A5101627813- Venous Thromboembolism Diagnosis and Management
- Hepatitis C virus research
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- HIV/AIDS drug development and treatment
- Organ Transplantation Techniques and Outcomes
- Pancreatitis Pathology and Treatment
- HIV, Drug Use, Sexual Risk
- Malaria Research and Control
- HIV Research and Treatment
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Nerve injury and regeneration
- Pain Mechanisms and Treatments
- Colorectal Cancer Surgical Treatments
- Misinformation and Its Impacts
- Hepatitis Viruses Studies and Epidemiology
- Virology and Viral Diseases
- HIV-related health complications and treatments
- Pancreatic and Hepatic Oncology Research
- Epilepsy research and treatment
- stochastic dynamics and bifurcation
- Mesenchymal stem cell research
- Drug-Induced Hepatotoxicity and Protection
Peking University First Hospital
2024-2025
Peking University
2024-2025
Xuzhou Medical College
2024
Obstetrics and Gynecology Hospital of Fudan University
2024
Henan Provincial Center for Disease Control and Prevention
2016-2024
Hangzhou First People's Hospital
2023
Zhejiang University
2023
Second Hospital of Tangshan
2023
Beijing University of Posts and Telecommunications
2021-2022
Beijing YouAn Hospital
2011-2022
Mesenchymal stem cells (MSCs) may influence the growth and metastasis of various human malignancies, including hepatocellular carcinoma (HCC). Therefore, underlying mechanisms via which MSCs are able to affect malignancies require investigation. In present study, potential role MSC in angiogenesis HCC was investigated. A total 17 nude mouse models exhibiting were used evaluate effects on angiogenesis. 8 mice injected with tail vein, remaining 9 phosphate-buffered saline as a control. 35 days...
Background: Lopinavir/ritonavir (LPV/r) is a major antiretroviral treatment in China, but little known about the performance of first-line LPV/r-based regimens treatment-naïve patients with HIV-1. This study aims to assess efficacy and adverse effect events LPV/r plus lamivudine tenofovir or zidovudine as an initial HIV-1-infected individuals for whom cannot take efavirenz (EFV) allergic EFV. Methods: We performed retrospective registering China's National Free Antiretroviral Treatment...
Abstract As two groups of bases in fibers, cylindrical vector (CV) modes and the orbital angular momentum (OAM) can be transformed into each other. Several transformation relations have been studied previous works, such as <m:math xmlns:m="http://www.w3.org/1998/Math/MathML"> <m:mrow> <m:msup> <m:mover> <m:mi>σ</m:mi> <m:mo>^</m:mo> </m:mover> <m:mo>+</m:mo> </m:msup> <m:mi>O</m:mi> <m:mi>A</m:mi> <m:msub> <m:mi>M</m:mi> <m:mi>l</m:mi> </m:mrow> </m:msub> <m:mo>=</m:mo> <m:mi>H</m:mi>...
Abstract We conducted a prospective cohort study among HIV-negative MSM aged 18 years or older between 2007 and 2012 in Beijing, China to measure the rates of incident HIV identify risk factors for infection. Among 5,800 participants evaluated at enrollment, we identified 486 prevalent cases (8.4%). 3,625 enrollees who were enrollment completed least one follow-up interview, 440 follow up period: this constituted an incidence rate 7.1 per 100 person-years (95% CI: 6.4–7.7). Early treatment...
Anti-malarial drug resistance is a primary public health problem. Haplotypes of pfcrt gene have been implicated to be molecular markers chloroquine (CQ) resistance. This study aims explore the prevalence polymorphisms in Plasmodium falciparum-infected patients imported from Africa Henan province.Blood samples were collected 502 who infected with P. falciparum returning province during 2012-2015. The single nucleotide (codons 72-76) assessed by nested PCR DNA sequencing and restriction...
Objective The study aimed to investigate the combined effects of structured exercise therapy and a low glycaemic diet on quality life psychosocial functions in children with epilepsy. Methods Forty-two subjects aged 11 17 years diagnosed refractory epilepsy were recruited. Structured home-based designed by specialists administered for 6 months. Children’s Depression Inventory (CDI) Quality Life Childhood Epilepsy Questionnaire (QOLCE-55) administrated compare treatment after Results...
Objective To evaluate the correlation of total lymphocyte count (TLC) and CD4 cell suitability TLC as a surrogate marker for HIV-infected patients in China. Methods Usefulness <350 cells/mm3 HIV-positive China was evaluated by 977 pairs from outpatients. The result then validated literature review which conducted on 9 relevant articles. Further investigation using data done to determine threshold predicting <500 cells/mm3. Correlation receiver operating characteristic (ROC) analysis were...
