A5042233543- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- Molecular Junctions and Nanostructures
- Chemical Reactions and Isotopes
- Photodynamic Therapy Research Studies
- Bone health and osteoporosis research
- Biosensors and Analytical Detection
- Orthopaedic implants and arthroplasty
- Analytical Chemistry and Sensors
- Cancer, Hypoxia, and Metabolism
- Light effects on plants
- Advanced Chemical Sensor Technologies
- Electrochemical sensors and biosensors
- Plant Genetic and Mutation Studies
- Bone Tissue Engineering Materials
- Plant Molecular Biology Research
- Gold and Silver Nanoparticles Synthesis and Applications
Institute of Environmental Science and Research
2025
MacDiarmid Institute for Advanced Materials and Nanotechnology
2025
Victoria University of Wellington
2025
The University of Texas Health Science Center at San Antonio
2007
Lanzhou University
2004
University of Arkansas at Little Rock
1993
Electrochemical aptamer-based biosensors (E-aptasensors) are emerging platforms for point-of-care (POC) detection of complex biofluids. Human saliva particularly offers a noninvasive matrix and unprecedented convenience detecting illicit drugs, such as cocaine. However, the sensitivity cocaine E-aptasensors is significantly compromised in saliva. Herein, we investigated influence salivary components on sensing performance methylene blue (MB)-labeled classic aptamer by square-wave voltammetry...
DNA intercalating cyanine dyes, such as SYBR Green I (SG) and OliGreen (OG), are widely used in developing label-free, fluorescent aptamer-based biosensors. Despite their widespread use for direct analyte detection through changes fluorescence intensity, the effects of dye concentrations specific nature interactions have been inadequately explored. Here, we reported how dye-to-base ratios (dbrs) influence response dyes aptamer systems targeting adenosine triphosphate (ATP) l-argininamide...
Despite the rapid growth in aptamer-based biosensor research, there remains a significant demand for aptasensors that operate without need sample preparation and calibration, to better facilitate real-world applications. Electrochemical (EAB) sensors, particularly those utilizing dual-frequency, calibration-free approach, have shown promising advances toward commercialization. Single-use, disposable sensors represent cost-effective solution at-home on-site point-of-care (POC) diagnostics....
Thiolated DNA biopolymer probes are widely used for their spontaneous interactions with gold electrodes to achieve self-assembled monolayers (SAMs) of DNA. This offers an attractive class bio-interfaces developing point-of-care (POC) diagnostics. However, SAMs prone structural instability and can be challenging reproducibly fabricate different sizes shapes. Among methods studying SAMs, electrochemical impedance spectroscopy (EIS) has attracted a lot attention its extremely high sensitivity...
Abstract Osteoblasts are exposed to fluid shear in vivo but the effects not well understood, particularly how substrate properties or length of exposure modify response. Short (1 h) reduces stimulatory effect micron‐scale surface structure on osteoblast differentiation, longer term exposures known. To test hypothesis that substrate‐dependent responses osteoblasts depend flow, MG63 were grown tissue culture glass, which has an average roughness (Ra) < 0.2 μm; machined Ti disks (PT, Ra 0.6...
Photodynamic therapy (PDT) has emerged as a promising modality for the treatment of cancer. We are using newly synthesized and chemically defined characterized porphyrin photosensitizers that specifically labeled with deuterium to perform in vivo NMR studies murine tumor model. In magnetic resonance offers potential repetitive, safe, noninvasive evaluation photosensitizers, metabolism, effect PDT on metabolism. an effort monitor noninvasively model, we synthesizing several which absorb red...