A5021546337- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Advanced Nanomaterials in Catalysis
- Drug Transport and Resistance Mechanisms
- Electrochemical sensors and biosensors
- Pharmacological Effects and Toxicity Studies
- Advanced Biosensing Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Aerosol Filtration and Electrostatic Precipitation
- Thyroid and Parathyroid Surgery
- Bacteriophages and microbial interactions
- Nanocluster Synthesis and Applications
- Polymer Surface Interaction Studies
- Pharmacogenetics and Drug Metabolism
- X-ray Diffraction in Crystallography
- Photoreceptor and optogenetics research
- nanoparticles nucleation surface interactions
- Signaling Pathways in Disease
- Particle Dynamics in Fluid Flows
- Radioactive element chemistry and processing
- Nanoplatforms for cancer theranostics
- Coagulation and Flocculation Studies
- Sleep and Wakefulness Research
- Sleep and related disorders
Xiangya Hospital Central South University
2021-2025
Central South University
2021-2025
Southwest University
2015-2024
University of Minnesota
2012-2024
The University of Texas at Dallas
2017-2024
Columbia University
2024
Sun Yat-sen University
2019-2023
The Seventh Affiliated Hospital of Sun Yat-sen University
2019-2023
Guangdong Academy of Sciences
2023
Fujian Medical University
2022-2023
A transparent, lateral-flow test strip coupled with a smartphone-based ambient light sensor was first proposed for detecting enzymatic inhibition and phosphorylation. The principle of the platform is based on simultaneous measurement total amount enzyme activity to biomonitor exposure organophosphorus (OP) pesticides. In this study, butyrylcholinesterase (BChE) adopted as model ethyl paraoxon chosen an analyte representing OP BChE quantified by sensitive colorimetric signal originating from...
Manganese dioxide nanoflowers (MnO2 NFs) were synthesized and used as a dual readout probe to develop novel immunochromatographic test strip (ITS) for detecting pesticide residues using chlorpyrifos the model analyte. MnO2 NFs-labeled antibody was employed signal tracer conducting ITS. After 10 min competitive immunoreaction, captured by immobilized immunogen in strip, resulting NFs on line. The led appearance of brown color line, which could be easily observed naked eye qualitative readout....
Superior to traditional nanoscale catalysts, single-atom site catalysts (SASCs) show such merits as maximal catalysis efficiency and outstanding catalytic activity for the construction of analytical methodological platforms. Hereby, an in situ etching strategy was designed prepare yolk-shell Co SASCs derived from ZIF-8@SiO2 nanoparticles. On basis direct chemical interactions between precursors supports, element with isolated atomic dispersion anchored on The possess high Fenton-like thus...
Single-atom nanozymes (SANs) with highly exposed active sites and remarkable catalytic activity have shown noteworthy practicability in heterogeneous catalysis-based bioassay. Nevertheless, most of them were reported peroxidase-like ordinary loading capability. It is still a challenge to prepare high-loading SANs desirable superoxide dismutase (SOD)-like activity. In this work, Mn SAN was successfully confined the frameworks Prussian blue analogues formed on Ti3C2 MXene sheets assistance...
Approximately 25% of Americans suffer from laryngopharyngeal reflux (LPR), a disease for which no effective medical therapy exists. Pepsin is predominant source damage during LPR and key therapeutic target. Fosamprenavir (FOS) inhibits pepsin prevents in an mouse model. Inhaled FOS protects at lower dose than oral; however, the safety inhaled unknown there are inhalers delivery. A pre-Good Lab Practice (GLP) study was performed to assess computational fluid dynamics (CFD) modeling used...
To date, most collision cross section (CCS) predictions have invoked gas molecule impingement-reemission rules in which specular and elastic scattering of spherical molecules from rigid polyatomic surfaces are assumed. Although such been shown to agree well with CCSs measured helium bath gas, a number studies reveal that these do not for ions diatomic gases, namely, air molecular nitrogen. further examine the validity specular-elastic versus diffuse-inelastic models, we positively charged...
Collisional growth and ionization is commonplace for gas phase nanoparticles (i.e., in aerosols). Nanoparticle collisions atmospheric pressure environments occur the mass transfer transition regime, further attractive singular contact potentials (which arise when modeling as condensed matter which potential energy approaches -∞ two entities contact) often have a non-negligible influence on collision processes. For these reasons rate calculations are not straightforward. We use mean first...
The sorption of vapor molecules onto pre-existing nanometer sized clusters is importance in understanding particle formation and growth gas phase environments devising separation schemes. Here, we apply a differential mobility analyzer-mass spectrometer based approach to observe directly the iodide cluster ions form (MI)xM(+) (x = 1-13, M Na, K, Rb, or Cs) air at 300 K with water saturation ratios 0.01-0.64 range. extent quantified measurements by shift collision cross section (CCS) for each...
Abstract Co single‐atom catalysts (SACs) with good aqueous solubility and abundant labelling functional groups were prepared in Co/Fe bimetallic metal‐organic frameworks by a facile solvothermal method without high‐temperature calcination. In contrast to traditional chemiluminescence (CL) catalysts, SACs accelerated decomposition of H 2 O produce large amount singlet oxygen ( 1 ) rather than superoxide (O .− hydroxyl radical (OH . ). They found dramatically enhance the CL emission luminol‐H...
Neuropeptides are abundant signaling molecules in the central nervous system. Yet remarkably little is known about their spatiotemporal spread and biological activity. Here, we developed an integrated optical approach using Plasmonic nAnovesicles cell-based neurotransmitter fluorescent engineered reporter (CNiFER), or PACE, to probe neuropeptide mouse neocortex. Small volumes (fL pL) of exogenously supplied somatostatin-14 (SST) can be rapidly released under near-infrared light stimulation...
A virulent bacteriophage highly specific to Pseudomonas aeruginosa (P. aeruginosa) was isolated from hospital sewage using a lambda isolation protocol. The bacteriophage, named as PAP1, used functionalize tosyl-activated magnetic beads establish bacteriophage-affinity strategy for separation and detection of viable P. aeruginosa. Recognition the target bacteria by tail fibers baseplate led capture onto beads. After replication cycle about 100 min, progenies lysed released intracellular...
Recent studies of new particle formation events in the atmosphere suggest that nanoclusters (i.e, species formed during early stages growth which are composed 10(1)-10(3) molecules) may consist amines and sulfuric acid. The physicochemical properties sub-10 nm amine-sulfuric acid clusters hence interest. In this work, we measure density, thermostability, extent water uptake <8.5 effective diameter dimethylamine-sulfuric (DMAS) gas phase, produced via positive electrospray ionization....
Vascular dementia (VD) is a syndrome characterized by progressive cognitive decline. According to previous studies, stroke considered be risk factor for VD. The disruption of the blood-brain barrier (BBB) pivotal pathology stroke, as it contributes post-stroke inflammation and edema. It has been reported that Eph/Ephrin signaling pathway serves an important role in central nervous system injury. However, EphrinA1/EphA4 BBB damage following ischemic not yet reported. Oxygen-glucose...