A5065885778- Migraine and Headache Studies
- Epilepsy research and treatment
- Ophthalmology and Eye Disorders
- Pharmacological Effects and Toxicity Studies
- Blood properties and coagulation
- Sympathectomy and Hyperhidrosis Treatments
- Erythrocyte Function and Pathophysiology
- Craniofacial Disorders and Treatments
- Neurological Complications and Syndromes
- Genetics and Neurodevelopmental Disorders
- Glycogen Storage Diseases and Myoclonus
- Neuroscience of respiration and sleep
- Trigeminal Neuralgia and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Neurological and metabolic disorders
- Human Health and Disease
- Genetic Syndromes and Imprinting
- Folate and B Vitamins Research
- Anesthesia and Neurotoxicity Research
- Long-Term Effects of COVID-19
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Moyamoya disease diagnosis and treatment
- Thyroid Disorders and Treatments
- Neonatal Health and Biochemistry
University of L'Aquila
2013-2024
San Salvatore Hospital
2009-2022
University of Padua
2015
Background and purpose Increased headache frequency severity have been observed in obese populations, but the real impact of a weight loss treatment on has not studied. We investigated this issue sample adolescents. Methods In all, 135 migraineurs, aged 14–18 years, with body mass index ( BMI ) ≥97th percentile, participating 12‐month‐long program, were studied before after treatment. The program included dietary education, specific physical training, behavioral Results Decreases P <...
Objective The present Italian multicenter study aimed at investigating whether the course of primary headache disorders in children and adolescents was changed during lockdown necessary to contain COVID-19 emergency Italy. Methods During lockdown, we submitted an online questionnaire patients already diagnosed with disorders. Questions explored headache, daily habits, psychological factors related COVID-19, general mood school stress. Answers were transformed into data for statistical...
The aim of this study was to evaluate the efficacy and tolerability levetiracetam (LEV) monotherapy in juvenile myoclonic epilepsy (JME). group consisted 32 patients with (20 males, 12 females) a mean age 13 years 3 months (SD 7y 11mo) at seizure onset. LEV administered as first drug; all were followed up 6 months. dose that achieved control ranged from 1000 2500mg/daily. At 6‐month evaluation: 15 free; 14 responders (>50% reduction seizures); three had marginal effects (<50%...
This paper reports on the clinical aspects, electroencephalographic (EEG) features, and neuroimaging findings in children with full trisomy 18 associated epilepsy, compares evolution outcome of their neurological phenotype. We retrospectively studied patients (10 males 8 females; aged 14 months to 9 years) epilepsy. All underwent comprehensive assessment including studies brain. divided into two groups according findings: (Group 1) 10 harboring structural brain malformations, 2) normal...
Aims: This study was planned to investigate the diagnostic utility of osmophobia as criterion for migraine without aura (MO) proposed in Appendix (A1.1) International Classification Headache Disorders (ICHD-II, 2004). Methods: We analysed 1020 patients presenting at 10 Italian juvenile headache centres, 622 affected by (M) and 328 tension-type (TTH); 70 were not elsewhere classified (NEC) ICHD-II. By using a semi-structured questionnaire, prevalence 26.9%, significantly higher M than TTH...
Background: Osmophobia is frequent in children with migraine (20–35%) but can also occur up to 14% of cases tension-type headache (TTH). So far, the prognostic role this symptom primary headaches has never been evaluated. Methods: A longitudinal prospective study was conducted on 90 young patients TTH (37 osmophobia, 53 without osmophobia). We evaluated whether osmophobia could predict diagnosis transformation from after a 3-year follow-up. Results and Discussion: In our rate change...
Weight loss can determine significant improvement of migraine in obese patients. Herein, we evaluated a clinical sample adolescent migraineurs with obesity who participated an interdisciplinary programme for weight loss, order to identify possible metabolic parameters associated good control.Using cross-sectional design, 112 out 135 adolescents previously underwent our intervention programme. Based on persistence headache, subjects comparison were 40 migraine-free and 72 not adolescents....
The Appraisal of Guidelines for Research and Evaluation (AGREE II) tool is a validated questionnaire used to assess the methodological quality clinical guidelines (CGs). We AGREE II development process, quality, reporting available pediatric CGs management headache in children. also studied variability responses related characteristics eleven Italian neuropediatric centers, showing similarities differences main recommendations reported CGs. A systematic literature search was conducted from...
Background: Data on clinical presentation of Hemiplegic Migraine (HM) are quite limited in the literature, particularly pediatric age. The aim present study is to describe detail phenotypic features at onset and during first years disease sporadic (SHM) familial (FHM) hemiplegic migraine review pertinent literature. Results: Retrospective a cohort children adolescents diagnosed with migraine, recruited from 11 Italian specialized Juvenile Headache Centers. Forty-six cases (24 females) were...
Background: The purpose of this review is to clarify the natural course Benign Paroxysmal Torticollis (BPT) and update relationship disorder with migraine. BPT belongs a group “episodic syndromes that may be associated migraine” diagnosed when according diagnostic criteria International Classification Headache Disorders, 3rd edition. It present in infants young children it an underdiagnosed manifestation, because not well recognized most cases benign evolution, but requires careful...
Changes in visual evoked potentials and decreased intracellular magnesium levels have been separately described patients affected by migraine both during the attacks interictal periods. An inverse correlation between increased P100 amplitude lowered serum was found children suffering from with without aura a headache‐free period. A 20‐day treatment oral pidolate seemed to normalize balance 90% of patients. After treatment, reduced confirmed level. These data seem suggest hypothesis that...
Background and purposes To determine the prevalence of SLC 2A1 mutations in children with early‐onset absence epilepsy ( EOAE ) to investigate whether there were differences demographic electroclinical data between patients who became seizure‐free anti‐epileptic drug AED monotherapy (group I) those needed add‐on treatment a second II ). Methods We reviewed attending different Italian centers. All participants had onset seizures within first 3 years life but otherwise conformed strict...
Primary headaches (H) and learning disabilities (LD) are frequent in childhood can coexist the same subject, but their correlation is not always clear. The aim of our study was to evaluate this relationship considering also any psychopathologies influence on quality life by an aspect such as school absences.One hundred ninety-three children (8-18y) with H LD assessed consecutively at Headache Center L'Aquila, from 2013 2018 sample. School problems were evaluated Italian batteries for LD;...
The aim of this open label pilot study was to evaluate the efficacy and tolerability levetiracetam (LEV) as 'de novo' monotherapy in children adolescents with late onset childhood occipital epilepsy-Gastaut type (COE-G).Twelve patients suffering from COE-G were enrolled prospective study. age seizures ranged 6.1 16.2 years a peak frequency at mean (+/-SD) 10.54 +/- 2.77 years. Therapy LEV started 10 mg/kg/day and, after titration, final dose generally achieved within 4 weeks 20.7 45.2...
Summary Purpose To investigate whether patients with typical absence seizures ( TAS ) starting in the first 3 years of life, conformed to Panayiotopoulos's definition childhood epilepsy CAE ), show different electroclinical course than those not fulfilling criteria. Methods In this multicenter retrospective study, we choose a fixed duration follow‐up 36 months examine all children before age. The probands who fulfilled criteria for were classified as having pure early onset (P‐ EOAE whereas...