A5115044953- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Tuberculosis Research and Epidemiology
- Cancer-related molecular mechanisms research
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Bone health and osteoporosis research
- Bone Metabolism and Diseases
- Blood Pressure and Hypertension Studies
- Abdominal Trauma and Injuries
- HIV/AIDS Research and Interventions
- Organ Transplantation Techniques and Outcomes
- Multiple and Secondary Primary Cancers
- Diagnosis and treatment of tuberculosis
- Sex work and related issues
- Neurological Disease Mechanisms and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Growth Hormone and Insulin-like Growth Factors
- Cardiovascular Health and Disease Prevention
- Long-Term Effects of COVID-19
- Adipokines, Inflammation, and Metabolic Diseases
- HIV, Drug Use, Sexual Risk
First Affiliated Hospital of Gannan Medical University
2025
Changzhi Medical College
2010-2025
Peking University
2014-2025
Army Medical University
2013-2024
Southwest Hospital
2013-2024
Zhongshan People's Hospital
2011-2024
Southern Medical University
2024
Nanfang Hospital
2012-2024
Fujian Medical University
2013-2024
Hezhou University
2024
Rabies is a zoonotic disease that remains an important public health problem worldwide and causes more than 70,000 human deaths each year. The causative agent of rabies virus (RV), negative-stranded RNA the rhabdovirus family. Neuroinvasiveness neurotropism are main features define pathogenesis rabies. Although RV pathogenicity multigenic trait involving several elements genome, glycoprotein plays major role in by controlling rate uptake trans-synaptic spread, regulating replication....
This Surgical Innovation describes the use of anatomic resection liver based on portal territory with margin priority for treatment hepatocellular carcinoma.
ABSTRACT Postexposure treatment (PET) of wild-type rabies virus (RV)-infected mice with a live-attenuated triple-glycoprotein RV variant (TriGAS) promotes survival but does not prevent the pathogenic from invading and replicating in brain. Successful PET is associated induction robust virus-neutralizing antibody response clearance brain tissues. Comparison transcriptomes normal mouse those wild-type-RV-infected that had received either mock or TriGAS revealed many host genes activated...
The problem of population aging is a critical public health concern in modern China, and more tuberculosis (TB) control efforts are needed to reach elderly people at high priority. In this study, we aim determine the prevalence identify risk factors TB among China. A multistage cluster-sampled cross-sectional survey was conducted 2013, 27 clusters were selected from 10 counties provinces All consenting participants greater than or equal 65 years age screened for pulmonary with chest X-ray...
We recently reported that epicatechin, a bioactive compound occurs naturally in various common foods, promoted general health and survival of obese diabetic mice. It remains to be determined whether epicatechin extends span delays the process aging. In present study, or its analogue epigallocatechin gallate (EGCG) (0.25% w/v drinking water) was administered 20-mo-old male C57BL mice fed standard chow. The goal determine antiaging effect. results showed supplementation with for 37 wk...
Abstract Background In December 2019, human infection with a novel coronavirus, known as SARS-CoV-2, was identified in Wuhan, China. The mortality of critical illness high Wuhan. Information about critically ill patients SARS-CoV-2 outside Wuhan is scarce. We aimed to provide the clinical features, treatment, and prognosis Guangdong Province. Methods this multi-centered, retrospective, observational study, we enrolled pneumonia who were admitted intensive care unit (ICU) Demographic data,...
Two hundred twenty-four breast cancer patients with paired tissue and plasma samples were enrolled from 3 clinical centers to evaluate sensitivity specificity of a digital PCR HER2 amplification assay. All histologically confirmed diagnosis locally advanced recurrent or metastatic stage III/IV had status determinations using IHC/FISH. For the whole 224 patients, between dPCR in IHC/FISH is 43.75% (42/96), 84.38% (108/128) overall concordance 66.96% (150/224). Interestingly, when we looked at...
Ventriculostomy drainage is one of the commonly used surgical techniques in neurocritical care, which can relieve intracranial hypertension and facilitate postoperative cerebrospinal fluid pressure monitoring. By placing a tube ventricle, blood accumulation within ventricle are drained out brain, reducing preventing brain tissue damage. Clinically, speed ventriculostomy often controlled by measuring height difference between opening plane ensuring safe effective reduction pressure,...
Chronic metabolic acidosis increases urinary calcium excretion without altering intestinal absorption, suggesting that bone mineral is the source of additional calcium. In vivo and in vitro studies have shown causes a loss while buffering hydrogen ions. Previously, we studied changes femoral, midcortical ion concentrations after 7 days induced by oral ammonium chloride. We found that, compared with mice drinking only distilled water, chloride sodium potassium depletion HCO 3 − phosphate....
Acute kidney injury (AKI) is one of the most common organ dysfunction in sepsis, and increases risk unfavourable outcomes. Renal replacement therapy (RRT) predominant treatment for sepsis-associated AKI (SAKI). However, to date, no prospective randomised study has adequately addressed whether initiating RRT earlier will attenuate renal improve outcome sepsis. The objective trial compare early strategy with delayed on outcomes patients SAKI intensive care unit (ICU).This a large-scale,...
Objective This study assessed the association between erectile dysfunction (ED) and arthritis. Methods Weighted logistic regression subgroup analyses were used to investigate arthritis incidence ED among participants in 2001–2004 National Health Nutrition Examination Survey database. Results Among participants, 27.8% 18.5% had a self-reported history of arthritis, respectively. was associated with (odds ratio [OR]=4.00; 95% confidence interval [CI]: 3.20–4.99; p<0.001], which remained...
Metformin (MET) is taken as a principal medication for remedying Type 2 diabetes mellitus. Its anti-tumor effect has been reported increasingly, but the precise mechanism of it remains unclear. This study aims to explore efficacy MET and combined with nitric oxide donor prodrug JS-K on proliferation, apoptosis, DNA damage in human renal cell carcinoma (RCC) cells, investigate possible molecular involved. The proliferation was tested through methyl-tetrazolium assay apoptosis ascertained by...