- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Plant-Microbe Interactions and Immunity
- Microbial Metabolic Engineering and Bioproduction
- Plant nutrient uptake and metabolism
- Genomics and Phylogenetic Studies
- Plant Gene Expression Analysis
- Cytokine Signaling Pathways and Interactions
- Trypanosoma species research and implications
- Trace Elements in Health
- Advanced Glycation End Products research
- Nanotechnology research and applications
- RNA modifications and cancer
- GABA and Rice Research
- COVID-19 and healthcare impacts
- Biofuel production and bioconversion
- Nanoparticle-Based Drug Delivery
- Research on Leishmaniasis Studies
- Biochemical and biochemical processes
- Curcumin's Biomedical Applications
- Heavy Metals in Plants
- Vanadium and Halogenation Chemistry
Jawaharlal Nehru University
2011-2025
Rai University
2024
Himalayan University
2024
Central University of Punjab
2020
International Centre for Genetic Engineering and Biotechnology
2006-2016
Indian Institute of Technology Delhi
2009
Abstract Background Metallothioneins (MT) are low molecular weight, cysteine rich metal binding proteins, found across genera and species, but their function(s) in abiotic stress tolerance not well documented. Results We have characterized a rice MT gene, OsMT1e-P , isolated from subtractive library generated stressed salinity tolerant genotype, Pokkali. Bioinformatics analysis of the genome sequence revealed that this gene belongs to multigenic family, which consists 13 genes with 15...
Glyoxalase pathway, comprising glyoxalase I (GLY I) and II II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH). However, in bacteria, III III) with DJ-1/PfpI domain(s) can do same conversion a single step without GSH. Our investigations presence domain containing proteins plants have indicated existence GLY III-like monocots, dicots, lycopods, gymnosperm bryophytes. A deeper silico analysis rice genome identified...
The two-component system (TCS), which works on the principle of histidine-aspartate phosphorelay signaling, is known to play an important role in diverse physiological processes lower organisms and has recently emerged as signaling plants. Employing tools bioinformatics, we have characterized TCS candidate genes genome Oryza sativa L. subsp. japonica. We present a complete overview gene families O. sativa, including structures, conserved motifs, chromosome locations, phylogeny. Our analysis...
Abstract Background In Arabidopsis thaliana (L.) Heynh and Oryza sativa L., a large number of genes encode proteins unknown functions, whose characterization still remains one the major challenges. With an aim to characterize these having defined features (PDFs) in plants, we have chosen work on cystathionine β-synthase (CBS) domain. CBS domain as such has no function(s) but plays regulatory role for many enzymes thus helps maintaining intracellular redox balance. Its function sensor...
Methylglyoxal (MG) is a toxic metabolite produced primarily as byproduct of glycolysis. Being potent glycating agent, it can readily bind macromolecules like DNA, RNA, or proteins, modulating their expression and activity. In plants, despite the known inhibitory effects MG on growth development, still limited information available about molecular mechanisms response pathways elicited upon elevation in levels. To gain insight into basis response, we have investigated changes global gene...
The extent to which the presence of a biomolecular solute modifies local energetics water molecules, as measured by tagged molecule potential energy (TPE), is examined using molecular dynamics simulations β-hairpin 2GB1 and α-helix deca-alanine in water. CHARMM22 force field, conjunction with TIP3P solvent model, used for peptides, SPC/E benchmarks behavior bulk solvent. shown have significantly lower tetrahedral order higher binding than at same state point. models show very similar...
Two-component system (TCS) is one of the key signal sensing machinery which enables species to sense environmental stimuli. It essentially comprises three major components, sensory histidine kinase proteins (HKs), phosphotransfer (Hpts), and response regulator (RRs). The members TCS family have already been identified in Arabidopsis rice but knowledge about their functional indulgence during various abiotic stress conditions remains meager. Current study an attempt carry out comprehensive...
Response to stress represents a highly complex mechanism in plants involving plethora of genes and gene families. It has been established that use some common set families for both biotic abiotic responses leading cross-talk phenomena. One such family, Meprin And TRAF Homology (MATH) domain containing protein (MDCP), known be involved response. In this study, we present genome-wide identification various members MDCP family from Arabidopsis rice. A large number identified rice indicate...
Cobalt oxide/graphene oxide (Co3O4/GO) nanocomposites were synthesised using the co-precipitation synthesis process. The polycrystalline nature of Co3O4 nanoparticles onto GO sheets is studied by X-ray diffraction (XRD) pattern where found in with a particle size 35 nm. structural and morphological field emission scanning electron microscopy (FESEM) EDX, distribution on nanosheets was observed. effect Raman spectrometer enhancement peaks after decoration nanosheets. It observed that ID/IG...
Abstract We conducted a molecular study of parasite sequences from cohort cutaneous leishmaniasis patients in Himachal Pradesh, India. Results revealed atypical disease caused by Leishmania donovani parasites. L. variants causing manifestations this region are different those visceral northeastern