- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Conducting polymers and applications
- Electrochemical Analysis and Applications
- Molecular Junctions and Nanostructures
- Neuroscience and Neural Engineering
- Advanced Sensor and Energy Harvesting Materials
- Microfluidic and Capillary Electrophoresis Applications
- Insect and Pesticide Research
- Nanofabrication and Lithography Techniques
- Gas Sensing Nanomaterials and Sensors
- Biosensors and Analytical Detection
- Extracellular vesicles in disease
- Advanced Chemical Sensor Technologies
- Prosthetics and Rehabilitation Robotics
- Salivary Gland Disorders and Functions
- Semiconductor materials and devices
- Advanced Biosensing Techniques and Applications
- Mechanical Circulatory Support Devices
- Innovative Microfluidic and Catalytic Techniques Innovation
- Force Microscopy Techniques and Applications
- Olfactory and Sensory Function Studies
- 3D Printing in Biomedical Research
- Pharmacological Effects and Assays
Chouaib Doukkali University
2024-2025
Institut des Sciences Analytiques
2014-2023
Université Claude Bernard Lyon 1
2014-2023
Nanobiotix (France)
2014-2023
Centre National de la Recherche Scientifique
2014-2019
École Normale Supérieure de Lyon
2017-2018
Institut Néel
2014
École Supérieure d'Électronique de l'Ouest
2014
Université Nantes Angers Le Mans
2014
Thales (France)
2014
NT-proBNP is the gold standard biomarker for early diagnostics of heart failure, disease prevention, and stratified individualized patient care. In this work, we aim to develop a novel ultra-sensitive immunosensor direct detection in human artificial saliva (AS), which represents an intriguing biological matrix potentially rich biomarkers. The will enhance sensitivity detection, reduce measurement time, enable simultaneous various developed biosensor, based on working microelectrodes (WEs),...
Tumor necrosis factor-α (TNF-α) is a biomarker of inflammation that occurs in patients suffering from heart failure (HF). Saliva can be sampled non-invasive way, and it currently gaining importance as matrix alternative to blood diagnostic therapy monitoring. This work presents the development an immunosensor array based on eight screen-printed gold electrodes detect TNF-α saliva samples. Two different functionalization strategies were compared. In first, anti-TNF-α antibodies chemically...
Abstract In this work, we report the development of a highly sensitive capacitance chemical sensor based on copper C,C,C,C‐ tetra‐carboxylic phthalocyanine‐acrylate polymer adduct (Cu(II)TCPc‐PAA) for phosphate ions detection. A silicon nitride substrate Al−Cu/Si‐p/SiO 2 /Si 3 N 4 structure was used as transducer. These materials have provided good stability electrochemical measurements. The functionalized silicon‐based transducers with Cu(II)Pc‐PAA membrane were characterized by using...
Over the past years, to achieve better sensing performance, hafnium dioxide (HfO2) has been studied as an ion-sensitive layer. In this work, thin layers of were used pH-sensitive membranes and deposited by atomic layer deposition (ALD) process onto electrolytic-insulating-semiconductor structure Al/Si/SiO2/HfO2 for realization a pH sensor. The thicknesses HfO2 in work was 15, 19.5 39.9 nm. thickness controlled ALD during fabrication process. sensitivity toward H+ clearly higher when compared...
Abstract A K + ‐sensitive capacitive electrolyte‐membrane‐insulator‐semiconductor (EMIS) based on a novel dibromoaza[7]helicene ionophore has been developed. An ion‐sensitive membrane polyvinylchloride (PVC) doped with the was deposited Si 3 N 4 /SiO 2 /Si‐p/Cu‐Al transducer. The properties of ‐EMIS chemical sensor were investigated by electrochemical impedance spectroscopy (EIS). All developed devices upon being tested have shown good sensitivity and linearity responses within range 10 −6 M...
Prediction of disease progression using saliva as a diagnostic medium has roused the interest scientific researchers in 10 last past years. Potentially important biomarkers are increased during local and systemic inflammation. In present study we have developed highly sensitive biosensor for TNF-α detection human patients suffering from heart failure. Therefore, fully integrated electrochemical BioMEMS was order to increase sensitivity detection, decrease time analysis, simultaneously detect...