A5059859639- Synthesis and biological activity
- Cholinesterase and Neurodegenerative Diseases
- Nanocluster Synthesis and Applications
- X-ray Diffraction in Crystallography
- HIV/AIDS drug development and treatment
- Advanced Nanomaterials in Catalysis
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- Biochemical and Molecular Research
- Molecular Sensors and Ion Detection
- Computational Drug Discovery Methods
- Polymer Synthesis and Characterization
- Electrochemical sensors and biosensors
Guangxi Science and Technology Department
2024
Guangxi Medical University
2021
In this study, two “on–off” probes (BF2-cur-Ben and BF2-cur-But) recognizing acetylcholinesterase (AChE) were designed synthesized. The obtained can achieve recognition of AChE with good selectivity pH-independence a linear range 0.5~7 U/mL 0.5~25 respectively. BF2-cur-Ben has lower limit detection (LOD) (0.031 U/mL), higher enzyme affinity (Km = 16 ± 1.6 μM), inhibitor sensitivity. A responsive mechanism the for was proposed based on HPLC mass spectra (MS) experiments, as well calculations....
X-ray powder diffraction data, unit-cell parameters, and space group for N , -dimethyl-1H-benzo[d]imidazol-2-amine, C 9 H 11 3 are reported [ a = 11.379(3) Å, b 10.227(5) c 7.151(1) α 90°, β γ volume V 832.318 Å Z 4, ρ cal 1.286 g cm −3 P 2 1 2]. All measured lines were indexed consistent with the group. No detectable impurities observed.