A5079224479- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Advanced Polymer Synthesis and Characterization
- Advanced Nanomaterials in Catalysis
- Advanced Biosensing Techniques and Applications
- Electrochemical sensors and biosensors
- Bacteriophages and microbial interactions
- Photopolymerization techniques and applications
- biodegradable polymer synthesis and properties
- Synthetic Organic Chemistry Methods
- Pharmacological Effects and Assays
- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Antibiotics Pharmacokinetics and Efficacy
- Analytical Chemistry and Sensors
- Dendrimers and Hyperbranched Polymers
- Bacterial Identification and Susceptibility Testing
- Metal-Organic Frameworks: Synthesis and Applications
- Nanocluster Synthesis and Applications
- Synthesis and properties of polymers
- Molecular Sensors and Ion Detection
- Radioactive element chemistry and processing
- Analytical chemistry methods development
- Electrospun Nanofibers in Biomedical Applications
- Covalent Organic Framework Applications
Southwest University
2016-2025
State Key Laboratory of Silkworm Genomic Biology
2022-2024
Beijing University of Chemical Technology
2011-2023
Second Affiliated Hospital of Harbin Medical University
2022
Harbin Medical University
2022
Yichun University
2021
University of Hong Kong
2018
Pharmaceutical Biotechnology (Czechia)
2014-2018
Chongqing University
2014-2018
Jiujiang University
2017
Manganese dioxide nanoflowers (MnO2 NFs) were synthesized and used as a dual readout probe to develop novel immunochromatographic test strip (ITS) for detecting pesticide residues using chlorpyrifos the model analyte. MnO2 NFs-labeled antibody was employed signal tracer conducting ITS. After 10 min competitive immunoreaction, captured by immobilized immunogen in strip, resulting NFs on line. The led appearance of brown color line, which could be easily observed naked eye qualitative readout....
Superior to traditional nanoscale catalysts, single-atom site catalysts (SASCs) show such merits as maximal catalysis efficiency and outstanding catalytic activity for the construction of analytical methodological platforms. Hereby, an in situ etching strategy was designed prepare yolk-shell Co SASCs derived from ZIF-8@SiO2 nanoparticles. On basis direct chemical interactions between precursors supports, element with isolated atomic dispersion anchored on The possess high Fenton-like thus...
Single-atom nanozymes (SANs) with highly exposed active sites and remarkable catalytic activity have shown noteworthy practicability in heterogeneous catalysis-based bioassay. Nevertheless, most of them were reported peroxidase-like ordinary loading capability. It is still a challenge to prepare high-loading SANs desirable superoxide dismutase (SOD)-like activity. In this work, Mn SAN was successfully confined the frameworks Prussian blue analogues formed on Ti3C2 MXene sheets assistance...
Nanosized metal-organic frameworks (MOFs) NH2-MIL-53(Al) were synthesized from 2-aminoterephthalic acid (NH2·H2BDC) and AlCl3 by a facile hydrothermal method. The MOFs displayed good stability uniform particle size in netural medium hydrolyzed alkaline to release large amount of fluorescent ligand NH2·H2BDC. Therefore, they can act as large-capability nanovehicles load signal molecules for investigating various biorecognition events. In this work, based on the hydrolysis behavior...
As a potential antibacterial agent, endolysin can directly lyse Gram-positive bacteria from the outside and does not lead to drug resistance. Considering that XN108 is first reported methicillin-resistant Staphylococcus aureus (MRSA) strain in mainland China with vancomycin MIC exceeds 8 µg mL -1 , we conducted systematic study on its phage-encoded LysP108. Standard plate counting method revealed LysP108 could S. Pseudomonas aeruginosa damaged outer membrane, resulting significant reduction...
Design of a ratiometric method is promising pathway to improve the sensitivity and reliability electrochemiluminescent (ECL) assay, for which signals produced at two distinct potentials change reversely as it applied target analyte. Herein, biosensor ECL assay methicillin-resistant Staphylococcus aureus (MRSA) was constructed by immobilizing porcine IgG capturing MRSA onto an electrode that precoated with β-cyclodextrin-conjugated luminol nanoparticles (β-CD-Lu NPs) anodic luminophore. MOF...
A novel flow-through immunosensing system for performing a multianalyte chemiluminescent determination in single run was designed. new analytical strategy of substrate zone-resolved technique proposed. Using carcinoma antigen 125 (CA 125) and carcinoembryonic (CEA) as model analytes, the capture antibodies CA CEA were immobilized on an UltraBind aldehyde-actived membrane to act immunoreactor, which mixture 125, CEA, their corresponding tracers, horseradish peroxidase (HRP)-labeled anti-CA...
A two-dimensional resolution system of channels and substrate zones was proposed for multiplex immunoassay performed with a designed multichannel chemiluminescent (CL) detection device coupled single photomultiplier. Using carcinoma antigen 125 (CA 125), 153 153), 199 199), carcinoembryonic (CEA) as two couples model analytes, capture antibodies were immobilized in channels, respectively. With sandwich format, the CL substrates alkaline phosphatase horseradish peroxidase delivered into...
The multianalyte immunoassay (MIA) has attracted increasing attention due to its high sample throughput, short assay time, low consumption, and reduced overall cost. However, up now, the reported MIA methods commonly require multiple antibodies since each antibody can recognize only one antigen. Herein, a novel bispecific monoclonal (BsMcAb) that could bind methyl parathion imidacloprid simultaneously was produced by hybrid hybridomas strategy. A chemiluminescence (CL) reaction...