- CCD and CMOS Imaging Sensors
- Gastrointestinal Bleeding Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Image Processing Techniques and Applications
- Infrared Target Detection Methodologies
- Neuroscience and Neural Engineering
- Cardiac Structural Anomalies and Repair
- Surgical Simulation and Training
- Cardiac pacing and defibrillation studies
- Minimally Invasive Surgical Techniques
- Augmented Reality Applications
- Fuel Cells and Related Materials
- Gastrointestinal disorders and treatments
- Analytical Chemistry and Sensors
- Salivary Gland Disorders and Functions
- Gastric Cancer Management and Outcomes
- Advanced Optical Imaging Technologies
- Cardiac Arrest and Resuscitation
- Gastrointestinal Tumor Research and Treatment
- Advanced Biosensing Techniques and Applications
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Soft Robotics and Applications
- Analog and Mixed-Signal Circuit Design
- Oral microbiology and periodontitis research
University of Pisa
2016
Institut des Sciences Analytiques
2016
Université Claude Bernard Lyon 1
2016
Scuola Superiore Sant'Anna
2009-2016
Piaggio (Italy)
2010-2015
In this paper, the authors present an innovative vision platform for laparoendoscopic single-site (LESS) surgery based on a wired and magnetically activated 5-degrees-of-freedom robot with stereovision. The stereoscopic module, developed using two off-the-shelf cameras light emitting diodes lighting system, is mounted tip. An autostereoscopic screen adopted to display surgical scenario as alternative 3-D helmets or polarizing glasses. A rough position of stereocamera can be determined along...
A CMOS pixel with linear-logarithmic response and programmable dynamic range (DR), based on a tunable transition point, has purposely been designed for endoscopic applications. theoretical model of the was developed validated. chip 100×100 array 12-b digital output fabricated in 0.35-μm technology fully tested, thus demonstrating state-of-the-art performance terms DR noise. Intraframe proved to be extendable more than 110 dB through logarithmic compression signal light irradiation power...
A high dynamic range CMOS image sensor providing a user-programmable power responsivity curve is presented. Each pixel integrates, besides 4T active structure, voltage comparator and an analog memory to implement time-to-saturation scheme while also the standard integrated photo-current signal. The generates two 10-bit outputs allowing typical exceeding 120 dB with temporal noise lower than 0.13% fixed pattern of 0.4% (1.7%) total signal swing (2 V) at low (high) irradiance without any...
Prediction of disease progression using saliva as a diagnostic medium has roused the interest scientific researchers in 10 last past years. Potentially important biomarkers are increased during local and systemic inflammation. In present study we have developed highly sensitive biosensor for TNF-α detection human patients suffering from heart failure. Therefore, fully integrated electrochemical BioMEMS was order to increase sensitivity detection, decrease time analysis, simultaneously detect...
This paper aims to contribute the advancement of Wireless Capsule Endoscopy (WCE) field for ColoRectal Cancer (CRC) screening, by developing all electronic circuits build an innovative wireless endoscopic capsule with a spherical shape, conceived reduce friction during its locomotion and thus improving patient's acceptability. The proposed embeds image sensor optics Light Emitting Diodes (LEDs), control unit telemetry module, actuation system, battery smart recharging circuit able recharge...
In the near future, it is likely that 3-dimensional (3D) surgical endoscopes will replace current 2D imaging systems given rapid spreading of stereoscopy in consumer market. this evaluation study, an emerging technology, autostereoscopic monitor, compared with visualization mainly used laparoscopic surgery: a binocular visor, technically equivalent from viewer’s point view to da Vinci 3D console, and standard monitor. A total 16 physicians no experience interfaces performed 5 different...
Nowadays advanced heart failure is mainly treated through transplantation. However, the low availability of donors makes research alternative therapies urgent. Continuous-flow left ventricular assist devices (LVADs) are going to assume a more significant role in assisting failing heart. A recent challenge clinical practice possibility use LVAD as long-term therapy rather than bridge For this reason, comfortable devices, able dynamically adapt physiological cardiac demand relation patient...
A CMOS image sensor with programmable dynamic range linear-logarithmic response through tunable transition point and fixed pattern noise correction is presented. Each 9.4x9.4 mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> pixel cell integrates a 5T active structure hard reset an load for the high light logarithmic behavior. chip 100x100 array 12-bit digital output has been fabricated in 0.35um, 3.3V standard technology. The of can...
A high dynamic range CMOS image sensor providing a user-programmable power responsivity curve is presented. Each 15 times 15mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> -pixel cell integrates, besides 4T active pixel structure, voltage comparator and an analog memory to implement time-to-saturation scheme while also the standard integrated photo-current signal. 140 l40-pixel array has been fabricated in 0.35-mum, 3.3-V technology....
In this paper, an Autoregulation Unit (ARU) for left ventricular sensorized assist devices (LVAD) has been used with a cardiovascular hybrid simulator mimicking physiological and pathological patient conditions. The functionalities of the ARU have demonstrating successful receiving visualization system parameters, sending commands LVAD speed changes, enabling autonomous flow control algorithm. Experiments changes autoregulation are reported, showing feasibility approach both local remote LVAD.
In this work we present an innovative algorithm for the dynamic control of ventricular assist devices (VADs), based on acquisition continuous physiological and functional parameters such as heart rate, blood oxygenation, temperature, patient movements. Such are acquired by wearable (MagIC & Winpack) sensors implanted close to VAD. The aim proposed is dynamically hydraulic power VAD a function detected parameters, patient's activity emotional status. way, cardiac dynamics regulated...
A custom CMOS image sensor for capsular endoscopy is presented. The complete functionality of the chip guaranteed through seven signal pins, used I2C like input and LVDS output interfaces. Prototypes have been produced in UMC 0.18μm-CIS (CMOS Image Sensor) technology both monochrome colour-RGB versions. imager has electrically optically characterized ex-vivo images acquired evaluated. results characterization show state art performance terms power consumption (<40mW) light sensitivity (0.1...
This paper describes an integrated system for facing heart failures (HF) in innovative way. Existing left ventricular assist devices (LVAD or VAD) are usually devoted to blood pumping without the possibility adapt speed patient conditions during everyday activities. is essentially due lack of sensorization, bulkiness, and need relying on device-specific controllers with reduced computing ability existing systems. In this work, portable device, ARU, presented enhancing VADs applicability as a...
Ventricular Assist Devices (VADs) have been lately considered as an efficient destination therapy for heart disease, achieving remarkable survival scores. This paper presents integrated end-to-end VAD patient architecture consisting of a web-based HL7 compatible Specialist Monitoring Application,
The biomedical environment is one of the most recent and interesting application fields for CMOS image sensors. Low power consumption, high sensitivity a simple interface are main required features; nevertheless dynamic range can be considered more less investigated aspects. High Dynamic research NeuriCam has been involved in since its incipit. This work an excursus NeuriCam's approaches to this topic.
The aim of this work is the development a custom vision system for capsule endoscopy enabling real time data stream at 20 fps. core components imager purposely developed target application, combined with red, green and blue LEDs illumination low power FPGA sensor control, image compression interfacing transmission. also responsible control LEDs, which are synchronized acquisition in order to implement automatic lightning tuning global shutter condition. novelty approach that camera setting...