infection and identify factors predicting prolonged time symptom-free.COVIDOM/NAPKON-POP is a population-based prospective cohort of adults whose first on-site visits were scheduled ≥ 6 months positive PCR test. Retrospective data including self-reported symptom-free collected during the survey before site visit. In survival analyses, being served as event be variable. Data visualized with Kaplan-Meier curves, differences tested...

10.1007/s15010-023-02043-6 article EN cc-by Infection 2023-05-25

Persistent and new-onset symptoms after SARS-CoV-2 infection (so-called Long/Post-COVID syndrome) represent a major challenge for our healthcare system. However, there have been limited data on primary outpatient care planning, complicating patient flow management ultimately care. Assessing the reality of patients with Long/Post-COVID-symptoms, as well their difficulties desires in receiving medical care, is necessary first step toward improving

10.1055/a-2035-9431 article EN Das Gesundheitswesen 2023-05-04

After infection with SARS-CoV-2, a substantial proportion of patients develop long-lasting sequelae. These sequelae include fatigue (potentially as severe that seen in ME/CFS cases), cognitive dysfunction, and psychiatric symptoms. Because the pathophysiology these remains unclear, existing therapeutic concepts address symptoms through pacing strategies, training, psychological therapy.

10.1177/20552076241291748 article EN cc-by-nc-nd Digital Health 2024-01-01

Post-COVID syndrome is affecting many organ systems and arises as a major public health problem with millions of cases worldwide. The primary aim this study the analysis problems, activity limitations participation restrictions (ALPR) participants post-COVID symptoms investigation correlations between these elements to derive statements about rehabilitation need, also depending on sex. A retrospective cohort was performed collect longitudinal data from January 2022 2023 using Covid-19...

10.1038/s41598-024-74568-1 article EN cc-by Scientific Reports 2024-10-17

Zusammenfassung Hintergrund Der Anspruch von Patienten an Knietotalprothesen (KTEP) wächst zunehmend. Es stellt sich immer wieder die Frage, ob sportlich aktive nach Implantation einer KTEP ein erhöhtes Revisionsrisiko aufweisen im Vergleich zu ohne sportliche Aktivitäten. Patienten/Material und Methoden In retrospektiven Studie wurden 130 mit einem Altersdurchschnitt 69,2 Jahren Ihrer sportlichen Aktivität 22 Monate vor Primärimplantation befragt. Die aufgrund der Ergebnisse Befragung in 2...

10.1055/s-0043-103007 article DE Sportverletzung · Sportschaden 2017-06-01

Zusammenfassung Ziel Die Auswirkungen der COVID-19-Pandemie sind wirtschaftlich, global aber auch individuell noch nicht abzu-schätzen. Aufgrund Neuartigkeit wurden in Deutschland viele ad-hoc-Entscheidungen getroffen, die Einfluss auf das gesamte Gesundheitswesen hatten. Dies betraf sowohl Abläufe Gesundheitsämtern, als direkt medizinische Versorgung COVID-19-Erkrankter, durch multiple Faktoren zum Teil keine adäquate ambulante Therapie erhielten. Das Untersuchung war es, Zufriedenheit von...

10.1055/a-1528-1667 article DE Physikalische Medizin Rehabilitationsmedizin Kurortmedizin 2021-08-25
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