A5092521279- HIV Research and Treatment
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Pediatric health and respiratory diseases
- Cytomegalovirus and herpesvirus research
- Bacteriophages and microbial interactions
- Plant and Fungal Interactions Research
- Animal Virus Infections Studies
- Viral-associated cancers and disorders
- Galectins and Cancer Biology
- Hepatitis C virus research
- Gut microbiota and health
- Infant Nutrition and Health
- Clostridium difficile and Clostridium perfringens research
- Plant Virus Research Studies
- Immune Cell Function and Interaction
Jawaharlal Nehru University
2023-2024
The microbiome is an integral part of the human gut, and it plays a crucial role in development immune system homeostasis. Apart from gut microbiome, airway microbial community also forms distinct microbiota. Furthermore, several studies indicate existence communication between their metabolites with lung airways, called "gut–lung axis". Perturbations microbiota composition, termed dysbiosis, can have acute chronic effects on pathophysiology diseases. Microbes stimulate various innate...
Background:: The plasma virome represents the overall composition of viral sequences present in it. Alteration has been reported treatment naïve and immunocompromised (CD4 count < 200) people with HIV (PWH). However, effect ART on PWH preserved CD4 counts is poorly understood. Objective:: We aimed to assess alterations comparison HIV-negative uninfected controls further investigate possible associations viruses inflammation immune dysfunction, namely, immunosenescence exhaustion....
Abstract Background: High levels of Galectin-9 (Gal-9), a β-galactoside-binding mammalian lectin, are associated with systemic inflammation in chronic viral infections like HIV, despite suppression by ART. Gut-systemic microbial translocation is major contributor persistent inflammation. Whether Gal-9 influences the integrity gut during remains unknown. Objective: Here we investigated impact interplay between gut-systemic setting well-treated HIV infection. Method: We assessed and sCD14...
Abstract Microbiome study during HIV infection is widely documented with major emphasis on bacteriome, while virome studies are few. The alteration of plasma reported in patients who either treatment naïve or have a weak immune system. Less known about the HIV-infected ART preserved CD4 counts. In our pilot study, viral DNA isolated from was sequenced Illumina Nextseq500 platform. With help VIROMATCH pipeline, we observed that were significantly distinct controls basis Bray-Curtis...