A5028589921- Shoulder Injury and Treatment
- Total Knee Arthroplasty Outcomes
- Remote Sensing in Agriculture
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Trauma Management and Diagnosis
- Remote Sensing and LiDAR Applications
- Orthopedic Surgery and Rehabilitation
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Land Use and Ecosystem Services
- HIV Research and Treatment
- Elbow and Forearm Trauma Treatment
- Tendon Structure and Treatment
- Satellite Image Processing and Photogrammetry
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- Cerebrovascular and Carotid Artery Diseases
- Forest Management and Policy
- Rangeland and Wildlife Management
- Pelvic and Acetabular Injuries
- Osteoarthritis Treatment and Mechanisms
- Sports injuries and prevention
- Space exploration and regulation
- Leaf Properties and Growth Measurement
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2009-2023
University of Tübingen
2013-2017
BG Klinik Tübingen
2013-2017
Icahn School of Medicine at Mount Sinai
2014-2017
Klinikum rechts der Isar
2009-2016
LMU Klinikum
2012
Technical University of Munich
2009-2012
Friedrich-Alexander-Universität Erlangen-Nürnberg
1997-2007
Max Planck Institute of Psychiatry
2006
Mount Sinai Medical Center
1996
The influence of stem cells and lentiviral expression basic fibroblastic growth factor (bFGF) on tendon healing remodelling was investigated in an in-vivo long-term (12 weeks) rat Achilles defect model. In sixty male Lewis rats, complete defects (2.4 mm) were created either left untreated (PBS) or treated by injection lentivirally expressing the enhanced green fluorescence marker gene eGFP (MSC-LV-eGFP) fibroblast bFGF (MSC-LV-bFGF). Tendons harvested after 12 weeks underwent biomechanical...
Abstract Purpose The objective examination of the Post-COVID syndrome (PCS) remains difficult due to heterogeneous definitions and clinical phenotypes. aim study was verify functionality correlates a recently developed PCS score. Methods score applied prospective, multi-center cross-sectoral cohort (in- outpatients with SARS-CoV-2 infection) "National Pandemic Cohort Network (NAPKON, Germany)". Symptom assessment patient-reported outcome measure questionnaires were analyzed at 3 12 months...
We investigated cytokine production and accessory cell function in human macrophage hybridoma lines primary monocytes after infection with HIV-1. HIV-1 induced IL-10 the line loss of IL-12 1 wk infection. There were also significant increases (537 +/- 521 vs 687 625 pg/ml) while there was a reduction (6.3 3.1 1.2 1.0 pg/ml, p = 0.021) 5 days In addition, failed to support PHA, Con A, PWM, or anti-CD3- T proliferation The viability cells cocultured HIV-1-infected as determined by propidium...
The recent identification of coreceptors that mediate efficient entry human immunodeficiency virus type 1 (HIV-1) suggests new therapeutic and preventive strategies. We analyzed simian (SIV) cofactors to investigate whether the macaque SIV model can be used as an experimental evaluate these Similar primary HIV-1 isolates, a well-characterized molecular clone, SIVmac239, which replicates poorly but efficiently enters into rhesus alveolar macrophages envelope variant, SIVmac239/316Env, with...
Background: The aim of this controlled study was to investigate the influence mesenchymal stem cells (MSCs) and lentiviral (LV) expression basic fibroblast growth factor (bFGF) on tendon remodeling in an vivo rat model Achilles defect. Methods: In eighty-four male Lewis rats, complete 2.4-mm defects were created either left untreated (the phosphate-buffered saline solution [PBS] group) or treated with expressing enhanced green fluorescent protein MSC-LV-eGFP lentivirally MSC-LV-bFGF group)....
On a daily basis, political decisions are made, often with their full extent of impact being unclear. Not seldom, the and policy measures implemented result in direct or indirect unintended negative impacts, such as on natural environment, which can vary time, space, nature, severity. To achieve more sustainable world equitable societies requires fundamental rethinking our policymaking. It calls for informed decision making monitoring evidence-based knowledge is necessary. The most powerful...
Earth Observation satellite data allows for the monitoring of surface our planet at predefined intervals covering large areas. However, there is only one medium resolution sensor family in orbit that enables an observation time span 40 and more years a daily repeat interval. This AVHRR family. If we want to investigate long-term impacts climate change on environment, can do so based remains available several decades. then processes with respect change, need very high temporal enabling...
The disturbance vicariance hypothesis (DV) has been proposed to explain speciation in Amazonia, especially its edge regions, e.g. eastern Guiana Shield harlequin frogs (Atelopus) which are suggested have derived from a cool-adapted Andean ancestor. In concordance with DV predictions we studied that (i) these amphibians display natural distribution gap central Amazonia; (ii) east of this they constitute monophyletic lineage is nested within pre-Andean/western clade; (iii) climate envelopes...
Operational standard products of biophysical variables, such as leaf area index (LAI) derived from satellite observations (e.g. Moderate Resolution Imaging Spectroradiometer (MODIS), Medium Spectrometer (MERIS) or VEGETATION), serve the need for adequate input data quantitative modelling ecosystem dynamics on regional to global scales. For validation those and local applications, higher resolution LAI maps based field high spatial are crucial. As sites in tropical rainforests rare, a study...
INTRODUCTION While plate fixation remains the gold standard for surgical treatment displaced mid-shaft clavicle fractures (DMCF), intramedullary has emerged as a promising alternative. However, due to its more demanding technique and depending on fracture's nature, an open reduction can be necessary. Aim of this study was compare outcome versus closed DMCF using ESIN. PATIENTS AND METHODS Titanium Elastic Nail (TEN) were used treat 40 patients undergoing minimally invasive ESIN between...
Object-based semi-automated segmentation and classification approaches have gained importance in the analysis of remote sensing data over last few years. Particularly when it comes to operational processing multi-seasonal input data, independent robust algorithms are needed. At German Aerospace Center (DLR) a new method for forest type has been developed, covering all steps object-based classification. An automatic adaptation scene-specific feature values is implemented, based on automated...
Recent findings suggest an important role of subtle changes in the plasma levels inflammatory cytokines within brain-immune interplay. It is unclear how such are regulated absence acute or infectious stimuli. Endocrine systems a good candidate, because innate immunity and hypothalamo-pituitary-adrenal (HPA)-system closely related: glucocorticoids have immunosuppressive properties modulate cytokine release from stimulated mononuclear blood cells vitro immune response vivo, but it still...