A5073606932- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Immune Response and Inflammation
- Sympathectomy and Hyperhidrosis Treatments
- Long-Term Effects of COVID-19
- Immune cells in cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disorders and Treatments
- Health Literacy and Information Accessibility
- Neuropeptides and Animal Physiology
- Multiple Sclerosis Research Studies
- Transcranial Magnetic Stimulation Studies
- Hallucinations in medical conditions
- Respiratory and Cough-Related Research
- Thyroid Disorders and Treatments
- Motor Control and Adaptation
- Nicotinic Acetylcholine Receptors Study
- COVID-19 Clinical Research Studies
- Ophthalmology and Eye Disorders
- Body Image and Dysmorphia Studies
- Neuroscience of respiration and sleep
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hemispheric Asymmetry in Neuroscience
- Psychosomatic Disorders and Their Treatments
- COVID-19 and Mental Health
Charité - Universitätsmedizin Berlin
2021-2024
Freie Universität Berlin
2024
Humboldt-Universität zu Berlin
2023-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2023
Max Delbrück Center
2020
Therapeutic options for migraine prevention in non-responders to monoclonal antibodies (mAbs) targeting Calcitonin Gene-Related Peptide (CGRP) and its receptor are often limited. Real-world data have shown that the CGRP-receptor mAb erenumab may benefit from switching a CGRP ligand mAb. However, it remains unclear whether, vice versa, is effective mAbs. In this study, we aim assess efficacy of patients who previously failed mAb.This monocentric retrospective cohort study included with...
Migraine is a disabling neurovascular disorder among people of all ages, with the highest prevalence in fertile years, and women. impacts quality life affected individuals tremendously and, addition, it associated highly prevalent metabolic diseases, such as obesity, diabetes mellitus thyroid dysfunction. Also, clinical response to drugs might be patients disease due body composition change. Therefore, efficacy antimigraine could altered both migraine disease. However, knowledge pharmacology...
Monoclonal antibodies (mAbs) targeting the Calcitonin Gene-Related Peptide (CGRP) pathway are safe and effective treatments for migraine prevention. However, high cost of these novel therapies has led to reimbursement policies requiring patients try multiple traditional preventives before access. In Germany, a recent change in insurance policy significantly expanded coverage CGRP receptor mAb erenumab, enabling who failed just one prior prophylactic medication receive this mAb. Here, we...
Migraine and sleep disorders share a bidirectional relationship, but little is known about the specific association between migraine rapid eye movement (REM) behaviour disorder (RBD). The aim was to assess prevalence of RBD associated clinical characteristics in adults with migraine.
Malignant gliomas are primary brain tumors with poor prognoses. These infiltrated by intrinsic microglia and peripheral monocytes which promote glioma cell invasion. In our previous studies, we discovered that the activation of Toll-like receptor 2 (TLR2) on microglia/brain macrophages converts them into a protumorigenic phenotype through induction matrix metalloproteinases (MMP) 9 14. present study, used in vitro situ microglia-glioma interaction experimental models to test impact novel...
We aimed to assess symptoms in patients after SARS-CoV-2 infection and identify factors predicting prolonged time symptom-free.COVIDOM/NAPKON-POP is a population-based prospective cohort of adults whose first on-site visits were scheduled ≥ 6 months positive PCR test. Retrospective data including self-reported symptom-free collected during the survey before site visit. In survival analyses, being served as event be variable. Data visualized with Kaplan-Meier curves, differences tested...
Abstract Objective Alice in Wonderland Syndrome (AIWS) is a sensory disorder characterized by distorted somatosensory and/or visual perception. Additionally, distortion of time perception and symptoms derealization/depersonalization may occur. AIWS frequently associated with migraine. However, its prevalence, clinical characteristics remain poorly understood. Here, we investigated the prevalence features individuals We hypothesized more frequent migraine patients aura than those without...
Background Migraine patients unresponsive to calcitonin gene-related peptide (CGRP)(-receptor, -R) monoclonal antibodies (mAbs) may benefit from switching between CGRP(-R) mAbs. However, some do not tolerate or respond any subcutaneous This study evaluates the efficacy of intravenous CGRP mAb eptinezumab in these therapy-refractory patients. Methods In this retrospective cohort study, with migraine who previously failed erenumab and at least one (fremanezumab and/or galcanezumab) received...
Migraine aura, near-death experiences (NDEs), and rapid eye movement (REM) sleep intrusions might share common mechanisms. Here, we investigated the prevalence of NDEs REM in people with migraine. We hypothesized that are more prevalent migraine patients aura than those without.We conducted a prospective cross-sectional cohort study at tertiary headache center, based on prespecified sample size (n = 808). completed series questionnaires, including questions about demographic characteristics,...
Abstract Background The severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) pandemic causes a high burden of and long-term morbidity mortality worldwide despite global efforts in containment, prophylaxis, therapy. With unprecedented speed, the scientific community has generated pivotal insights into pathogen host response evoked by infection. However, deeper characterization pathophysiology pathology remains priority to reduce coronavirus disease 2019 (COVID-19). Methods NAPKON-HAP...
The medial portrayal of migraine is often stereotypical and inaccurate but reflects how society perceives migraine. discrepancy between others' views the reality affected individuals may negatively affect access to treatment disease course patients with This study aimed investigate whether images presented in media as typical attacks are perceived realistic representative by Rostock, a smaller town rural Germany, compare results those from Berlin, large metropolis. We performed an online...
Objectives: The significance of pre-motor (PMC) corticospinal projections in a frontoparietal motor network remains elusive. Temporal activation patterns can provide valuable information about region's engagement hierarchical network. Navigated transcranial magnetic stimulation (nTMS)-induced virtual lesions an excellent method to study cortical physiology by disrupting ongoing activity at high temporal resolution and anatomical precision. We use nTMS-induced applied during established...