Hepatitis B surface antigen (HBsAg) clearance is the closest cure outcome in hepatitis B. The goal of this study was to investigate clinical features chronic patients achieving seroconversion HBsAg after treatment with α-interferon (IFN-α) and a nucleos(t)ide analog.This retrospective enrolled 38 treated IFN-α plus analog who achieved during period from June 2001 May 2009. Clinical laboratory data were collected before every 3 months. All followed up for at least 12 months post-treatment.A...
Background Gastrointestinal bleeding (GIB) is a common condition in clinical practice, and predictive models for patients with GIB have been developed. However, assessments of in-hospital mortality due to the intensive care unit (ICU), especially critically ill patients, are still lacking. This study was designed screen out independent factors affecting thus establish model use. Methods retrospective included 1,442 who had admitted ICU. They were selected from Medical Information Mart...
A flashing ratchet model of a two-headed molecular motor in two-dimensional potential is proposed to simulate the hand-over-hand motion kinesins. Extensive Langevin simulations are performed. We discuss dependences and efficiency on parameters, including external force temperature. good qualitative agreement with expected behavior observed.
Abstract Background Although the global human immunodeficiency virus (HIV) epidemic has improved significantly due to antiretroviral treatment (ART), ART-related adverse events (AEs) remain an issue. Therefore, investigating factors associated with AEs may provide vital information for monitoring risks. Methods A prospective cohort study was conducted among adult patients (aged 18 years or older) HIV who received Tenofovir (TDF) + Lamivudine (3TC) Efavirenz (EFV) as first-line ART regimens....
Single-tablet regimen (STR) provides a convenient once-daily for the prevention of human immunodeficiency virus (HIV) infection. Here, we investigated safety and tolerability coformulated bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as three-drug, STR post-exposure prophylaxis (PEP) in Chinese individuals.
Health support has been sought by the public from online social media after outbreak of novel coronavirus disease 2019 (COVID-19). In addition to physical symptoms caused virus, there are adverse impacts on psychological responses. Therefore, precisely capturing emotions becomes crucial providing adequate support. By constructing a domain-specific COVID-19 health emergency discrete emotion lexicon, we utilized one million theme texts Chinese platform Weibo analyze social-emotional...
(1) Background: Understanding vascular patterns is crucial for minimizing bleeding and operating time in colorectal surgeries. This study aimed to develop an anatomical atlas of the inferior mesenteric artery (IMA) vein (IMV). (2) Methods: A total 521 patients with left-sided cancer were included. IMA IMV identified using maximum-intensity projection (MIP) three-dimensional (3D) reconstruction techniques. The accuracy these techniques was assessed by comparing them surgical videos. We...
Abstract To investigate the different expression of epidermal growth factor receptor 1 (EGFR) and human 2 (HER2) in gastric cancer based on tumor locations its impact patients survival. Gastric is heterogeneous disease, recent years have established a molecular classification described distribution subtypes stomach. However, difference EGFR HER-2 among location still unknown. Between January 2010 August 2014, 2477 consecutive with were treated our surgery department. The classified into 4...
Cholangiography is an important method for the diagnosis of biliary complications after orthotopic liver transplantation. The cholangiography transplantation presents special challenges, especially in patients with cast/stone and stenosis. We described T-tube combined therapeutic fibro-choledochoscopy treatment cast following Fourteen who developed were analyzed retrospectively. divided into three temporal stages, early, medium, late. Hepatic functions characteristics bile duct observed by...
Lymphomatoid granulomatosis (LYG) is a rare Epstein-Barr virus-associated lymphoproliferative disorder. The disease lacks specific clinical and radiological manifestations, which may delay definitive diagnosis. We report the case of 39-year-old man with pulmonary LYG who presented to hospital after experiencing three months fever, weight loss, dry cough exertional dyspnea. He was initially misdiagnosed pneumonia, polyangiitis infectious mononucleosis due non-specific manifestations disease....
Abstract Background Antiretroviral therapy (ART) demonstrates high efficacy in reducing the risk of HIV transmission to sexual partners. However, it is not clear if use pre-exposure prophylaxis (PrEP) HIV-1-serodiscordant couples necessary during natural conception when HIV-positive partner exhibits a suppressed viral load. The purpose this study was assess role PrEP population. Methods A retrospective, multicenter conducted cohort (positive man, negative woman) with childbearing desires....