A5039978500- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Infant Nutrition and Health
- Antimicrobial Peptides and Activities
- Virus-based gene therapy research
- Animal Virus Infections Studies
- Pharmacological Effects of Medicinal Plants
- Animal Nutrition and Physiology
- T-cell and B-cell Immunology
- Viral gastroenteritis research and epidemiology
- Inflammatory Bowel Disease
- Congenital Diaphragmatic Hernia Studies
- Immune Cell Function and Interaction
- Garlic and Onion Studies
- Neonatal Respiratory Health Research
- Probiotics and Fermented Foods
Tianjin Medical University
2025
Nanjing Medical University
2021
Nanjing Agricultural University
2017-2019
Pig diarrhea causes high mortality and large economic losses in the swine industry. Transmissible gastroenteritis virus (TGEV) pig diarrhea, with 100% piglets less than 2 weeks old. No investigation has yet been made of small intestine that survived infection by TGEV. In this study, we evaluated impact TGEV on recovered pigs. Histological analyses showed led to villi atrophy, reduced villous height crypt depth. The number SIgA positive cells, CD3+T dendritic cells (DCs) jejunum decreased...
Inflammatory bowel disease (IBD) is a chronically relapsing inflammatory disorder of the gastrointestinal tract. Current IBD treatments have poor tolerability and insufficient therapeutic efficacy, thus, alternative approaches are required. Recently, number dietary supplements emerged as promising interventions. In present study oral administration carotenoid (4,4'-diaponeurosporene)-producing Bacillus subtilis markedly ameliorated dextran sulfate sodium salt-induced mouse colitis,...
The nasal mucosa is the body's first barrier against pathogens entering through respiratory tract. immune system of pigs has more similarities with humans than mouse does, and so was selected as animal model in present study. To evaluate effects Bacillus subtilis a potential probiotic to stimulate local responses, piglets were intranasally administered Dylight 488‑labeled B. (WB800‑green fluorescent protein). results revealed that able reach lamina propria mucosa, nasopharyngeal tonsils soft...
Gut mucosal immune responses are known to act as the first line of defense against invasion pathogenic microorganisms. Piglets have an incompletely developed gut system, making them sensitive intestinal infections. Promoting development system will increase pathogen resistance piglets. The aim present study was investigate effect carotenoid (4,4'-diaponeurosporene)-producing Bacillus subtilis (B.s-Dia) on immunity in We showed that oral administration piglets B.s-Dia remarkably improved...
As an immune privilege site, there are various types of cells in the testis. Previous research has been focused on testicular macrophages, and much less is known about T Here, we found that with memory phenotypes were most abundant leukocyte testis except for macrophages. Our results showed proportion increases gradually from birth to adulthood mice primary type changed γδTCR+ αβTCR+ cells. In addition, under homeostatic conditions, CD8+ dominant subgroup have different phenotypic...
Abstract Tonsils form the topographically first immune barrier of an organism against invasion pathogens. We used histology to study development tonsils pigs after birth. At birth, consist diffuse lymphoid tissue without any follicle aggregations. age 7 days, follicles appeared in soft palate tonsil. The layer nasopharyngeal tonsil, and lingual tonsil became thicker, lamina propria were clearly visible at 21 days. Secondary present 50 120 Dendritic cells (DCs), CD3 + T IgA B increased...